Forces Shaping China's Interprovincial Inequality

China, regional development, production

Oral History Interview with Tsui Kai Chong: Conceptualising SMU

This is an abridged version of the original interview. Please contact the Library at [email protected] for access to the full version of the transcript and/or audio recording.</p

The Plea for Asia—Tan Yunshan, Pan-Asianism and Sino-Indian Relations

In 1927, the Buddhist scholar, Tan Yunshan, travelled to Santiniketan on the invitation of Rabindranath Tagore to teach Chinese at Visva Bharati University. Subsequent years would see him develop close ties with the Guomindang and Congress leaders, secure Chinese state funding for the first sinological institute in India and mediate between the nationalist movements during the Second World War. That a relatively marginal academic, who participated in neither the May Fourth Movement nor any major political party, and who had little prior experience of India, could have played such an important role in twentieth century Sino-Indian relations raises questions over the conditions that made possible Tan‘s illustrious career. This article argues that Tan‘s success as an institution builder and diplomatic intermediary was attributable to his ideological affinity with the increasing disillusionment with capitalist modernity in both China and India, the shifting dynamics of the Pan-Asianist movement and the conservative turn of China‘s nationalist movement after its split with the communists in 1927. While Nationalist China and the Congress both tapped into the civilizational discourse that was supposed to bind the two societies together, the idealism Tan embodied was unable to withstand the conflict of priorities between nation-states in the emerging Cold War order

China's Forgotten Revolution: Radical Conservatism in Action, 1927-1949

This dissertation examines Republican China's state-led revolution under the Guomindang. Since the anti-Communist purge in 1927, the party-state had strived to re-energize mass activism and dissolve proletarian political subjectivity with a rightwing program that stressed interclass and national unity. Under Chiang Kai-shek's leadership, the Guomindang put an end to the ideological ambiguity of Sun Yat-sen's national revolution, broke ties the party forged with the Communist International in 1923, and launched an all-round assault on the fledging Chinese Communist Party. Refusing to challenge unequal power relationships domestically and abroad, Guomindang leaders promised to bring China and Asia back to their cultural essence and towards a superior ethical order. Despite its conservative socio-economic agenda, the party retained a radical organizational mode it derived from revolutionary socialism that prized Leninist vanguardism, reliance on mass involvement and cultural transformation. The Chinese nation-state under Guomindang rule experienced a conservative revolution and partook in a global fascist current that swept across Asia, Europe and Latin America during the second quarter of the twentieth century. The distinctiveness of China's conservative revolution is demonstrated in this dissertation through a multilayered study of its ideological formulations, mass mobilization programs, and ability to garner support from outside the Guomindang domestically and abroad. Senior party ideologues among radical conservatives, who produced tracts attacking the Guomindang's Communist allies in the mid-1920s, provided theoretical justifications for the April 1927 purge and heralded the party-state's drastic shift to the right. In the 1930s and 1940s, the Guomindang state deployed the scouting and wartime spiritual mobilization movements to re-channel mass activism towards strengthening the nation's organic unity and consolidating defense against Japanese invasion. Potentially subversive popular demands were diffused through a new focus on refining and rationalizing consumption habits, time management and other social mores. Instead of political participation, popular will found expression in public rituals, physical recreation and cultural entertainments. Conservative revolutionaries were adept in building elite support. The state's goal of disciplining everyday life converged with liberal intellectual fear over a social order collapsing under mob rule. While uncomfortable with some authoritarian behaviors on the Guomindang's part, prominent liberals such as Zhu Guangqian shared the state's priority of reining in an intransigent mass society. Internationally, China's repudiation of Soviet-supported anti-imperialist activities led the Guomindang to appeal to cultural affinities in the overtures it extended to the Indian independence movement. The regime's celebration of Eastern spiritual superiority proved attractive to Pan-Asianists like Rabindranath Tagore and informed exchanges between the Guomindang and Indian National Congress at the height of the Second World War. In highlighting the ascendency of radical conservatism in China and its transnational circulation across Asia, this dissertation sheds light on the distinct qualities, often downplayed in the historical literature, of the Guomindang's revolutionary enterprise vis-à-vis the radical left

Cultural Assimilation and Architecture: GuanXi and the Legacy of the Chinese Canadian Church

Known for priding itself as a multicultural nation, Canada's multicultural attitude does not come without a cost - as immigrants establish their roots and interact with the diverse ethnic groups within their communities, the process of cultural assimilation inevitably occurs. The process of assimilation can create not only social withdrawal and isolation, but also painful divisions between generations of a single family. This often results in psychological and emotional stress, leading to the questioning and finally the abandonment of one’s home culture and origin identity. While this process can be seen as universal, this thesis focuses on Hong Kong Canadians and the tradition of GuanXi. GuanXi is an intricate relational network that is cultivated informally through social exchanges which govern Chinese attitudes towards long-term social relationships. GuanXi is an important yet disappearing element within Hong Kong identity, and the ability to recognize these bonds and utilize this network is rapidly being lost through the process of cultural assimilation. Using the suburban Chinese church, which remains one of the few typologies that bring different generations and cultures together, this thesis proposes employing the principles of GuanXi as a way to focus design intentions. The goal of the thesis is to design a building that helps to foster and preserve the generational ties eroded by assimilation, leaving behind a cultural legacy for future generations

Optimal stimulation duration of tens in the management of osteoarthritic knee pain

Objective: This study examined the optimal stimulation duration of transcutaneous electrical nerve stimulation (TENS) for relieving osteoarthritic knee pain and the duration (as measured by half-life) of post-stimulation analgesia. Subjects: Thirty-eight patients received either: (i) 20 minutes (TENS20); (ii) 40 minutes (TENS40); (iii) 60 minutes (TENS60) of TENS; or (iv) 60 minutes of placebo TENS (TENSPL) 5 days a week for 2 weeks. Methods: A visual analogue scale recorded the magnitude and pain relief period for up to 10 hours after stimulation. Results: By Day10, a significantly greater cumulative reduction in the visual analogue scale scores was found in the TENS40 (83.40%) and TENS60 (68.37%) groups than in the TENS20 (54.59%) and TENSPL (6.14%) groups (p 3 0.000), such a group difference was maintained in the 2-week followup session (p 3 0.000). In terms of the duration of post-stimulation analgesia period, the duration for the TENS40 (256 minutes) and TENS60 (258 minutes) groups was more prolonged than in the other 2 groups (TENS20 = 168 minutes, TENSPL = 35 minutes) by Day10 (p 3 0.000). However, the TENS40 group produced the longest pain relief period by the follow-up session. Conclusion: 40 minutes is the optimal treatment duration of TENS, in terms of both the magnitude (VAS scores) of pain reduction and the duration of post-stimulation analgesia for knee osetoarthritis.<br /

AAA ATPases as therapeutic targets: Structure, functions, and small-molecule inhibitors

ATPases Associated with Diverse Cellular Activity (AAA ATPase) are essential enzymes found in all organisms. They are involved in various processes such as DNA replication, protein degradation, membrane fusion, microtubule serving, peroxisome biogenesis, signal transduction, and the regulation of gene expression. Due to the importance of AAA ATPases, several researchers identified and developed small-molecule inhibitors against these enzymes. We discuss six AAA ATPases that are potential drug targets and have well-developed inhibitors. We compare available structures that suggest significant differences of the ATP binding pockets among the AAA ATPases with or without ligand. The distances from ADP to the His20 in the His-Ser-His motif and the Arg finger (Arg353 or Arg378) in both RUVBL1/2 complex structures bound with or without ADP have significant differences, suggesting dramatically different interactions of the binding site with ADP. Taken together, the inhibitors of six well-studied AAA ATPases and their structural information suggest further development of specific AAA ATPase inhibitors due to difference in their structures. Future chemical biology coupled with proteomic approaches could be employed to develop variant specific, complex specific, and pathway specific inhibitors or activators for AAA ATPase proteins

Lack of a Y-Chromosomal Complement in the Majority of Gestational Trophoblastic Neoplasms

Gestational trophoblastic neoplasms (GTNs) are a rare group of neoplastic diseases composed of choriocarcinomas, placental site trophoblastic tumors (PSTTs) and epithelioid trophoblastic tumors (ETTs). Since these tumors are derivatives of fetal trophoblastic tissue, approximately 50% of GTN cases are expected to originate from a male conceptus and carry a Y-chromosomal complement according to a balanced sex ratio. To investigate this hypothesis, we carried out a comprehensive analysis by genotyping a relatively large sample size of 51 GTN cases using three independent sex chromosome genetic markers; Amelogenin, Protein Kinase and Zinc Finger have X and Y homologues that are distinguishable by their PCR product size. We found that all cases contained the X-chromosomal complement while only five (10%) of 51 tumors harbored the Y-chromosomal complement. Specifically, Y-chromosomal signals were detected in one (5%) of 19 choriocarcinomas, one (7%) of 15 PSTTs and three (18%) of 17 ETTs. The histopathological features of those with a Y-chromosome were similar to those without. Our results demonstrate the presence of a Y-chromosomal complement in GTNs, albeit a low 10% of cases. This shortfall of Y-chromosomal complements in GTNs may reinforce the notion that the majority of GTNs are derived from previous molar gestations