Izvješće sa simpozija o cijepljenju

Simpozij o cijepljenju održan je 14. ožujka 2015 u Hrvatskom liječničkom zboru

Influenza Vaccination

Cjepiva protiv gripe u upotrebi su desetljećima. U Hrvatskoj su u upotrebi podjedinična i fragmentirana cjepiva, koja se smatraju nešto manje djelotvornima od cjelostaničnih i živih atenuiranih cjepiva, ali su istodobno manje reaktogena. U svrhu poboljšanja imunogenosti i djelotvornosti cjepiva protiv gripe razvijena su adjuvantirana cjepiva i cjepivo za intradermalnu primjenu. Cijepljenje se tradicionalno preporučuje osobama pod povećanim rizikom od razvoja komplikacija gripe, osobama kojima bi gripa mogla ozbiljno pogoršati osnovnu bolest i zdravstvenim radnicima koji su u kontaktu s osjetljivim bolesnicima. Kao i sva druga cjepiva, tako ni cjepiva protiv gripe nisu savršena, tj. ne pružaju 100%-tnu zaštitu cijepljenim osobama i kod dijela cijepljenih osoba mogu izazvati nuspojave. Međutim očekivana korist od primjene cjepiva uvelike nadilazi potencijalni rizik, što jednako vrijedi za uobičajena sezonska cjepiva, kao i za pandemijsko, adjuvantirano cjepivo protiv gripe. Brojni dokazi o sigurnosti primjene i djelotvornosti cjepiva ne daju nimalo opravdanja za negativnu medijsku kampanju protiv ovog cjepiva, koje smo svjedoci od pojave pandemijskog cjepiva do danas.Influenza vaccines have b een u sed for decades. In Croatia only subunit and split vaccines are licensed. These vaccines are considered somewhat less efficient, but also less reactogenic than killed virion and live attenuated influenza vaccines. In order to increase immunogenicity and efficacy, adjuvanted vaccines and those for intradermal use have been developed. Influenza vaccination is traditionally recommended to people with increased risk factors for complications, those in whom influenza might aggravate underlying medical conditions and to healthcare workers caring for highrisk patients. As any other vaccine, influenza vaccines do not guarantee 100% protection and some people may develop adverse reactions. However, the expected benefits of vaccination clearly outweigh possible risks, which is true both for seasonal influenza vaccines and for pandemic adjuvanted vaccines. Numerous evidence of safety and efficacy of influenza vaccines provide absolutely no justification for the negative media campaign directed against influenza vaccines which began with the advent of pandemic vaccines

Impact of vaccination on vaccine-preventable disease burden in Croatia

The epidemiology of vaccine-preventable diseases is a result of numerous factors, among which organized active immunization is one of the most important. Analysis of trends in disease incidence of vaccine-preventable diseases is an adequate way to provide evidence of impact of vaccination on disease burden. In this manuscript, trends in vaccine-preventable diseases in Croatia are analyzed. Due to high vaccination coverage with safe and efficacious vaccines, some diseases like poliomyelitis and diphtheria have been eliminated in Croatia, while measles and rubella are at the point of elimination and burden of other vaccine-preventable diseases has been reduced significantly. Until recently, most of the vaccines used in the national immunization schedule have been produced by the Institute of Immunology, Zagreb, and the reduction of disease incidence is largely attributable to the Institute’s vaccines. This especially refers to the Koprowski oral polio vaccine, measles, mumps, rubella and diphtheria, tetanus, pertussis vaccines

Cijepljenje protiv bolesti uzrokovanih HPV tipovima 6, 11, 16 i 18

Agencija za lijekove i medicinske proizvode Republike Hrvatske je 19. rujna 2007.izdala odobrenje za puštanje u promet četverovalentnog HPV cjepiva.Gardasil (Merck & Co., inc.) je rekombinantno, adsorbirano cjepivo protiv humanog papilomavirusa tipova 6, 11, 16 i 18, namijenjeno sprečavanju teške displazije i raka vrata maternice i teške displazije stidnice uzrokovanih HPV-om tipa 16 i 18, te vanjskih genitalnih bradavica uzrokovanih HPV-om tipa 6 i 11

Talon Cusp: a Literature Review and Case Report

Kandžasta kvržica je akcesorna tvorba slična kvržici, a proteže se od vrata zuba ili cinguluma prema griznom bridu prednjeg zuba. Javlja se u objema denticijama – mliječnoj i trajnoj te kod obaju spolova. Ovaj rad donosi pregled literature te prikaz pacijenta s kandžastom kvržicom na oralnoj plohi maksilarnoga bočnog sjekutića. Navode se moguća etiologija, prevalencija, klasifi kacija, klinička i radiološka obilježja ove anomalije te načini liječenja.Talon cusp is an accessory cusp-like structure projecting from the tooth neck or cingulum area towards the incisal ridge of an anterior tooth. Both primary and permanent dentition are involved, and both sexes. This paper reviews the literature and presents a case of the talon cusp on the lingual surface of the maxillary lateral incisor in a male patient. Possible etiology, prevalence, classifi cation, clinical and radiographic characteristics of this anomaly and modes of treatment are described