The Role of Mentors/Advisors in the Doctoral Training of African American Students at Predominately White Universities: Implications for Doctoral Training

The purpose of this study is to examine the relationship and the importance of connecting the African American doctoral students and their advisors in the mentor roles. More specifically, this study brings to the forefront the importance as well as the impact of mentors/advisors and their roles in facilitating academic success for African American doctoral students. Many African American doctoral students are typically misunderstood and misdirected in the types of support that they may need to succeed in graduate school (Gallien & Peterson, 2005). Mentors/advisors and the roles that they have are essential to the success of African American doctoral students. The support structures surrounding the mentor/advisor relationship in this research are essential to how it relates to the needs of the African American doctoral student on a predominately White campus. Given the findings, recommendations are provided for future research and for administrators at predominately White Institutions

Approaches to Interpreting Mesolithic Mobility and Settlement in Britain and Ireland

The Mesolithic communities of northwest Europe have generally been considered inherently mobile, and all the material evidence associated with them has been interpreted accordingly. This has resulted in entrenched,theoretically polemical and largely hypothetical mobility models, focusing on seasonal rounds and extraction activities. However, recent reanalyses of the ethnographic sources, and discoveries of both substantial and ephemeral Mesolithic structures, as well as new data from recent innovative lithic and scientific analyses (including DNA, isotope research on human remains, and geochemical analyses of lithic artefacts), have forced us to rethink the rather static models of Mesolithic mobility strategies.This paper, examining Mesolithic hunter-gatherer mobility and settlement models from Britain and Ireland, is part of that reassessment. In particular, it assesses the impact of the multiple lines of consilience on our understanding of Mesolithic habitation of landscapes. These include the archaeological evidence and the efficacy of recent theoretical and methodological approaches that have been employed to interpret it

External-facing assessments: Balancing the needs of students, external partner organisations and the public

Students producing work directed at an external audience - whether a formal assessment, a ‘showcase portfolio’, or a selection of work curated by students outside the curriculum - is emerging as a critical field of enquiry and practice. Drawing on three case studies this roundtable examines the challenges and opportunities as they embed external-facing assessments in programmes of study. After a brief introduction to the institutional context of UCL’s initiatives relating to the Connected Curriculum Collab projects, we will present three different examples: co-produced public facing assessments (Thomas Kador), peer assessments after group work (Pilar Garcia Souto) and the use of portfolios (Nicole Brown). In the subsequent discussion we aim to explore the opportunities for building capacity to establish partnerships between students, external partner organisations and the public. We also discuss the role that educational professionals and colleagues might have in mediating between the institution, its students, staff, and other stakeholders

Orally Active Multi-Functional Antioxidants Delay Cataract Formation in Streptozotocin (Type 1) Diabetic and Gamma-Irradiated Rats

Age-related cataract is a worldwide health care problem whose progression has been linked to oxidative stress and the accumulation of redox-active metals. Since there is no specific animal model for human age-related cataract, multiple animal models must be used to evaluate potential therapies that may delay and/or prevent cataract formation.Proof of concept studies were conducted to evaluate 4-(5-hydroxypyrimidin-2-yl)-N,N-dimethyl-3,5-dioxopiperazine-1-sulfonamide (compound 4) and 4-(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)-N,N-dimethyl-3,5-dioxopiperazine-1-sulfonamide (compound 8), multi-functional antioxidants that can independently chelate redox metals and quench free radicals, on their ability to delay the progression of diabetic "sugar" cataracts and gamma radiation-induced cataracts. Prior to 15 Gy of whole head irradiation, select groups of Long Evans rats received either diet containing compound 4 or 8, or a single i.p. injection of panthethine, a radioprotective agent. Compared to untreated, irradiated rats, treatment with pantethine, 4 and 8 delayed initial lens changes by 4, 47, and 38 days, respectively, and the average formation of posterior subcapsular opacities by 23, 53 and 58 days, respectively. In the second study, select groups of diabetic Sprague Dawley rats were administered chow containing compounds 4, 8 or the aldose reductase inhibitor AL1576. As anticipated, treatment with AL1576 prevented cataract by inhibiting sorbitol formation in the lens. However, compared to untreated rats, compounds 4 and 8 delayed vacuole formation by 20 days and 12 days, respectively, and cortical cataract formation by 8 and 3 days, respectively, without reducing lenticular sorbitol. Using in vitro lens culture in 30 mM xylose to model diabetic "sugar" cataract formation, western blots confirmed that multi-functional antioxidants reduced endoplasmic reticulum stress.Multi-functional antioxidants delayed cataract formation in two diverse rat models. These studies provide a proof of concept that a general cataract treatment focused on reducing oxidative stress instead of a specific mechanism of cataractogenesis can be developed

Facilitating Transitions: Postmortem Processing of the Dead at the Carrowkeel Passage Tomb Complex, Ireland (3500–3000 cal. B.C.)

This study explores the burial practices and secondary funerary rites at the Carrowkeel Neolithic passage tomb complex in County Sligo in northwest Ireland. An osteological and taphonomic reassessment of cremated and unburned human bones recovered from the complex during an archaeological excavation more than a century ago has produced significant new insights into how the people of Carrowkeel perceived death and how they maintained and manifested social links with their ancestors. In addition to the rite of cremation, a complex postmortem burial practice is further attested by the presence of cut marks on several of the unburned bones, which indicate that the bodies of the dead were dismembered before they were placed in the tombs. It is argued that both cremation and dismemberment (and possible defleshing) may have been physical expressions of similar objectives, relating to excarnation and removal of flesh from the bodies of the deceased. Processing the bodies and thereby assisting the dead to transcend to an extra-bodily realm of existence may have been the main focus of the burial rite. The passage tombs at Carrowkeel should perhaps be viewed as places of curation, transformation, and regeneration of enduring ancestors that enabled both a physical and spiritual interaction with the dead and allowed for their omnipresence among the living

Rites of Passage: Mortuary Practice, Population Dynamics, and Chronology at the Carrowkeel Passage Tomb Complex, Co. Sligo, Ireland

]The first detailed investigation of the human remains from the Carrowkeel passage tomb complex since their excavation in 1911 has revealed several new and important insights about life, death, and mortuary practice in Neolithic Ireland. Osteological analysis provides the first conclusive proof for the occurrence of dismemberment of the dead at Irish passage tombs, practised contemporarily with cremation as one of a suite of funerary treatments. The research also highlights changes in burial tradition at the complex over the course of the Neolithic. Providing a chronology for these changes allows them to be linked to wider trends in monument construction, which may relate to changes in both land use and climate during the period. Multi-isotope analysis hints at the presence of non-local individuals among the interred and the possible existence of different food sourcing areas at the onset of the later Neolithic period. Preliminary results from ancient DNA sequencing of six individuals from Carrowkeel provide evidence for the genetic ancestry of Irish Neolithic populations, demonstrating their Anatolian origins and links along the Atlantic façade