POPULATION STUDIES OF QUALITY OF LIFE INDICATORS IN THE CITY OF KIZILURT

Aim. We studied quality of life indicators in the city of Kizilurt (Republic of Dagestan) by representative sampling of 1,354 people aged from18 to 86 years (785 women and 569 men). Methods. The study was performed using the SF-36 Health Survey in accordance with the requirements of the International Quality of Life Assessment Project. Results. As the study showed, with age there is a decrease in quality of life among both male and female population. The most marked age-related decline of population quality of life is marked by physical functioning scale. The average values of life quality indicators, studied for 8 scales SF-36, ranged from 59.4 (the scale of general health) to 80.5 (the scale of physical functioning). Quality of life of the male population is higher than that of the female on all rating scales of the survey. Thus, we revealed the biggest gender differences on the physical functioning scale, while the smallest on the social functioning scale. Conclusion. These population-based studies of life quality made possible to evaluate the effectiveness of the implementation of various medical and social and economic programs aimed at improving the quality of life and well-being. They can serve as indicators of the environmental component, significantly complementing the overall picture of environmental research

COMPUTER SIMULATION OF THE HEATING PROCESS AND THE DETERMINATION OF THE CALCULATED LOAD OF THE CONDUCTOR UNDER STOCHASTIC CHARACTER OF CURRENT CHANGE

In this article we propose an automated laboratory bench for the evaluation of the current and the study of the adequacy of this  mathematical model overheating of the wire relative to the  environment. Is developed the structural diagram of model  describing the overheating of the conductor relative to the  environment. The model consists of six blocks in which modeling operations are implemented: the simulation of the load  current, is given by the stochastic law; the  integration of the  corresponding differential equations; the definition of the calculated  currents and the output of simulation results. In developing a  computer model of heating of the conductor adopted a scheme of  thermal processes in the conductor, described in scientific  publications. The simulation was performed in Simulink

HEART RATE VARIABILITY IN PATIENTS WITH PREVIOUS Q-WAVE MYOCARDIAL INFARCTION IN DIFFERENT TREATMENT SCHEMES IN EARLY POSTINFARCTION PERIOD

Aim. To evaluate influence of various drug combinations on heart rate variability (HRV) in patients with previous Q-wave myocardial infarction (Q-MI) in outpatient period of rehabilitation.Material and methods. A total of 316 patients with previous Q-MI were randomized into three groups. Patients of the control group (n=103) received standard therapy (acetylsalicylic acid, enalapril, metoprolol, simvastatin) during 2 years after discharge from the hospital. Patients of the first studied group (n=107) were additionally treated with trimetazidine, and patients of the second group (n=106) received combined therapy with ramipril, carvedilol and trimetazidine. HRV parameters (derived from ECG 5-minute recording) were registered at the beginning of the study, 6 and 24 months after the beginning of the study.Results. HRV parameters improvement was more significant in the second group compared to the first and to control groups. In the second group LF increased from 223.8±56.2 to 734±90.9 мs2 (p<0.001), in the first group – from 217.8±54.3 to 713±88.1 мs2, and in control group – from 225.4±49.0 to 589±72.0 мs2. HF increase was also more significant in the second group: from 189.5±54.4 to 801±97.5 мs2 (p<0.001) compared to the first and to control groups: from 176.6±47.3 to 579±91.2 мs2 and from 180.9±50.4 to 487±83.4 мs2, respectively. SDNN rose from 27.8±3.2 to 52.4±4.4 ms (p<0.05) in the second group, from 27.4±2.7 to 41.2±3.8 ms in control group, and from 26.7±3.0 to 46.5±4.0 ms in the first group. RRNN increased from 664.5±99.0 to 833±98.7 ms (p<0.05) in the second group, from 676.2±85.3 to 793±87.6 ms in control group, and from 658.1±97.2 to 826±92.8 ms in the first group.Conclusion. Two-year treatment with enalapril and metoprolol as a part of standard therapy improves HRV parameters of Q-MI patients. Addition of trimetazidine to this combination leads to even more significant improvement of HRV parameters in postinfarction period. The most significant effect on the reduction of sympathetic nervous system activity, increase in parasympathetic nervous system activity as well as improvement of HRV parameters was observed in therapy with combination of trimetazidine, ramipril and carvedilol

HOLTER ECG MONITORING AND TREATMENT EFFECTIVENESS CONTROL IN PATIENTS AFTER MYOCARDIAL INFARCTION

In total, 316 patients after Q wave myocardial infarction (Q-MI) were randomised into 3 groups. For 6 months after discharge, the control group (n=103) received standard therapy (aspirin, enalapril, metoprolol, simvastatin). Group 1 (n=107) also received trimetazidine, and Group 2 (n=106) was administered ramipril, carvedilol, and trimetazidine. At baseline, 6 months and 2 years later, 24-hour Holter ECG monitoring was performed. The combination of ramipril, carvedilol, and trimetazidine (Group 2) was the most effective in prevention of pain and painless episodes of myocardial ischemia, as well as in reduction of supraventricular and ventricular extrasystolia incidence. The combination of enalapril, metoprolol, and trimetazidine (Group 1) was less effective than Group 2 treatment, but more effective than the therapy in the control group (enalapril, metoprolol, and standard therapy, without trimetazidine treatment)

STUDY OF QUALITY OF LIFE OF THE INHABITANTS OF THE MUNICIPALITY «KIZILYURT DISTRICT», REPUBLIC OF DAGESTAN

Abstract. Aim. We studied life quality indicators of the population in Kizilyurt district of Dagestan in a random representative sample of 4267 people (2378 women and 1889 men) aged between 17 and 96 years. Respondents were divided into 3 age groups (up to 35 years, 35-50 years and 50 years and older). Methods. The study was performed using a common health survey Medical Outcomes Study-Short Form-36 (SF-36) in accordance with the requirements of the International Quality of Life Assessment Project (IQOLA). Results. We conducted a comparative analysis of age dynamics of population quality of life, as well as the male and female population of the study sample. The highest quality of life indicators are found on the scales of social (SF) and physical functioning (PF) – 76 and 76.8 points, respectively, the lowest on the scale of general health – 58.7. In general, with aging, there is a decrease of life quality among both male and female population. The most marked age-related changes are observed on the scale of role-physical functioning and physical functioning – 32 and 28.4% respectively and the least marked on the scale of mental health – 13%. The value of the integral index of quality of life in population-based study in Kizilyurt district of Dagestan was 551.7. Conclusion. The research findings might be used in planning, developing and evaluating the effectiveness of various reforms, health and socio-economic programs being implemented in the region as well as to improve the quality of life and well-being