280 research outputs found

    End of life dental service utilization by geriatric patients in a long-term care setting

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    OBJECTIVE: To understand dental service utilization by frail older adults residing in a long-term care (LTC) setting in the last two years of their life. To understand the types of dental services utilized by this demographic, the frequency of utilization and determine the characteristics that may be predictors of ‘higher dental service utilization’. METHODS: A retrospective cohort study was conducted by an electronic chart review of all LTC patients at two sites who died between 11/1/2014 - 12/30/2016 and had a dental visit in the two-year period prior to death, resulting in a sample of 369 patients. Based on the number of dental appointments attended prior to death, the patients were categorized into five groups: 0,1-2,3-5,6-9 and10 or more appointments. A multivariate logistic regression model was created to identify the factors associated with higher dental service utilization. RESULT: The study found that 84% of patients who died in the study period, utilized on-site dental services in the last two years of their life. Approximately 66% had 3 or more dental appointments. Diagnostic and preventive procedures were most commonly utilized (utilized by 81% and 73% of patients respectively). Multivariate analysis suggested that dentate patients and patients wearing removable dental prosthesis were about 7 and 12 times more likely respectively to have a higher utilization of dental services (OR=6.5 and OR=11.7). Medicaid beneficiaries were more likely (OR=1.9) to have a higher utilization of dental services than the others. CONCLUSIONS: This study showed that a large percentage of frail older adults utilized dental services even in the last years of their lives when given access to these services. As people are living longer and retaining their teeth longer, there is a rising need and subsequent demand for end-of-life dental services. Certain administrative and policy implementation strategies need to be developed to provide dental services to LTC patients in the last years of their lives

    A Comparative Study Of The Primary Vascular System Of Conifers. I. Genera With Helical Phyllotaxis

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141889/1/ajb207398.pd

    Management of neonatal central nervous system viral infections: Knowledge gaps and research priorities

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    Congenital CMV, enteroviruses, human parechovirus and herpes simplex virus are all common causes of severe central nervous system (CNS) infection in neonates. The introduction of screening (i.e. newborn hearing screening programme), integration of molecular syndromic testing (i.e. multiplex polymerase chain reaction assays) and increase in sexually transmitted infections (i.e. anogenital herpes) have contributed to increases in each of these infections over the last decade. However, therapeutic options are highly limited in part due to the lack of epidemiological data informing trials. This review will describe our current understanding of the clinical burden and epidemiology of these severe neonatal CNS infections, outline the novel antiviral and vaccines in the pipeline and suggest future research studies which could help develop new therapeutics

    Fast Graph Convolutional Recurrent Neural Networks

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    This paper proposes a Fast Graph Convolutional Neural Network (FGRNN) architecture to predict sequences with an underlying graph structure. The proposed architecture addresses the limitations of the standard recurrent neural network (RNN), namely, vanishing and exploding gradients, causing numerical instabilities during training. State-of-the-art architectures that combine gated RNN architectures, such as Long Short-Term Memory (LSTM) and Gated Recurrent Unit (GRU) with graph convolutions are known to improve the numerical stability during the training phase, but at the expense of the model size involving a large number of training parameters. FGRNN addresses this problem by adding a weighted residual connection with only two extra training parameters as compared to the standard RNN. Numerical experiments on the real 3D point cloud dataset corroborates the proposed architecture.Comment: 5 pages.Submitted to Asilomar Conference on Signals, Systems, and Computer

    Indirect effects of cytomegalovirus infection: Implications for vaccine development

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    Development of a cytomegalovirus (CMV) vaccine is a high priority due to its significant global impact—contributing to mortality in immunosuppressed individuals, neurodevelopmental delay in infected neonates and non-genetic sensorineural hearing loss. The impact of CMV on the general population has been less well studied; however, a wide range of evidence indicates that CMV may increase the risk of atherosclerosis, cancer, immunosenescence, and progression of tuberculosis (TB) and human immunodeficiency virus. Due to the high seroprevalence of CMV worldwide, any modulation of risk by CMV is likely to have a significant impact on the epidemiology of these diseases. This review will evaluate how CMV may cause morbidity and mortality outside of the neonatal and immunosuppressed populations and consider the potential impact of a CMV vaccine on these outcomes

    A Comparative Study Of The Primary Vascular System Of Conifers. Iii. Stelar Evolution In Gymnosperms

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141141/1/ajb207400.pd
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