62 research outputs found
Utilization of inorganic industrial wastes in producing construction ceramics. Review of Russian experience for the years 2000β2015
Β© 2016 Elsevier LtdThis paper analyzes the significant scientific publications worldwide for the last 15Β years concerning construction ceramics (predominantly brick) made with various inorganic industrial wastes added to the ceramic raw material for the improvement of properties and for eco-friendly disposal. The information gap resulting from the lack of mentions of the Russian publications on this subject in English-language reviews is filled. The paper includes brief summaries of 34 dissertations and 29 patents issued in Russia since 2000. The waste additives described in these summaries are grouped by origin type (mining industry waste, ore enrichment waste, metallurgical waste, sludge, ashes, cullet, large-capacity building wastes and waste from various chemical production processes) with the ceramic mixture compositions, molding and firing conditions, final strength, water absorption and other parameters of the final ceramic samples reported. Russian scientists have expanded the nomenclature of each group of wastes significantly upon addition to the list described in English-language reviews for 2000β2015. References to the recent Russian developments in the field of ecological management in ceramic industry are provided
Magnetic properties of (La<inf>0.7</inf>Sr<inf>0.3</inf>MnO<inf>3</inf>)<inf>x</inf>(CaCu<inf>3</inf>Ti<inf>4</inf>O<inf>12</inf>)<inf>1βx</inf>nanostructured composites
Β© 2017 Elsevier B.V. (La 0.7 Sr 0.3 MnO 3 ) x (CaCu 3 Ti 4 O 12 ) 1βx (0.01Β β€Β xΒ β€Β 0.3) nanostructured composites with La 0.7 Sr 0.3 MnO 3 (LSMO) microinclusions in CaCu 3 Ti 4 O 12 (CCTO) matrix were synthesized using a solid state method. The structural and microstructural details were studied by X-ray diffraction (XRD), X-ray fluorescence (XFA), scaning electron microscope (SEM) and transmission electron microscope (TEM) techniques. The magnetic properties were studied by electron spin resonance (ESR) and magnetometry methods. In the concentration range 0.01Β < Β xΒ < Β 0.1 physical properties of composites differ from the properties of the individual components CCTO or LSMO. The Curie temperature of the ferromagnetic phase for all concentrations is T C Β =Β 315Β K, that is less at 50Β K than in pure LSMO. The Weiss constant of the paramagnetic phase has the strong concentration dependance. The observed mutual influence on the magnetic properties of both components can be tentatively attributed to the interface exchange interactions between them, hinting a possible magnetic proximity effect
Ultrasound-assisted extrusion of construction ceramic samples
Β© 2017 Elsevier Ltd and Techna Group S.r.l.The conditions for a decrease in friction during ceramic brick production between a mixture and an extruder die under the influence of 20β30Β kHz ultrasound applied to the die are calculated. An optimum design of a die used to mold 30Β mm diameter cylindrical samples with a resonance in this frequency range is selected using computer modeling. From the results, a titanium die is fabricated and tested on a Verdesβ050 (Spain) laboratory extruder using an ultrasonic magnetostrictive transducer with a power of 1.5Β kW (Inlab-Ultrazvuk, Russia). A 12% reduction in extrusion pressure, a 20% acceleration of molding and a positive influence on the properties of the ceramics were found. The surface of the ceramic samples was covered by craters with diameters of approximately 10Β Β΅m due to the boiling of water, and the porosity of the main body of the samples decreased. This technique prevents the undesirable rapid drying of the surface when the samples exit the die and stabilizes the strength of the fired samples. The color remained unchanged, the water absorption decreased, the density, strength and resistance to frost increased. Ultrasonic extrusion increased the accuracy of the strength tests of construction ceramics, indicating the prospect of ultrasonic die development for industrial extruders for bricks, facing tiles and roof tiles
Markers of kidney damage in the diagnosis of infectious-inflammatory in patients with urolithiasis after contact ureterolithotripsy
Currently one of the main methods of treatment of patients with ureteral stones is contact ureterolithotripsy (CUlT). despite the high effectiveness of the method, the problem of early detection and prevention of exacerbation of inflammatory complications of nephrolithiasis remains urgent. To improve the diagnosis of pyelonephritis after CUlT in patients with urolithiasis, a study of the diagnostic efficacy of neutrophil gelatinase-associated lipocalin (NGAl), cystatin C, Ξ²2-microglobulin, and interleukin-18 was performed in 123 patients with ureteral stones. The greatest value in preoperative diagnostics of pyelonephritis was demonstrated for serum NGAl of blood, urine NGAl, and urine Ξ²2-microglobulin. The most significant increase during early term (2 hours) after CUlT was observed for urine Ξ²2-microglobulin and Il-18. The concentration of urine NGAl among all the studied markers remained elevated for a relatively longer period.ΠΠ΄Π½ΠΈΠΌ ΠΈΠ· ΠΎΡΠ½ΠΎΠ²Π½ΡΡ
ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ ΠΊΠ°ΠΌΠ½ΡΠΌΠΈ ΠΌΠΎΡΠ΅ΡΠΎΡΠ½ΠΈΠΊΠΎΠ² Π² Π½Π°ΡΡΠΎΡΡΠ΅Π΅ Π²ΡΠ΅ΠΌΡ ΡΠ²Π»ΡΠ΅ΡΡΡ ΡΡΠ°Π½ΡΡΡΠ΅ΡΡΠ°Π»ΡΠ½Π°Ρ ΠΊΠΎΠ½ΡΠ°ΠΊΡΠ½Π°Ρ ΡΡΠ΅ΡΠ΅ΡΠΎΠ»ΠΈΡΠΎΡΡΠΈΠΏΡΠΈΡ (ΠΠΠ’). ΠΠ΅ΡΠΌΠΎΡΡΡ Π½Π° Π²ΡΡΠΎΠΊΡΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΌΠ΅ΡΠΎΠ΄Π°, ΠΎΡΡΠ°Π΅ΡΡΡ Π°ΠΊΡΡΠ°Π»ΡΠ½ΠΎΠΉ ΠΏΡΠΎΠ±Π»Π΅ΠΌΠ° ΡΠ°Π½Π½Π΅Π³ΠΎ Π²ΡΡΠ²Π»Π΅Π½ΠΈΡ ΠΈ ΠΏΡΠ΅Π΄ΡΠΏΡΠ΅ΠΆΠ΄Π΅Π½ΠΈΡ ΠΎΠ±ΠΎΡΡΡΠ΅Π½ΠΈΡ Π²ΠΎΡΠΏΠ°Π»ΠΈΡΠ΅Π»ΡΠ½ΡΡ
ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠΉ Π½Π΅ΡΡΠΎΠ»ΠΈΡΠΈΠ°Π·Π°. Π‘ ΡΠ΅Π»ΡΡ ΡΠ»ΡΡΡΠ΅Π½ΠΈΡ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠΈ ΠΏΠΈΠ΅Π»ΠΎΠ½Π΅ΡΡΠΈΡΠ° ΠΏΠΎΡΠ»Π΅ ΠΠΠ’ Ρ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ ΡΡΠΎΠ»ΠΈΡΠΈΠ°Π·ΠΎΠΌ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ Π»ΠΈΠΏΠΎΠΊΠ°Π»ΠΈΠ½Π°, Π°ΡΡΠΎΡΠΈΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ Ρ ΠΆΠ΅Π»Π°ΡΠΈΠ½Π°Π·ΠΎΠΉ Π½Π΅ΠΉΡΡΠΎΡΠΈΠ»ΠΎΠ² (ΠΠΠΠ), ΡΠΈΡΡΠ°ΡΠΈΠ½Π° Π‘, Ξ²2-ΠΌΠΈΠΊΡΠΎΠ³Π»ΠΎΠ±ΡΠ»ΠΈΠ½Π° ΠΈ ΠΈΠ½ΡΠ΅ΡΠ»Π΅ΠΉΠΊΠΈΠ½Π°-18 ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΎ Ρ 123 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ ΠΊΠ°ΠΌΠ½ΡΠΌΠΈ ΠΌΠΎΡΠ΅ΡΠΎΡΠ½ΠΈΠΊΠΎΠ². ΠΠ°ΠΈΠ±ΠΎΠ»ΡΡΠ°Ρ ΡΠ΅Π½Π½ΠΎΡΡΡ Π² Π΄ΠΎΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠ΅ ΠΏΠΈΠ΅Π»ΠΎΠ½Π΅ΡΡΠΈΡΠ° ΠΏΡΠΎΠ΄Π΅ΠΌΠΎΠ½ΡΡΡΠΈΡΠΎΠ²Π°Π½Π° Π΄Π»Ρ ΠΠΠΠ ΠΊΡΠΎΠ²ΠΈ, ΠΠΠΠ ΠΈ Ξ²2ΠΌΠΈΠΊΡΠΎΠ³Π»ΠΎΠ±ΡΠ»ΠΈΠ½Π° ΠΌΠΎΡΠΈ. Π‘Π°ΠΌΠΎΠ΅ Π·Π½Π°ΡΠΈΡΠ΅Π»ΡΠ½ΠΎΠ΅ ΠΏΠΎΠ²ΡΡΠ΅Π½ΠΈΠ΅ Π² ΡΠ°Π½Π½ΠΈΠ΅ ΡΡΠΎΠΊΠΈ (ΡΠ΅ΡΠ΅Π· 2 ΡΠ°ΡΠ°) ΠΏΠΎΡΠ»Π΅ ΠΠΠ’ Π½Π°Π±Π»ΡΠ΄Π°Π»ΠΎΡΡ Π΄Π»Ρ Ξ²2ΠΌΠΈΠΊΡΠΎΠ³Π»ΠΎΠ±ΡΠ»ΠΈΠ½Π° ΠΈ ΠΠ-18 ΠΌΠΎΡΠΈ. ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΡ ΠΠΠΠ ΠΌΠΎΡΠΈ ΡΡΠ΅Π΄ΠΈ Π²ΡΠ΅Ρ
ΠΈΠ·ΡΡΠ΅Π½Π½ΡΡ
ΠΌΠ°ΡΠΊΠ΅ΡΠΎΠ² ΠΎΡΡΠ°Π²Π°Π»Π°ΡΡ ΠΏΠΎΠ²ΡΡΠ΅Π½Π½ΠΎΠΉ ΡΡΠ°Π²Π½ΠΈΡΠ΅Π»ΡΠ½ΠΎ Π½Π° Π±ΠΎΠ»Π΅Π΅ Π΄Π»ΠΈΡΠ΅Π»ΡΠ½ΡΠΉ ΡΡΠΎΠΊ
ΠΡΠΎΡΠΈΠ»Π°ΠΊΡΠΈΠΊΠ° ΠΏΠΎΡΠ»Π΅ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΡΡ ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠΉ ΠΏΠΎΡΠ»Π΅ ΡΠΎΠ±ΠΎΡ-Π°ΡΡΠΈΡΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΉ ΡΡΠ°Π½ΡΠ°Π±Π΄ΠΎΠΌΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΏΡΠ΅ΠΏΠ΅ΡΠΈΡΠΎΠ½Π΅Π°Π»ΡΠ½ΠΎΠΉ ΠΏΠ»Π°ΡΡΠΈΠΊΠΈ: ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΠΉ ΡΠ»ΡΡΠ°ΠΉ
Introduction. Inguinal hernia repair is one of the most common elective surgeries today. In our clinic, the majority of inguinal hernia repairs are performed laparoscopically. The most frequent complication after transabdominal preperitoneal inguinal hernia repair is postoperative seroma.Materials and methods. A 35-year-old patient C. with a right-sided inguinal hernia sought medical care in our clinic. He underwent robot-assisted TAPP with fluorescence lymphography using indocyanine green (ICG).Results and discussion. The present paper describes the possible relationship between intraoperative damage of the lymphatic vessels within the spermatic cord induced by robot-assisted transabdominal preperitoneal inguinal hernia repair and postoperative development of inguinal seroma. 5 mg/ml of indocyanine green was injected into the testicle on the side with the hernial bulge to visualize the lymphatic vessels. In this case such procedure is safe and feasible. Due to the tight fusion of the hernia sac with two visualized lymphatic vessels, they were excised during surgery. In the early postoperative period, an ultrasound scan revealed a subclinical seroma in the inguinal region of approximately 10 ml.Conclusion. A case series of ICG fluorescence lymphography during robot-assisted TAPP should be performed further to elucidate the relationship between lymphatic vessel damage and hydrocele.ΠΠ²Π΅Π΄Π΅Π½ΠΈΠ΅. ΠΠ΄Π½ΠΎΠΉ ΠΈΠ· Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ ΡΠ°ΡΡΠΎ Π²ΡΠΏΠΎΠ»Π½ΡΠ΅ΠΌΡΡ
ΠΏΠ»Π°Π½ΠΎΠ²ΡΡ
ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΉ Π½Π° ΡΠ΅Π³ΠΎΠ΄Π½Ρ ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΏΠ°Ρ
ΠΎΠ²ΠΎΠ΅ Π³ΡΡΠΆΠ΅ΡΠ΅ΡΠ΅Π½ΠΈΠ΅. Π Π½Π°ΡΠ΅ΠΉ ΠΊΠ»ΠΈΠ½ΠΈΠΊΠ΅ Π±Γ³Π»ΡΡΠ°Ρ ΡΠ°ΡΡΡ ΠΏΠ°Ρ
ΠΎΠ²ΡΡ
Π³ΡΡΠΆΠ΅ΡΠ΅ΡΠ΅Π½ΠΈΠΉ Π²ΡΠΏΠΎΠ»Π½ΡΠ΅ΡΡΡ Π»Π°ΠΏΠ°ΡΠΎΡΠΊΠΎΠΏΠΈΡΠ΅ΡΠΊΠΈΠΌ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ. ΠΠ°ΠΈΠ±ΠΎΠ»Π΅Π΅ ΡΠ°ΡΡΡΠΌ ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠ΅ΠΌ ΠΏΠΎΡΠ»Π΅ ΡΡΠ°Π½ΡΠ°Π±Π΄ΠΎΠΌΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΏΡΠ΅ΠΏΠ΅ΡΠΈΡΠΎΠ½Π΅Π°Π»ΡΠ½ΠΎΠΉ ΠΏΠ»Π°ΡΡΠΈΠΊΠΈ ΠΏΠ°Ρ
ΠΎΠ²ΡΡ
Π³ΡΡΠΆ ΡΠ²Π»ΡΠ΅ΡΡΡ Π²ΠΎΠ·Π½ΠΈΠΊΠ½ΠΎΠ²Π΅Π½ΠΈΠ΅ ΠΏΠΎΡΠ»Π΅ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΡΡ
ΡΠ΅ΡΠΎΠΌ.ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. Π Π½Π°ΡΠ΅ ΠΎΡΠ΄Π΅Π»Π΅Π½ΠΈΠ΅ ΠΎΠ±ΡΠ°ΡΠΈΠ»ΡΡ ΠΏΠ°ΡΠΈΠ΅Π½Ρ Π‘. 35 Π»Π΅Ρ Ρ ΠΏΡΠ°Π²ΠΎΡΡΠΎΡΠΎΠ½Π½Π΅ΠΉ ΠΏΠ°Ρ
ΠΎΠ²ΠΎΠΉ Π³ΡΡΠΆΠ΅ΠΉ. ΠΠΌΡ Π±ΡΠ»Π° Π²ΡΠΏΠΎΠ»Π½Π΅Π½Π° ΡΠΎΠ±ΠΎΡ-Π°ΡΡΠΈΡΡΠΈΡΠΎΠ²Π°Π½Π½Π°Ρ Π’ΠΠ Π Ρ ΡΠ»ΡΠΎΡΠ΅ΡΡΠ΅Π½ΡΠ½ΠΎΠΉ Π»ΠΈΠΌΡΠΎΠ³ΡΠ°ΡΠΈΠ΅ΠΉ Ρ ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ΠΌ ΠΈΠ½Π΄ΠΎΡΠΈΠ°Π½ΠΈΠ½Π° Π·Π΅Π»Π΅Π½ΠΎΠ³ΠΎ (ICG).Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΈ ΠΎΠ±ΡΡΠΆΠ΄Π΅Π½ΠΈΠ΅. Π ΡΡΠ°ΡΡΠ΅ ΠΎΠΏΠΈΡΡΠ²Π°Π΅ΡΡΡ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½Π°Ρ ΡΠ²ΡΠ·Ρ ΠΌΠ΅ΠΆΠ΄Ρ ΠΈΠ½ΡΡΠ°ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ ΡΡΠ°Π²ΠΌΠΎΠΉ Π»ΠΈΠΌΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠΎΡΡΠ΄ΠΎΠ² Π² ΡΠΎΡΡΠ°Π²Π΅ ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠ³ΠΎ ΠΊΠ°Π½Π°ΡΠΈΠΊΠ° Π²ΠΎ Π²ΡΠ΅ΠΌΡ Π²ΡΠΏΠΎΠ»Π½Π΅Π½ΠΈΡ ΡΠΎΠ±ΠΎΡ-Π°ΡΡΠΈΡΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΉ ΡΡΠ°Π½ΡΠ°Π±Π΄ΠΎΠΌΠΈΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΏΡΠ΅ΠΏΠ΅ΡΠΈΡΠΎΠ½Π΅Π°Π»ΡΠ½ΠΎΠΉ ΠΏΠ»Π°ΡΡΠΈΠΊΠΈ ΠΏΠ°Ρ
ΠΎΠ²ΠΎΠΉ Π³ΡΡΠΆΠΈ ΠΈ ΡΠ°Π·Π²ΠΈΡΠΈΠ΅ΠΌ ΡΠ΅ΡΠΎΠΌ ΠΏΠ°Ρ
ΠΎΠ²ΠΎΠΉ ΠΎΠ±Π»Π°ΡΡΠΈ Π² ΠΏΠΎΡΠ»Π΅ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΌ ΠΏΠ΅ΡΠΈΠΎΠ΄Π΅. Π‘ ΡΠ΅Π»ΡΡ Π²ΠΈΠ·ΡΠ°Π»ΠΈΠ·Π°ΡΠΈΠΈΠΈ Π»ΠΈΠΌΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠΎΡΡΠ΄ΠΎΠ² Π±ΡΠ» ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ ΠΏΡΠ΅ΠΏΠ°ΡΠ°Ρ ΠΈΠ½Π΄ΠΎΡΠΈΠ°Π½ΠΈΠ½ Π·Π΅Π»Π΅Π½ΡΠΉ 5 ΠΌΠ³/ΠΌΠ», ΠΊΠΎΡΠΎΡΡΠΉ Π±ΡΠ» Π²Π²Π΅Π΄Π΅Π½ Π² ΡΠΈΡΠΊΠΎ Π½Π° ΡΡΠΎΡΠΎΠ½Π΅ Π³ΡΡΠΆΠ΅Π²ΠΎΠ³ΠΎ Π²ΡΠΏΡΡΠΈΠ²Π°Π½ΠΈΡ. ΠΠ°Π½Π½Π°Ρ ΠΏΡΠΎΡΠ΅Π΄ΡΡΠ° Π±Π΅Π·ΠΎΠΏΠ°ΡΠ½Π° ΠΈ Π²ΡΠΏΠΎΠ»Π½ΠΈΠΌΠ° Π² Π΄Π°Π½Π½ΠΎΠΌ ΡΠ»ΡΡΠ°Π΅. Π ΡΠ²ΡΠ·ΠΈ Ρ ΠΏΠ»ΠΎΡΠ½ΡΠΌ ΡΡΠ°ΡΠ΅Π½ΠΈΠ΅ΠΌ Π³ΡΡΠΆΠ΅Π²ΠΎΠ³ΠΎ ΠΌΠ΅ΡΠΊΠ° ΠΈ Π΄Π²ΡΡ
Π²ΠΈΠ·ΡΠ°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
Π»ΠΈΠΌΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠΎΡΡΠ΄ΠΎΠ² Π² Ρ
ΠΎΠ΄Π΅ ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΈ ΠΏΠΎΡΠ»Π΅Π΄Π½ΠΈΠ΅ Π±ΡΠ»ΠΈ ΠΈΡΡΠ΅ΡΠ΅Π½Ρ. Π ΡΠ°Π½Π½Π΅ΠΌ ΠΏΠΎΡΠ»Π΅ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΌ ΠΏΠ΅ΡΠΈΠΎΠ΄Π΅ Ρ ΠΏΠΎΠΌΠΎΡΡΡ ΡΠ»ΡΡΡΠ°Π·Π²ΡΠΊΠΎΠ²ΠΎΠ³ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π²ΡΡΠ²Π»Π΅Π½Π° ΡΡΠ±ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠ°Ρ ΡΠ΅ΡΠΎΠΌΠ° Π² ΠΏΠ°Ρ
ΠΎΠ²ΠΎΠΉ ΠΎΠ±Π»Π°ΡΡΠΈ ΠΎΠ±ΡΠ΅ΠΌΠΎΠΌ ΠΎΠΊΠΎΠ»ΠΎ 10 ΠΌΠ».ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. Π ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅ ΡΠ»Π΅Π΄ΡΡΡΠ΅Π³ΠΎ ΡΠ°Π³Π° Π΄Π»Ρ Π²ΡΡΡΠ½Π΅Π½ΠΈΡ ΡΠ²ΡΠ·ΠΈ ΠΌΠ΅ΠΆΠ΄Ρ ΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π΅Π½ΠΈΠ΅ΠΌ Π»ΠΈΠΌΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠΎΡΡΠ΄ΠΎΠ² ΠΈ Π²ΠΎΠ΄ΡΠ½ΠΊΠΎΠΉ ΡΠΈΡΠΊΠ° ΡΠ»Π΅Π΄ΡΠ΅Ρ ΠΏΡΠΎΠ²Π΅ΡΡΠΈ ΡΠ΅ΡΠΈΡ ΡΠ»ΡΡΠ°Π΅Π² ΡΠ»ΡΠΎΡΠ΅ΡΡΠ΅Π½ΡΠ½ΠΎΠΉ Π»ΠΈΠΌΡΠΎΠ³ΡΠ°ΡΠΈΠΈ ICG Π²ΠΎ Π²ΡΠ΅ΠΌΡ ΡΠΎΠ±ΠΎΡ-Π°ΡΡΠΈΡΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΉ Π’ΠΠ Π
Robot-assisted pelvic evisceration for locally advanced cervical cancer. First experience
Pelvic evacuation in recent years has ceased to be used as a palliative method and has proved to be an effective method of surgical treatment of locally advanced pelvic tumors. Performing these operations with minimally invasive methods helps to reduce the number of postoperative complications and improve the quality of life. Purpose of the study. demonstrate the feasibility of performing robot-assisted pelvic evisceration and compare perioperative parameters with the experience of open pelvic eviscerations. Materials and methods. A 44-year-old woman with progressive local advanced cervical cancer, with a complication of the tumor process, presented by bilateral hydronephrosis. The patient was provided with an anterior robot-assisted PE with the formation ileoconduit by the Brikker method. Results. The total operation time was 515 min, the time in the console was 430 min. The estimated loss of blood was 600 ml, and the stay in the intensive care unit (ICU) - 1 day, the patient was discharged on the 7th day after the operationΠΠ²Π΅Π΄Π΅Π½ΠΈΠ΅. ΠΠ²ΠΈΡΡΠ΅ΡΠ°ΡΠΈΡ ΠΌΠ°Π»ΠΎΠ³ΠΎ ΡΠ°Π·Π° Π² ΠΏΠΎΡΠ»Π΅Π΄Π½ΠΈΠ΅ Π³ΠΎΠ΄Ρ ΠΏΠ΅ΡΠ΅ΡΡΠ°Π»Π° ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°ΡΡΡΡ Π² ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅ ΠΏΠ°Π»Π»ΠΈΠ°ΡΠΈΠ²Π½ΠΎΠ³ΠΎ ΠΌΠ΅ΡΠΎΠ΄Π° ΠΈ Π·Π°ΡΠ΅ΠΊΠΎΠΌΠ΅Π½Π΄ΠΎΠ²Π°Π»Π° ΡΠ΅Π±Ρ ΠΊΠ°ΠΊ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΡΠΉ ΠΌΠ΅ΡΠΎΠ΄ Ρ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΌΠ΅ΡΡΠ½ΠΎ-ΡΠ°ΡΠΏΡΠΎΡΡΡΠ°Π½Π΅Π½Π½ΡΡ
ΠΎΠΏΡΡ
ΠΎΠ»Π΅ΠΉ ΠΌΠ°Π»ΠΎΠ³ΠΎ ΡΠ°Π·Π°. ΠΡΠΏΠΎΠ»Π½Π΅Π½ΠΈΠ΅ ΡΡΠΈΡ
ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΉ Ρ ΠΏΠΎΠΌΠΎΡΡΡ ΠΌΠΈΠ½ΠΈΠΌΠ°Π»ΡΠ½ΠΎ ΠΈΠ½Π²Π°Π·ΠΈΠ²Π½ΡΡ
ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΠΏΠΎΠΌΠΎΠ³Π°Π΅Ρ ΡΠ½ΠΈΠ·ΠΈΡΡ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ ΠΏΠΎΡΠ»Π΅ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΡΡ
ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠΉ ΠΈ ΡΠ»ΡΡΡΠΈΡΡ ΠΊΠ°ΡΠ΅ΡΡΠ²ΠΎ ΠΆΠΈΠ·Π½ΠΈ. Π¦Π΅Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ. ΠΡΠΎΠ΄Π΅ΠΌΠΎΠ½ΡΡΡΠΈΡΠΎΠ²Π°ΡΡ ΡΠ΅Π»Π΅ΡΠΎΠΎΠ±ΡΠ°Π·Π½ΠΎΡΡΡ Π²ΡΠΏΠΎΠ»Π½Π΅Π½ΠΈΡ ΡΠΎΠ±ΠΎΡΠ°ΡΡΠΈΡΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΉ ΡΠ²ΠΈΡΡΠ΅ΡΠ°ΡΠΈΠΈ ΠΌΠ°Π»ΠΎΠ³ΠΎ ΡΠ°Π·Π° ΠΈ ΡΡΠ°Π²Π½ΠΈΡΡ ΠΏΠ΅ΡΠΈΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΡΠ΅ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΠΈ Ρ ΠΎΠΏΡΡΠΎΠΌ ΠΎΡΠΊΡΡΡΡΡ
ΡΠ²ΠΈΡΡΠ΅ΡΠ°ΡΠΈΠΉ ΠΌΠ°Π»ΠΎΠ³ΠΎ ΡΠ°Π·Π°. ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. ΠΠ°ΡΠΈΠ΅Π½ΡΠΊΠ΅, 44-Π»Π΅ΡΠ½Π΅ΠΉ ΠΆΠ΅Π½ΡΠΈΠ½Π΅ Ρ ΠΏΡΠΎΠ³ΡΠ΅ΡΡΠΈΡΡΡΡΠΈΠΌ ΠΌΠ΅ΡΡΠ½ΠΎ-ΡΠ°ΡΠΏΡΠΎΡΡΡΠ°Π½Π΅Π½Π½ΡΠΌ ΡΠ°ΠΊΠΎΠΌ ΡΠ΅ΠΉΠΊΠΈ ΠΌΠ°ΡΠΊΠΈ, Ρ ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠ΅ΠΌ ΠΎΠΏΡΡ
ΠΎΠ»Π΅Π²ΠΎΠ³ΠΎ ΠΏΡΠΎΡΠ΅ΡΡΠ°, ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Π½ΡΠΌ Π΄Π²ΡΡΡΠΎΡΠΎΠ½Π½ΠΈΠΌ Π³ΠΈΠ΄ΡΠΎΠ½Π΅ΡΡΠΎΠ·ΠΎΠΌ, Π²ΡΠΏΠΎΠ»Π½Π΅Π½Π° ΠΏΠ΅ΡΠ΅Π΄Π½ΡΡ ΡΠΎΠ±ΠΎΡ-Π°ΡΡΠΈΡΡΠΈΡΠΎΠ²Π°Π½Π½Π°Ρ ΠΠΡ Ρ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ ΠΈΠ»Π΅ΠΎΠΊΠΎΠ½Π΄ΡΠΈΡΠ° ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ ΠΡΠΈΠΊΠΊΠ΅ΡΠ°. ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ. ΠΎΠ±ΡΠ΅Π΅ Π²ΡΠ΅ΠΌΡ ΡΠ°Π±ΠΎΡΡ ΡΠΎΡΡΠ°Π²Π»ΡΠ»ΠΎ 515 ΠΌΠΈΠ½, ΠΊΠΎΠ½ΡΠΎΠ»ΡΠ½ΠΎΠ΅ Π²ΡΠ΅ΠΌΡ ΡΠΎΡΡΠ°Π²Π»ΡΠ»ΠΎ 430 ΠΌΠΈΠ½. ΠΎΡΠ΅Π½Π΅Π½Π½Π°Ρ ΠΏΠΎΡΠ΅ΡΡ ΠΊΡΠΎΠ²ΠΈ ΡΠΎΡΡΠ°Π²Π»ΡΠ»Π° 600 ΠΌΠ», Π° ΠΏΡΠ΅Π±ΡΠ²Π°Π½ΠΈΠ΅ Π² ΠΎΡΠ΄Π΅Π»Π΅Π½ΠΈΠΈ ΡΠ΅Π°Π½ΠΈΠΌΠ°ΡΠΈΠΈ ΠΈ ΠΈΠ½ΡΠ΅Π½ΡΠΈΠ²Π½ΠΎΠΉ ΡΠ΅ΡΠ°ΠΏΠΈΠΈ β 1 ΡΡΡΠΊΠΈ, ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΊΠ° Π²ΡΠΏΠΈΡΠ°Π½Π° Π½Π° 7 ΡΡΡΠΊΠΈ ΠΏΠΎΡΠ»Π΅ ΠΎΠΏΠ΅ΡΠ°ΡΠΈ
ΠΠΎΠΌΠΏΠ»Π΅ΠΊΡ ΠΈΠ½Π΄ΠΎΡΠΈΠ°Π½ΠΈΠ½Π° Π·Π΅Π»Π΅Π½ΠΎΠ³ΠΎ Ρ Π°ΡΠ³ΠΈΠ½ΠΈΠ½-Π³Π»ΠΈΡΠΈΠ½-Π°ΡΠΏΠ°ΡΠ°Π³ΠΈΠ½ΠΎΠ²ΠΎΠΉ ΠΊΠΈΡΠ»ΠΎΡΠΎΠΉ ΠΊΠ°ΠΊ Π½ΠΎΠ²ΡΠΉ ΠΌΠ΅ΡΠΎΠ΄ ΠΈΠ½ΡΡΠ°ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ Π²ΠΈΠ·ΡΠ°Π»ΠΈΠ·Π°ΡΠΈΠΈ ΠΏΡΠΈ ΡΠ΅Π·Π΅ΠΊΡΠΈΠΈ ΡΠ°ΠΊΠ° ΠΌΠΎΡΠ΅Π²ΠΎΠ³ΠΎ ΠΏΡΠ·ΡΡΡ
Introduction. Bladder cancer is one of the most common malignancies in humans, causing significant economic and social damage. In the connection, it is proposed to use a highly sensitive bladder cancer detection method, which also detects residual tumours. Additionally, the method can be used to determine the boundaries of the bladder tumour, namely through intraoperative fluorescence molecular imaging. The target agent was synthesised earlier with indocyanine green-arginine-glycine-aspartic acid, which is an integrin avΓ3-targeted in in vitro and in vivo bladder cancer models.Materials and methods. The toxicity of indocyanine green-arginine-glycine-aspartic acid (Agac-IG) was measured using the MTT-test. Urothelial carcinoma cell lines were introduced in Female BALB/nu and MB49 mice by means of tumour xenografts via injection in the back of the elbow area. Tumour growth was observed on a daily basis and tested by magnetic resonance imaging until it became suitable for in vivo experiments. Then, all the laboratory animals were divided into 2 groups: ig and AGAk-ig (150 ΞΌl, 0.2 mg/ml for all mice). Following this, the tumour was surgically removed. The removed tissue was subjected to a fluorescent microscopy on the basis of infrared-spectrum and histologic studies.Results. Operations carried out on subcutaneous and orthotopic mouse models under the control of fluorescent imaging using AGAk-IG demonstrate the effectiveness of using a targeted tumour sample to achieve consistent and accurate RMP-resection. Operations under the control of BIC-spectrometry have demonstrated that the proposed substance can effectively help surgeons to locate tumours, determine their edges and constantly check the presence of tumour residues during surgery.Conclusion. The findings demonstrated the high efficiency of AGAk-IG as a potential molecular fluorescent agent for tumour-specific intraoperative imaging in bladder cancer resection, as well as offering great potential for further clinical studies.ΠΠ²Π΅Π΄Π΅Π½ΠΈΠ΅. Π Π°ΠΊ ΠΌΠΎΡΠ΅Π²ΠΎΠ³ΠΎ ΠΏΡΠ·ΡΡΡ ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΎΠ΄Π½ΠΈΠΌ ΠΈΠ· Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ ΡΠ°ΡΠΏΡΠΎΡΡΡΠ°Π½Π΅Π½Π½ΡΡ
Π·Π»ΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΡ
Π½ΠΎΠ²ΠΎΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΠΉ, ΠΏΡΠΈΠ½ΠΎΡΡΡΠΈΡ
Π·Π½Π°ΡΠΈΡΠ΅Π»ΡΠ½ΡΠΉ ΡΠΊΠΎΠ½ΠΎΠΌΠΈΡΠ΅ΡΠΊΠΈΠΉ ΠΈ ΡΠΎΡΠΈΠ°Π»ΡΠ½ΡΠΉ ΡΡΠ΅ΡΠ± ΡΠ΅Π»ΠΎΠ²Π΅ΠΊΡ. ΠΠ»Ρ ΡΠ΅ΡΠ΅Π½ΠΈΡ Π΄Π°Π½Π½ΠΎΠΉ ΠΏΡΠΎΠ±Π»Π΅ΠΌΡ ΠΏΡΠ΅Π΄Π»ΠΎΠΆΠ΅Π½ΠΎ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ Π²ΡΡΠΎΠΊΠΎΡΡΠ²ΡΡΠ²ΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΠΌΠ΅ΡΠΎΠ΄Π° ΠΎΠ±Π½Π°ΡΡΠΆΠ΅Π½ΠΈΡ ΡΠ°ΠΊΠ° ΠΌΠΎΡΠ΅Π²ΠΎΠ³ΠΎ ΠΏΡΠ·ΡΡΡ, Π²ΡΡΠ²Π»Π΅Π½ΠΈΡ ΠΎΡΡΠ°ΡΠΎΡΠ½ΠΎΠΉ ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ ΠΈ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ Π³ΡΠ°Π½ΠΈΡ ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ ΠΌΠΎΡΠ΅Π²ΠΎΠ³ΠΎ ΠΏΡΠ·ΡΡΡ β ΠΈΠ½ΡΡΠ°ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ ΡΠ»ΡΠΎΡΠ΅ΡΡΠ΅Π½ΡΠ½ΠΎΠΉ ΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΠΎΠΉ Π²ΠΈΠ·ΡΠ°Π»ΠΈΠ·Π°ΡΠΈΠΈ. Π Π°Π½Π΅Π΅ Π½Π°ΠΌΠΈ ΡΠΈΠ½ΡΠ΅Π·ΠΈΡΠΎΠ²Π°Π½ ΡΠ°ΡΠ³Π΅ΡΠ½ΡΠΉ Π°Π³Π΅Π½Ρ β ΠΈΠ½Π΄ΠΎΡΠΈΠ°Π½ΠΈΠ½Π° Π·Π΅Π»Π΅Π½ΠΎΠ³ΠΎ-Π°ΡΠ³ΠΈΠ½ΠΈΠ½-Π³Π»ΠΈΡΠΈΠ½-Π°ΡΠΏΠ°ΡΠ°Π³ΠΈΠ½ΠΎΠ²Π°Ρ ΠΊΠΈΡΠ»ΠΎΡΠ°, ΠΊΠΎΡΠΎΡΠ°Ρ ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΈΠ½ΡΠ΅Π³ΡΠΈΠ½ avΓ3-ΡΠ΅Π»Π΅Π½Π°ΠΏΡΠ°Π²Π»Π΅Π½Π½ΠΎΠΉ Π² in vitro ΠΈ in vivo ΠΌΠΎΠ΄Π΅Π»ΡΡ
ΡΠ°ΠΊΠ° ΠΌΠΎΡΠ΅Π²ΠΎΠ³ΠΎ ΠΏΡΠ·ΡΡΡ.ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. Π’ΠΎΠΊΡΠΈΡΠ½ΠΎΡΡΡ ΠΈΠ½Π΄ΠΎΡΠΈΠ°Π½ΠΈΠ½Π° Π·Π΅Π»Π΅Π½ΠΎΠ³ΠΎ-Π°ΡΠ³ΠΈΠ½ΠΈΠ½Π°-Π³Π»ΠΈΡΠΈΠ½-Π°ΡΠΏΠ°ΡΠ°Π³ΠΈΠ½ΠΎΠ²ΠΎΠΉ ΠΊΠΈΡΠ»ΠΎΡΡ (ΠΠΠΠΊ-ΠΠ¦Π) Π±ΡΠ»Π° ΠΈΠ·ΠΌΠ΅ΡΠ΅Π½Π° Ρ ΠΏΠΎΠΌΠΎΡΡΡ ΠΠ’Π’-ΡΠ΅ΡΡΠ°. Π‘Π°ΠΌΠΊΠΈ BALB/nu ΠΈ ΠΊΠ»Π΅ΡΠΎΡΠ½ΡΠ΅ Π»ΠΈΠ½ΠΈΠΈ MB49 ΡΡΠΎΡΠ΅Π»ΠΈΠ°Π»ΡΠ½ΠΎΠΉ ΠΊΠ°ΡΡΠΈΠ½ΠΎΠΌΡ ΠΌΡΡΠΈ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π»ΠΈ Π΄Π»Ρ ΡΡΡΠ°Π½ΠΎΠ²ΠΊΠΈ ΠΎΠΏΡΡ
ΠΎΠ»Π΅Π²ΡΡ
ΠΊΡΠ΅Π½ΠΎΡΡΠ°Π½ΡΠΏΠ»Π°Π½ΡΠ°ΡΠΎΠ², ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ Π² Π·Π°Π΄Π½ΡΡ Π»ΠΎΠΊΡΠ΅Π²ΡΡ ΠΎΠ±Π»Π°ΡΡΡ. Π ΠΎΡΡ ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ Π½Π°Π±Π»ΡΠ΄Π°Π»ΡΡ Π΅ΠΆΠ΅Π΄Π½Π΅Π²Π½ΠΎ ΠΈ ΠΏΡΠΎΠ²Π΅ΡΡΠ»ΡΡ ΠΌΠ°Π³Π½ΠΈΡΠ½ΠΎ-ΡΠ΅Π·ΠΎΠ½Π°Π½ΡΠ½ΠΎΠΉ ΡΠΎΠΌΠΎΠ³ΡΠ°ΡΠΈΠ΅ΠΉ, ΠΏΠΎΠΊΠ° ΠΎΠ½ Π½Π΅ ΡΡΠ°Π½ΠΎΠ²ΠΈΠ»ΡΡ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄ΡΡΠΈΠΌ Π΄Π»Ρ ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠΎΠ² in vivo. ΠΠ°Π»Π΅Π΅ Π»Π°Π±ΠΎΡΠ°ΡΠΎΡΠ½ΡΠ΅ ΠΆΠΈΠ²ΠΎΡΠ½ΡΠ΅ Π±ΡΠ»ΠΈ ΡΠ°Π·Π΄Π΅Π»Π΅Π½Ρ Π½Π° 2 Π³ΡΡΠΏΠΏΡ: ΠΠ¦Π ΠΈ ΠΠΠΠΊ-ΠΠ¦Π (150 ΠΌΠΊΠ», 0,2 ΠΌΠ³/ΠΌΠ» Π΄Π»Ρ Π²ΡΠ΅Ρ
ΠΌΡΡΠ΅ΠΉ). ΠΠ°ΡΠ΅ΠΌ ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΎΡΡ Ρ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΡΠ΄Π°Π»Π΅Π½ΠΈΠ΅ ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ. Π£Π΄Π°Π»Π΅Π½Π½ΡΡ ΡΠΊΠ°Π½Ρ ΠΏΠΎΠ΄Π²Π΅ΡΠ³Π°Π»ΠΈ ΡΠ»ΡΠΎΡΠ΅ΡΡΠ΅Π½ΡΠ½ΠΎΠΉ ΠΌΠΈΠΊΡΠΎΡΠΊΠΎΠΏΠΈΠΈ Π½Π° ΠΎΡΠ½ΠΎΠ²Π΅ Π±Π»ΠΈΠΆΠ½Π΅Π²ΠΎΠ»Π½ΠΎΠ²ΠΎΠ³ΠΎ ΠΈΠ½ΡΡΠ°ΠΊΡΠ°ΡΠ½ΠΎΠ³ΠΎ ΡΠΏΠ΅ΠΊΡΡΠ° ΠΈ Π³ΠΈΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΌΡ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. ΠΠΏΠ΅ΡΠ°ΡΠΈΠΈ, ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½Π½ΡΠ΅ Π½Π° ΠΏΠΎΠ΄ΠΊΠΎΠΆΠ½ΠΎΠΉ ΠΈ ΠΎΡΡΠΎΡΠΎΠΏΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΌΡΡΠΈΠ½ΡΡ
ΠΌΠΎΠ΄Π΅Π»ΡΡ
ΠΏΠΎΠ΄ ΠΊΠΎΠ½ΡΡΠΎΠ»Π΅ΠΌ ΡΠ»ΡΠΎΡΠ΅ΡΡΠ΅Π½ΡΠ½ΠΎΠΉ Π²ΠΈΠ·ΡΠ°Π»ΠΈΠ·Π°ΡΠΈΠΈ Ρ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ ΠΠΠΠΊ-ΠΠ¦Π, Π΄Π΅ΠΌΠΎΠ½ΡΡΡΠΈΡΡΡΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΡ ΠΏΡΠΈΡΠ΅Π»ΡΠ½ΠΎΠΉ ΠΎΠΏΡΡ
ΠΎΠ»Π΅Π²ΠΎΠΉ ΠΏΡΠΎΠ±Ρ Π΄Π»Ρ Π΄ΠΎΡΡΠΈΠΆΠ΅Π½ΠΈΡ Π°ΠΊΠΊΡΡΠ°ΡΠ½ΠΎΠΉ ΠΈ ΡΠΎΡΠ½ΠΎΠΉ Π ΠΠ ΡΠ΅Π·Π΅ΠΊΡΠΈΠΈ. ΠΠΏΠ΅ΡΠ°ΡΠΈΠΈ ΠΏΠΎΠ΄ ΠΊΠΎΠ½ΡΡΠΎΠ»Π΅ΠΌ ΠΠΠ-ΡΠΏΠ΅ΠΊΡΡΠΎΠΌΠ΅ΡΡΠΈΠΈ ΠΏΡΠΎΠ΄Π΅ΠΌΠΎΠ½ΡΡΡΠΈΡΠΎΠ²Π°Π»ΠΈ, ΡΡΠΎ ΠΏΡΠ΅Π΄Π»Π°Π³Π°Π΅ΠΌΠΎΠ΅ Π²Π΅ΡΠ΅ΡΡΠ²ΠΎ ΠΌΠΎΠΆΠ΅Ρ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎ ΠΏΠΎΠΌΠΎΡΡ Ρ
ΠΈΡΡΡΠ³Π°ΠΌ Π½Π°ΠΉΡΠΈ ΠΎΠΏΡΡ
ΠΎΠ»Ρ, ΠΎΠΏΡΠ΅Π΄Π΅Π»ΠΈΡΡ ΠΊΡΠ°ΠΉ ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ ΠΈ ΠΏΠΎΡΡΠΎΡΠ½Π½ΠΎ ΠΏΡΠΎΠ²Π΅ΡΡΡΡ Π½Π°Π»ΠΈΡΠΈΠ΅ ΠΎΡΡΠ°ΡΠΊΠΎΠ² ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ Π²ΠΎ Π²ΡΠ΅ΠΌΡ ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΈ.ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. Π’Π°ΠΊΠΈΠΌ ΠΎΠ±ΡΠ°Π·ΠΎΠΌ, ΠΏΠΎ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ°ΠΌ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΠΏΡΠΎΠ΄Π΅ΠΌΠΎΠ½ΡΡΡΠΈΡΠΎΠ²Π°Π½Π° Π²ΡΡΠΎΠΊΠ°Ρ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΠΠΠΊ-ΠΠ¦Π ΠΊΠ°ΠΊ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΠΎΠ³ΠΎ ΡΠ»ΡΠΎΡΠ΅ΡΡΠ΅Π½ΡΠ½ΠΎΠ³ΠΎ Π°Π³Π΅Π½ΡΠ° Π΄Π»Ρ ΠΎΠΏΡΡ
ΠΎΠ»Π΅ΡΠΏΠ΅ΡΠΈΡΠΈΡΠ½ΠΎΠΉ ΠΈΠ½ΡΡΠ°ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ Π²ΠΈΠ·ΡΠ°Π»ΠΈΠ·Π°ΡΠΈΠΈ ΠΏΡΠΈ ΡΠ΅Π·Π΅ΠΊΡΠΈΠΈ ΡΠ°ΠΊΠ° ΠΌΠΎΡΠ΅Π²ΠΎΠ³ΠΎ ΠΏΡΠ·ΡΡΡ ΠΈ Π±ΠΎΠ»ΡΡΠΎΠΉ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π» Π΄Π»Ρ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ Π΄Π°Π»ΡΠ½Π΅ΠΉΡΠΈΡ
ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ
ΠΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ Π°ΡΠΏΠ΅ΠΊΡΡ ΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π΅Π½ΠΈΠΉ ΠΏΡΠΎΠΊΡΠΈΠΌΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΎΡΠ΄Π΅Π»Π° ΠΏΠ»Π΅ΡΠ΅Π²ΠΎΠΉ ΠΊΠΎΡΡΠΈ Ρ ΡΠ°Π·Π½ΡΡ Π²ΠΎΠ·ΡΠ°ΡΡΠ½ΡΡ Π³ΡΡΠΏΠΏ
Introduction. Fracture of the proximal humerus is a common injury that accounts for up to 12 % of all bone fractures and up to 65 % of humeral fractures. 13 % to 16 % of fractures in this segment are multi-fragment with bone impression. This significantly complicates the task of internal fixation. This study aims to analyze the gender and age group distribution of patients with proximal humerus fractures, and morphological aspects of these injuries.Materials and methods. This paper presents a retrospective analysis of the epidemiological and morphological parameters of patients treated surgically for proximal humerus injuries at the Department of Traumatology and Orthopedics of the State Regional Clinical Hospital of the Republic of Bashkortostan β 1 in the city of Oktyabrsky in 2010β2016. The total of 191 patients were included in the study, 121 (63.35 %) females and 70 (36.65 %) males.Results and discussions. A signifi cant increase (more than three times) in the number of proximal humerus fractures was recorded in women in the 50β65 age group and in men in the 55β60 age group. The increase in the incidence of this type of injury does not exceed 22.4 % in comparison to the younger age groups. The increase in the number of injuries in question is undoubtedly due to changes in the bone metabolism in women. The analysis of character and morphology of fractures in women of older age groups indicates a greater prevalence of unstable injury of type 1.1.B and 1.1.C according to AO/ASIF classifi cation, which, again, is due to the demineralization of the segment determined by systemic metabolic abnormalities. The fi ndings indicate the need for perioperative monitoring of the bone metabolism parameters.Conclusion.The morphology and types of fractures depend on a patientβs age and bone quality. A signifi cant increase in this pathology in women of perimenopausal age refl ects changes in bone metabolism.ΠΠ²Π΅Π΄Π΅Π½ΠΈΠ΅. ΠΠ΅ΡΠ΅Π»ΠΎΠΌΡ ΠΏΡΠΎΠΊΡΠΈΠΌΠ°Π»ΡΠ½ΠΎΠΉ ΡΠ°ΡΡΠΈ ΠΏΠ»Π΅ΡΠ΅Π²ΠΎΠΉ ΠΊΠΎΡΡΠΈ β ΡΡΠΎ ΡΡΠ°Π²ΠΌΠ°, ΠΊΠΎΡΠΎΡΠ°Ρ ΡΠΎΡΡΠ°Π²Π»ΡΠ΅Ρ Π΄ΠΎ 12 % ΠΎΡ ΡΠΈΡΠ»Π° Π²ΡΠ΅Ρ
ΠΏΠ΅ΡΠ΅Π»ΠΎΠΌΠΎΠ² ΠΊΠΎΡΡΠ΅ΠΉ ΡΠΊΠ΅Π»Π΅ΡΠ° ΠΈ Π΄ΠΎ 65 % ΠΎΡ ΠΏΠ΅ΡΠ΅Π»ΠΎΠΌΠΎΠ² ΠΏΠ»Π΅ΡΠ΅Π²ΠΎΠΉ ΠΊΠΎΡΡΠΈ. ΠΡ 13 Π΄ΠΎ 16 % ΠΏΠ΅ΡΠ΅Π»ΠΎΠΌΠΎΠ² Π² Π΄Π°Π½Π½ΠΎΠΌ ΡΠ΅Π³ΠΌΠ΅Π½ΡΠ΅ ΠΈΠΌΠ΅ΡΡ ΠΌΠ½ΠΎΠ³ΠΎΠΎΡΠΊΠΎΠ»ΡΡΠ°ΡΡΠΉ Ρ
Π°ΡΠ°ΠΊΡΠ΅Ρ Ρ ΠΈΠΌΠΏΡΠ΅ΡΡΠΈΠ΅ΠΉ ΠΊΠΎΡΡΠ½ΠΎΠΉ ΡΠΊΠ°Π½ΠΈ, ΡΡΠΎ Π·Π½Π°ΡΠΈΡΠ΅Π»ΡΠ½ΠΎ ΡΡΠ»ΠΎΠΆΠ½ΡΠ΅Ρ Π·Π°Π΄Π°ΡΡ Π²Π½ΡΡΡΠ΅Π½Π½Π΅ΠΉ ΡΠΈΠΊΡΠ°ΡΠΈΠΈ. Π¦Π΅Π»Ρ Π΄Π°Π½Π½ΠΎΠ³ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ β ΠΏΡΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°ΡΡ Π³Π΅Π½Π΄Π΅ΡΠ½ΡΡ ΠΈ Π²ΠΎΠ·ΡΠ°ΡΡΠ½ΡΡ ΡΡΡΡΠΊΡΡΡΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ ΠΏΠ΅ΡΠ΅Π»ΠΎΠΌΠ°ΠΌΠΈ ΠΏΡΠΎΠΊΡΠΈΠΌΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΎΡΠ΄Π΅Π»Π° ΠΏΠ»Π΅ΡΠ΅Π²ΠΎΠΉ ΠΊΠΎΡΡΠΈ, Π° ΡΠ°ΠΊΠΆΠ΅ ΠΌΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ Π΄Π°Π½Π½ΡΡ
ΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π΅Π½ΠΈΠΉ.ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. ΠΡΠΎΠ²Π΅Π΄Π΅Π½ ΡΠ΅ΡΡΠΎΡΠΏΠ΅ΠΊΡΠΈΠ²Π½ΡΠΉ Π°Π½Π°Π»ΠΈΠ· ΡΠΏΠΈΠ΄Π΅ΠΌΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΈ ΠΌΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΏΠ°ΡΠ°ΠΌΠ΅ΡΡΠΎΠ² ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ², ΠΏΡΠΎΠΎΠΏΠ΅ΡΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
ΠΏΠΎ ΠΏΠΎΠ²ΠΎΠ΄Ρ ΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π΅Π½ΠΈΠΉ ΠΏΡΠΎΠΊΡΠΈΠΌΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΎΡΠ΄Π΅Π»Π° ΠΏΠ»Π΅ΡΠ΅Π²ΠΎΠΉ ΠΊΠΎΡΡΠΈ Π½Π° Π±Π°Π·Π΅ ΠΎΡΠ΄Π΅Π»Π΅Π½ΠΈΡ ΡΡΠ°Π²ΠΌΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΈ ΠΎΡΡΠΎΠΏΠ΅Π΄ΠΈΠΈ ΠΠΠ£Π Π Π ΠΠ β 1 Π³. ΠΠΊΡΡΠ±ΡΡΡΠΊΠΈΠΉ Π·Π° ΠΏΠ΅ΡΠΈΠΎΠ΄ Ρ Π½ΠΎΡΠ±ΡΡ 2010 ΠΏΠΎ Π½ΠΎΡΠ±ΡΡ 2016 Π³.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΈ ΠΎΠ±ΡΡΠΆΠ΄Π΅Π½ΠΈΠ΅. ΠΠ½Π°ΡΠΈΡΠ΅Π»ΡΠ½ΠΎΠ΅ ΡΠ²Π΅Π»ΠΈΡΠ΅Π½ΠΈΠ΅ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²Π° ΠΏΠ΅ΡΠ΅Π»ΠΎΠΌΠΎΠ² ΠΏΡΠΎΠΊΡΠΈΠΌΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΎΡΠ΄Π΅Π»Π° ΠΏΠ»Π΅ΡΠ΅Π²ΠΎΠΉ ΠΊΠΎΡΡΠΈ (Π±ΠΎΠ»Π΅Π΅ ΡΠ΅ΠΌ Π² 3 ΡΠ°Π·Π°) ΡΠ΅Π³ΠΈΡΡΡΠΈΡΡΠ΅ΡΡΡ Ρ ΠΆΠ΅Π½ΡΠΈΠ½ Π² Π²ΠΎΠ·ΡΠ°ΡΡΠ½ΠΎΠΉ Π³ΡΡΠΏΠΏΠ΅ 50β65 Π»Π΅Ρ, Ρ ΠΌΡΠΆΡΠΈΠ½ Π² Π²ΠΎΠ·ΡΠ°ΡΡΠ½ΠΎΠΉ ΠΊΠ°ΡΠ΅Π³ΠΎΡΠΈΠΈ 55β60 Π»Π΅Ρ. Π£Π²Π΅Π»ΠΈΡΠ΅Π½ΠΈΠ΅ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²Π° ΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π΅Π½ΠΈΠΉ Ρ ΠΆΠ΅Π½ΡΠΈΠ½, Π½Π΅ΡΠΎΠΌΠ½Π΅Π½Π½ΠΎ, ΠΎΠ±ΡΡΠ»ΠΎΠ²Π»Π΅Π½ΠΎ ΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΠΎΠΏΠ°ΡΠ·Π°Π»ΡΠ½ΡΠΌΠΈ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΡΠΌΠΈ ΠΊΠΎΡΡΠ½ΠΎΠ³ΠΎ ΠΌΠ΅ΡΠ°Π±ΠΎΠ»ΠΈΠ·ΠΌΠ°. ΠΠ½Π°Π»ΠΈΠ· Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠ° ΠΈ ΠΌΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠ΅ΠΉ ΠΏΠ΅ΡΠ΅Π»ΠΎΠΌΠΎΠ² Ρ ΠΆΠ΅Π½ΡΠΈΠ½ ΡΡΠ°ΡΡΠΈΡ
Π²ΠΎΠ·ΡΠ°ΡΡΠ½ΡΡ
Π³ΡΡΠΏΠΏ ΡΠ²ΠΈΠ΄Π΅ΡΠ΅Π»ΡΡΡΠ²ΡΠ΅Ρ ΠΎ Π±ΠΎΠ»ΡΡΠ΅ΠΉ ΡΠ°ΡΠΏΡΠΎΡΡΡΠ°Π½Π΅Π½Π½ΠΎΡΡΠΈ Π½Π΅ΡΡΠ°Π±ΠΈΠ»ΡΠ½ΡΡ
ΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π΅Π½ΠΈΠΉ ΡΠΈΠΏΠ° 1.1.Π ΠΈ 1.1.Π‘ ΠΏΠΎ ΠΊΠ»Π°ΡΡΠΈΡΠΈΠΊΠ°ΡΠΈΠΈ ΠΠ/ASIF, ΡΡΠΎ ΠΎΠΏΡΡΡ-ΡΠ°ΠΊΠΈ ΠΎΠ±ΡΡΠ»ΠΎΠ²Π»Π΅Π½ΠΎ Π΄Π΅ΠΌΠΈΠ½Π΅ΡΠ°Π»ΠΈΠ·Π°ΡΠΈΠ΅ΠΉ ΡΠ΅Π³ΠΌΠ΅Π½ΡΠ° Π½Π° ΡΠΎΠ½Π΅ ΡΠΎΠΏΡΡΡΡΠ²ΡΡΡΠΈΡ
ΠΎΠ±ΠΌΠ΅Π½Π½ΠΎ-ΠΌΠ΅ΡΠ°Π±ΠΎΠ»ΠΈΡΠ΅ΡΠΊΠΈΡ
Π½Π°ΡΡΡΠ΅Π½ΠΈΠΉ ΡΠΈΡΡΠ΅ΠΌΠ½ΠΎΠ³ΠΎ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠ°. ΠΡΡΠ²Π»Π΅Π½Π½ΡΠ΅ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ ΡΠ²ΠΈΠ΄Π΅ΡΠ΅Π»ΡΡΡΠ²ΡΡΡ ΠΎ Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠΎΡΡΠΈ ΠΏΠ΅ΡΠΈΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΠΌΠΎΠ½ΠΈΡΠΎΡΠΈΠ½Π³Π° ΠΏΠ°ΡΠ°ΠΌΠ΅ΡΡΠΎΠ² ΠΊΠΎΡΡΠ½ΠΎΠ³ΠΎ ΠΌΠ΅ΡΠ°Π±ΠΎΠ»ΠΈΠ·ΠΌΠ°.ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. ΠΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΡ ΠΈ ΡΠΈΠΏΡ ΠΏΠ΅ΡΠ΅Π»ΠΎΠΌΠΎΠ² Π·Π°Π²ΠΈΡΡΡ ΠΎΡ Π²ΠΎΠ·ΡΠ°ΡΡΠ° ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ° ΠΈ ΠΊΠ°ΡΠ΅ΡΡΠ²Π° ΠΊΠΎΡΡΠΈ. ΠΠ½Π°ΡΠΈΡΠ΅Π»ΡΠ½ΡΠΉ ΡΠΎΡΡ Π΄Π°Π½Π½ΠΎΠΉ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΠΈ Ρ ΠΆΠ΅Π½ΡΠΈΠ½ ΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΠΎΠΏΠ°ΡΠ·Π°Π»ΡΠ½ΠΎΠ³ΠΎ Π²ΠΎΠ·ΡΠ°ΡΡΠ° Π³ΠΎΠ²ΠΎΡΠΈΡ ΠΎΠ± ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΡΡ
ΠΌΠ΅ΡΠ°Π±ΠΎΠ»ΠΈΠ·ΠΌΠ° Π² ΠΊΠΎΡΡΡΡ
, Π²ΡΠ»Π΅Π΄ΡΡΠ²ΠΈΠ΅ ΡΠ΅Π³ΠΎ Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌ ΠΌΠΎΠ½ΠΈΡΠΎΡΠΈΠ½Π³ ΠΊΠΎΡΡΠ½ΠΎΠ³ΠΎ ΠΌΠ΅ΡΠ°Π±ΠΎΠ»ΠΈΠ·ΠΌΠ° Π² ΠΏΠ΅ΡΠΈΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΎΠ½Π½ΡΠΉ ΠΏΠ΅ΡΠΈΠΎΠ΄
Π Π°Π½Π½ΠΈΠ΅ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΡ ΠΊΠ»ΠΈΠ½ΠΈΠΊΠΎ-Π»Π°Π±ΠΎΡΠ°ΡΠΎΡΠ½ΡΡ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ Ρ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ², ΡΠΌΠ΅ΡΡΠΈΡ ΠΎΡ COVID-19
261,435,768 COVID-19 infections were detected worldwide, of them 5,207,634 deaths were registered. Identifying markers of the patient severity early in the course of the disease can facilitate the assessment of the risk of adverse outcome.The objective: To compare values of laboratory parameters and their changes during treatment of patients with a complicated course of COVID-19 infection.Subjects and Methods. 56 patients were included in the study, all of them were hospitalized to COVID Hospital of the Clinic of Bashkir State Medical University, Russian Ministry of Health, from September 30, 2021 to November 15, 2021, and their complicated course of the disease necessitated transfer to the intensive care unit (ICU). The laboratory evaluation included the following: a general blood and urine counts, blood chemistry including urea and creatinine, liver transaminases, and blood coagulogram (prothrombin time (PTT), prothrombin index (PTI), thrombin time, fibrinogen, and blood clotting time).Results. In the group of patients with a fatal outcome on the day of transfer to ICU, lymphocytopenia, eosinopenia, elevated values of creatinine, total bilirubin, transaminases, C-reactive protein, D-dimer, and ferritin were noted. Also on this day, microscopic hematuria, proteinuria and cylindruria were detected in the urine tests of most patients in this group during treatment.Conclusion. Critical deviations in the results of hematological and biochemical tests were revealed. Particular attention should be paid to such parameters as the level of erythrocytes, lymphocytes, eosinophils, glucose, urea, creatinine, total bilirubin, aspartate aminotransferase, alanine aminotransferase, creatine kinase, C-reactive protein, D-dimer, and ferritin.ΠΠΎ Π΄Π°Π½Π½ΡΠΌ Π½Π° 01.12.2021 Π³., Π²ΠΎ Π²ΡΠ΅ΠΌ ΠΌΠΈΡΠ΅ Π²ΡΡΠ²Π»Π΅Π½ΠΎ 261 435 768 Π·Π°Π±ΠΎΠ»Π΅Π²ΡΠΈΡ
COVID-19, ΠΈΠ· ΠΊΠΎΡΠΎΡΡΡ
5 207 634 ΡΠΌΠ΅ΡΠ»ΠΈ. ΠΡΡΠ²Π»Π΅Π½ΠΈΠ΅ ΠΌΠ°ΡΠΊΠ΅ΡΠΎΠ² ΡΡΠΆΠ΅ΡΡΠΈ ΡΠΎΡΡΠΎΡΠ½ΠΈΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Π½Π° ΡΠ°Π½Π½ΠΈΡ
ΡΡΠΎΠΊΠ°Ρ
Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ ΠΌΠΎΠΆΠ΅Ρ ΠΎΠ±Π»Π΅Π³ΡΠΈΡΡ ΠΎΡΠ΅Π½ΠΊΡ ΡΠΈΡΠΊΠ° Π½Π΅Π±Π»Π°Π³ΠΎΠΏΡΠΈΡΡΠ½ΠΎΠ³ΠΎ ΠΈΡΡ
ΠΎΠ΄Π°.Π¦Π΅Π»Ρ: ΡΡΠ°Π²Π½ΠΈΡΡ Π·Π½Π°ΡΠ΅Π½ΠΈΡ Π»Π°Π±ΠΎΡΠ°ΡΠΎΡΠ½ΡΡ
ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ ΠΈ ΠΈΡ
Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΡ Π² ΠΏΡΠΎΡΠ΅ΡΡΠ΅ Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½Π½ΡΠΌ ΡΠ΅ΡΠ΅Π½ΠΈΠ΅ΠΌ COVID-19.ΠΠ°ΡΠ΅ΡΠΈΠ°Π» ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ: Π² ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΈ ΠΏΡΠΈΠ½ΡΠ»ΠΈ ΡΡΠ°ΡΡΠΈΠ΅ 56 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ², Π³ΠΎΡΠΏΠΈΡΠ°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
Π² ΠΊΠΎΠ²ΠΈΠ΄-Π³ΠΎΡΠΏΠΈΡΠ°Π»Ρ ΠΊΠ»ΠΈΠ½ΠΈΠΊΠΈ Π€ΠΠΠΠ£ ΠΠ Β«ΠΠΠΠ£Β» ΠΠΈΠ½Π·Π΄ΡΠ°Π²Π° Π ΠΎΡΡΠΈΠΈ Ρ 30.09.2021 Π³. ΠΏΠΎ 15.11.2021 Π³., ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½Π½ΠΎΠ΅ ΡΠ΅ΡΠ΅Π½ΠΈΠ΅ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ ΠΊΠΎΡΠΎΡΡΡ
Π²ΡΠ·Π²Π°Π»ΠΎ Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠΎΡΡΡ ΠΏΠ΅ΡΠ΅Π²ΠΎΠ΄Π° Π² ΠΎΡΠ΄Π΅Π»Π΅Π½ΠΈΠ΅ ΡΠ΅Π°Π½ΠΈΠΌΠ°ΡΠΈΠΈ ΠΈ ΠΈΠ½ΡΠ΅Π½ΡΠΈΠ²Π½ΠΎΠΉ ΡΠ΅ΡΠ°ΠΏΠΈΠΈ (ΠΠ ΠΠ’). ΠΠ±ΡΠ΅ΠΌ Π»Π°Π±ΠΎΡΠ°ΡΠΎΡΠ½ΠΎΠ³ΠΎ ΠΎΠ±ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ: ΠΎΠ±ΡΠΈΠΉ Π°Π½Π°Π»ΠΈΠ· ΠΊΡΠΎΠ²ΠΈ ΠΈ ΠΌΠΎΡΠΈ, Π±ΠΈΠΎΡ
ΠΈΠΌΠΈΡΠ΅ΡΠΊΠΈΠΉ Π°Π½Π°Π»ΠΈΠ· ΠΊΡΠΎΠ²ΠΈ Ρ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ΠΌ ΡΡΠΎΠ²Π½Π΅ΠΉ ΠΌΠΎΡΠ΅Π²ΠΈΠ½Ρ ΠΈ ΠΊΡΠ΅Π°ΡΠΈΠ½ΠΈΠ½Π°, ΠΏΠ΅ΡΠ΅Π½ΠΎΡΠ½ΡΡ
ΡΡΠ°Π½ΡΠ°ΠΌΠΈΠ½Π°Π·, ΠΊΠΎΠ°Π³ΡΠ»ΠΎΠ³ΡΠ°ΠΌΠΌΠ° ΠΊΡΠΎΠ²ΠΈ (ΠΏΡΠΎΡΡΠΎΠΌΠ±ΠΈΠ½ΠΎΠ²ΠΎΠ΅ Π²ΡΠ΅ΠΌΡ, ΠΏΡΠΎΡΡΠΎΠΌΠ±ΠΈΠ½ΠΎΠ²ΡΠΉ ΠΈΠ½Π΄Π΅ΠΊΡ, ΡΡΠΎΠΌΠ±ΠΈΠ½ΠΎΠ²ΠΎΠ΅ Π²ΡΠ΅ΠΌΡ, ΡΠΈΠ±ΡΠΈΠ½ΠΎΠ³Π΅Π½, Π²ΡΠ΅ΠΌΡ ΡΠ²Π΅ΡΡΡΠ²Π°Π½ΠΈΡ ΠΊΡΠΎΠ²ΠΈ).Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. Π Π³ΡΡΠΏΠΏΠ΅ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ Π»Π΅ΡΠ°Π»ΡΠ½ΡΠΌ ΠΈΡΡ
ΠΎΠ΄ΠΎΠΌ Π² Π΄Π΅Π½Ρ ΠΏΠ΅ΡΠ΅Π²ΠΎΠ΄Π° Π² ΠΠ ΠΠ’ ΠΎΡΠΌΠ΅ΡΠ΅Π½Ρ Π»ΠΈΠΌΡΠΎΡΠΈΡΠΎΠΏΠ΅Π½ΠΈΡ, ΡΠΎΠ·ΠΈΠ½ΠΎΠΏΠ΅Π½ΠΈΡ, ΠΏΠΎΠ²ΡΡΠ΅Π½Π½ΡΠ΅ Π·Π½Π°ΡΠ΅Π½ΠΈΡ ΠΊΡΠ΅Π°ΡΠΈΠ½ΠΈΠ½Π°, ΠΎΠ±ΡΠ΅Π³ΠΎ Π±ΠΈΠ»ΠΈΡΡΠ±ΠΈΠ½Π°, ΡΡΠ°Π½ΡΠ°ΠΌΠΈΠ½Π°Π·, Π‘-ΡΠ΅Π°ΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ Π±Π΅Π»ΠΊΠ°, D-Π΄ΠΈΠΌΠ΅ΡΠ° ΠΈ ΡΠ΅ΡΡΠΈΡΠΈΠ½Π°. Π’Π°ΠΊΠΆΠ΅ Π² ΡΡΠΎΡ Π΄Π΅Π½Ρ Π² Π°Π½Π°Π»ΠΈΠ·Π°Ρ
ΠΌΠΎΡΠΈ Ρ Π±ΠΎΠ»ΡΡΠΈΠ½ΡΡΠ²Π° ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Π΄Π°Π½Π½ΠΎΠΉ Π³ΡΡΠΏΠΏΡ Π² Ρ
ΠΎΠ΄Π΅ Π»Π΅ΡΠ΅Π½ΠΈΡ Π±ΡΠ»ΠΈ ΠΎΠ±Π½Π°ΡΡΠΆΠ΅Π½Ρ ΠΌΠΈΠΊΡΠΎΡΠΊΠΎΠΏΠΈΡΠ΅ΡΠΊΠ°Ρ Π³Π΅ΠΌΠ°ΡΡΡΠΈΡ, ΠΏΡΠΎΡΠ΅ΠΈΠ½ΡΡΠΈΡ ΠΈ ΡΠΈΠ»ΠΈΠ½Π΄ΡΡΡΠΈΡ.ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. ΠΡΡΠ²Π»Π΅Π½Ρ ΠΊΡΠΈΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΎΡΠΊΠ»ΠΎΠ½Π΅Π½ΠΈΡ Π² ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ°Ρ
Π³Π΅ΠΌΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
, Π±ΠΈΠΎΡ
ΠΈΠΌΠΈΡΠ΅ΡΠΊΠΈΡ
Π°Π½Π°Π»ΠΈΠ·ΠΎΠ². ΠΡΠΎΠ±ΠΎΠ΅ Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅ Π΄ΠΎΠ»ΠΆΠ½ΠΎ Π±ΡΡΡ ΡΠ΄Π΅Π»Π΅Π½ΠΎ ΡΠ°ΠΊΠΈΠΌ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΡΠΌ, ΠΊΠ°ΠΊ ΡΡΠΎΠ²Π΅Π½Ρ ΡΡΠΈΡΡΠΎΡΠΈΡΠΎΠ², Π»ΠΈΠΌΡΠΎΡΠΈΡΠΎΠ², ΡΠΎΠ·ΠΈΠ½ΠΎΡΠΈΠ»ΠΎΠ², Π³Π»ΡΠΊΠΎΠ·Ρ, ΠΌΠΎΡΠ΅Π²ΠΈΠ½Ρ, ΠΊΡΠ΅Π°ΡΠΈΠ½ΠΈΠ½Π°, ΠΎΠ±ΡΠ΅Π³ΠΎ Π±ΠΈΠ»ΠΈΡΡΠ±ΠΈΠ½Π°, Π°ΡΠΏΠ°ΡΡΠ°ΡΠ°ΠΌΠΈΠ½ΠΎΡΡΠ°Π½ΡΡΠ΅ΡΠ°Π·Ρ, Π°Π»Π°Π½ΠΈΠ½Π°ΠΌΠΈΠ½ΠΎΡΡΠ°Π½ΡΡΠ΅ΡΠ°Π·Ρ, ΠΊΡΠ΅Π°ΡΠΈΠ½ΠΊΠΈΠ½Π°Π·Ρ, Π‘-ΡΠ΅Π°ΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ Π±Π΅Π»ΠΊΠ°, D-Π΄ΠΈΠΌΠ΅ΡΠ°, ΡΠ΅ΡΡΠΈΡΠΈΠ½Π°
Morphometric variability of Xanthonema exile (Klebs) Silva (Xanthophyta) from Bashkir Pre-Ural Region (Russia)
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