香港的選擇性墮胎: 合法與否?

There is legal uncertainty as to whether selective foeticide is authorised under section 47A of the Offences Against the Person Ordinance (1967). Medical and legal issues surrounding a case of selective foeticide in a triplet pregnancy are reported.published_or_final_versio

Permutation-based DCSK and multiple-access DCSK systems

Author name used in this publication: Francis C. M. LauAuthor name used in this publication: Kai Y. CheongAuthor name used in this publication: Chi K. Tse2002-2003 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

Human enterovirus 71 and hand, foot and mouth disease

Hand, foot and mouth disease (HFMD) is generally a benign febrile exanthematous childhood disease caused by human enteroviruses. The route of transmission is postulated to be faeco-oral in developing areas but attributed more to respiratory droplet in developed areas. Transmission is facilitated by the prolonged environmental survival of these viruses and their greater resistance to biocides. Serious outbreaks with neurological and cardiopulmonary complications caused by human enterovirus 71 (HEV-71) seem to be commoner in the Asian Pacific region than elsewhere in the world. This geographical predilection is unexplained but could be related to the frequency of intra- and inter-typic genetic recombinations of the virus, the host populations' genetic predisposition, environmental hygiene, and standard of healthcare. Vaccine development could be hampered by the general mildness of the illness and rapid genetic evolution of the virus. Antivirals are not readily available; the role of intravenous immunoglobulin in the treatment of serious complications should be investigated. Monitoring of this disease and its epidemiology in the densely populated Asia Pacific epicentre is important for the detection of emerging epidemics due to enteroviruses. Copyright © 2010 Cambridge University Press.published_or_final_versio

Induction chemotherapy for squamous cell carcinomas of the oral cavity: A cumulative meta-analysis

Induction chemotherapy (ICT) is a controversial treatment for head and neck squamous cell carcinomas (HNSCC). Despite numerous randomized controlled trials (RCTs), a majority do not have enough statistical power alone to conclude ICT’s treatment value among oral squamous carcinoma patients (OSCC) since many addressed HNSCC as one entity instead of by specific subtypes. By performing a systematic review and cumulative meta-analysis, we aim to determine the benefits of ICT in OSCC therapy. A literature search identified for RCTs comparing OSCC patients who received ICT against those without. Log-hazard ratio, and relative risk were used for comparison. Heterogeneity was determined using the I2 statistic package. The primary endpoint was overall survival (OS), followed by disease-free survival (DFS), locoregional recurrence (LRR) and distant metastasis (DM) as secondary endpoints. RESULTS: 27 randomized trials were included for analysis (n = 2872 patients). The shortest median follow-up was 15 months whereas the longest was 11.5 years. ICT does not improve OS (HR = 0.947, 95% CI 0.85–1.05, p = 0.318), DFS (RR = 1.05, 95% CI 0.92–1.21, p = 0.462) and DM (RR = 0.626, CI 95% 0.361–1.086, p = 0.096) compared to locoregional treatment alone. However, there was a significant improvement to LRR (RR = 0.778, 95% CI 0.622–0.972, p = 0.027). There is no evidence ICT improves survival outcomes for OSCC patients. However, ICT reduces locoregional recurrence of OSCC, which may need further verification.preprin

Concomitant plasmacytoma and B cell lymphoma with discordant light chain expression but clonal identity

Letter to the editorpublished_or_final_versionSpringer Open Choice, 25 May 201

Viral loads in clinical specimens and SARS manifestations.

1. A high viral load in nasopharyngeal aspirate (with or without a high viral load in serum) is a useful prognostic indicator of respiratory failure or mortality. The presence of viral RNA in multiple body sites is also indicative of poor prognosis. 2. Early treatment with an effective antiviral agent before day 10 may decrease the peak viral load, and thus ameliorate the clinical symptoms and mortality, and reduce viral shedding and the risk of transmissionpublished_or_final_versio

Human enterovirus 71 epidemics: what's next?

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Invasive Acremonium falciforme infection in a patient with severe combined immunodeficiency [7]

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Acupuncture transmitted infections.

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Return-map-based approaches for noncoherent detection in chaotic digital communications

Author name used in this publication: C. K. TseAuthor name used in this publication: F. C. M. LauAuthor name used in this publication: K. Y. CheongAuthor name used in this publication: S. F. Hau2002-2003 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe