ASSESSMENT OF PHARMACIST MEDIATED EDUCATION ON HEALTH RELATED QUALITY OF LIFE IN TYPE 2 DIABETES MELLITUS PATIENTS IN RURAL SOUTH INDIAN POPULATION

Objective: To assess the influence of pharmacist mediated education on health-related quality of life in rural patients with type 2 diabetes mellitus. Methodology: This is a prospective, randomized interventional study approved by the institutional ethics committee. Eligible type 2 diabetic patients with written informed consent were enrolled and randomized into control and test group. Diabetic health profile-18 (DHP-18) questionnaire was administered to all patients at baseline and three subsequent follow-ups. Patients in the test group received structured education at every follow up whereas the control group patients received education only at the final follow up. SPSS software was used to evaluate the data.Results: Among the 72 patients enrolled, 35 were randomized into control group and 37 into test group. Majority of the study patients were males (65.2%) with an age range of 30 to 72 years and were from agriculture profession (34.72%) with school-level education (59.7%). The mean BMI of the study patients was 25.01. At baseline, the mean glycosylated haemoglobin (HbA1C) values of patients were 6.48±1.39% in the control group and 6.23±1.16% in the test group. During the last follow-up, a significant (p<0.05) improvement was observed in the DHP-18 scores in test group patients compared to control group patients which were supported by statistically significant (p<0.05) improvement in capillary blood glucose (CBG) values.Conclusion: Pharmacist mediated structured education has shown a positive impact on health-related quality of life in test group patients towards their disease management.Keywords: Diabetes, Therapeutic Outcome, Health-Related Quality of Life

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Not AvailableMango is one of the most important fruits of tropical ecological region of the world, well known for its nutritive value, aroma and taste. Its world production is >45MT worth >200 billion US dollars. Genomic resources are required for improvement in productivity and management of mango germplasm. There is no web-based genomic resources available for mango. Hence rapid and cost-effective high throughput putative marker discovery is required to develop such resources. RAD-based marker discovery can cater this urgent need till whole genome sequence of mango becomes available. Using a panel of 84 mango varieties, a total of 28.6 Gb data was generated by ddRAD-Seq approach on Illumina HiSeq 2000 platform. A total of 1.25 million SNPs were discovered. Phylogenetic tree using 749 common SNPs across these varieties revealed three major lineages which was compared with geographical locations. A web genomic resources MiSNPDb, available at http://webtom.cabgrid.res.in/mangosnps/ is based on 3-tier architecture, developed using PHP, MySQL and Javascript. This web genomic resources can be of immense use in the development of high density linkage map, QTL discovery, varietal differentiation, traceability, genome finishing and SNP chip development for future GWAS in genomic selection program. We report here world’s first web-based genomic resources for genetic improvement and germplasm management of mango.Not Availabl