11 research outputs found
Le desflurane, comparé à l’isoflurane, au sêvoflurane ou au propofol, réduit davantage la vitesse de perfusion thérapeutique utile (PTU) du cisatracurium
Zur Historizität soziologischer Gegenstände und ihren Implikationen für eine wissenssoziologische Konzeptualisierung von Soziologiegeschichte
High K+-induced contraction requires depolarization-induced Ca2+ release from internal stores in rat gut smooth muscle
Folk Theories of Happiness: A Cross-Cultural Comparison of Conceptions of Happiness in Germany and South Africa
Happiness, Folk theory, Germany, South africa,
Leaf chlorophyll estimates of temperate deciduous shrubs during autumn senescence using a SPAD-502 meter and calibration with extracted chlorophyll
High-throughput fluorescence assays for ion channels and GPCRs
Ca2+, Na+ and K+- permeable ion channels as well as GPCRs linked to Ca2+ release are important drug targets. Accordingly, high-throughput fluorescence plate reader assays have contributed substantially to drug discovery efforts and pharmacological characterization of these receptors and ion channels. This chapter describes some of the basic properties of the fluorescent dyes facilitating these assay approaches as well as general methods for establishment and optimisation of fluorescence assays for ion channels and Gq-coupled GPCRs