320 research outputs found

    High-Speed AFM Observation of Antibody IGG Characteristic of Swinging Arms

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    Suzaku and Optical Spectroscopic Observations of SS 433 in the 2006 April Multiwavelength Campaign

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    We report results of the 2006 April multi-wavelengths campaign of SS 433, focusing on X-ray data observed with Suzaku at two orbital phases (in- and out-of- eclipse) and simultaneous optical spectroscopic observations. By analyzing the Fe25 K_alpha lines originating from the jets, we detect rapid variability of the Doppler shifts, dz/dt ~ 0.019/0.33 day^-1, which is larger than those expected from the precession and/or nodding motion. This phenomenon probably corresponding to "jitter" motions observed for the first time in X-rays, for which significant variability both in the jet angle and intrinsic speed is required. From the time lag of optical Doppler curves from those of X-rays, we estimate the distance of the optical jets from the base to be ~(3-4) \times 10^14 cm. Based on the radiatively cooling jet model, we determine the innermost temperature of the jets to be T_0 = 13 +/- 2 keV and 16 +/- 3 keV (the average of the blue and red jets) for the out-of-eclipse and in-eclipse phase, respectively, from the line intensity ratio of Fe25 K_alpha and Fe26 K_alpha. While the broad band continuum spectra over the 5--40 keV band in eclipse is consistent with a multi-temperature bremsstrahlung emission expected from the jets, and its reflection component from cold matter, the out-of-eclipse spectrum is harder than the jet emission with the base temperature determined above, implying the presence of an additional hard component.Comment: 12 pages, 15 figures, accepted for publication in PAS

    Large-cell neuroendocrine carcinoma of lung with epidermal growth factor receptor (EGFR) gene mutation and co-expression of adenocarcinoma markers: a case report and review of the literature

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    PURPOSE: A high rate of response to treatment with epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) has been observed in certain patients (women, of East Asian ethnicity, with non-smoking history and adenocarcinoma histology) with mutations in exons 18 to 21 of the tyrosine kinase domain of EGFR. Some cases of high-grade neuroendocrine carcinoma of the lung harboring mutations have been sporadically reported. METHODS: We describe the case of a 78-year-old woman with large-cell neuroendocrine carcinoma of the lung, with mutation in exon 21 L858R and co-expression of adenocarcinoma markers. RESULTS: A mass (3.0 cm in diameter) was identified in the inferior lobe of the left lung, accompanied by metastases into ipsilateral mediastinal lymph nodes and elevations of serum pro-gastrin-releasing peptide and carcinoembryonic antigen. Initial transbronchial brushing cytology suggested high-grade neuroendocrine carcinoma favoring small-cell carcinoma in poorly smeared and degenerated preparations, and revealed exon 21 L858R mutation. Re-enlargement of the cancer and bone metastases was observed after chemotherapy, and further testing suggested large-cell neuroendocrine carcinoma with immunoreactivity to markers of primary lung adenocarcinoma and L858R mutation. High-grade neuroendocrine carcinoma with mutations in the tyrosine kinase domain of EGFR may be associated with adenocarcinoma, as reviewed from the literature and may also apply to our case. CONCLUSIONS: EGFR-TKI could provide better quality of life and survival in patients with advanced or relapsed high-grade neuroendocrine carcinoma with EGFR gene mutations. Further studies in this respect are warranted

    The State of Studies of Japanese Constitution in the U. S. and Europe <Research Note>

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    本文に記したように本稿は,2013年度~2015年度にかけて取得した,科研費・基盤研究(C)「欧米諸国における日本憲法研究の状況をめぐる憲法学的検証」(研究課題番号:25380038)に基づく研究成果である(なお,本研究の一部において,平成27年度慶磨義塾学事振興資金に基づく調査研究も反映されている)

    Electronic properties of alkali-metal loaded zeolites -- a "supercrystal" Mott insulator

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    First-principles band calculations are performed for the first time for an open-structured zeolite (LTA) with guest atoms (potassium) introduced in their cages. A surprisingly simple band structure emerges, which indicates that this system may be regarded as a "supercrystal", where each cluster of guest atoms with diameter \sim10\AA acts as a "superatom" with well-defined ss- and pp-like orbitals, which in turn form the bands around the Fermi energy. The calculated Coulomb and exchange energies for these states turn out to be in the strongly-correlated regime. With the dynamical mean-field theory we show the system should be on the Mott-insulator side, and, on a magnetic phase diagram for degenerate-orbital systems, around the ferromagnetic regime, in accord with experimental results. We envisage this class of systems can provide a new avenue for materials design.Comment: 4 pages, 4 figure

    Evidence for Spin–Orbit Alignment in the TRAPPIST-1 System

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    In an effort to measure the Rossiter–McLaughlin effect for the TRAPPIST-1 system, we performed high-resolution spectroscopy during transits of planets e, f, and b. The spectra were obtained with the InfraRed Doppler spectrograph on the Subaru 8.2 m telescope, and were supplemented with simultaneous photometry obtained with a 1 m telescope of the Las Cumbres Observatory Global Telescope. By analyzing the anomalous radial velocities, we found the projected stellar obliquity to be λ = 1 ± 28° under the assumption that the three planets have coplanar orbits, although we caution that the radial-velocity data show correlated noise of unknown origin. We also sought evidence for the expected deformations of the stellar absorption lines, and thereby detected the "Doppler shadow" of planet b with a false-alarm probability of 1.7%. The joint analysis of the observed residual cross-correlation map including the three transits gave λ = 19_(-15)^(+13)°. These results indicate that the the TRAPPIST-1 star is not strongly misaligned with the common orbital plane of the planets, although further observations are encouraged to verify this conclusion

    Planet(esimal)s Around Stars with TESS (PAST) III: A Search for Triplet He I in the Atmospheres of Two 200 Myr-old Planets

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    We report a search for excess absorption in the 1083.2 nm line of ortho (triplet) helium during transits of TOI-1807b and TOI-2076b, 1.25 and 2.5REarth_{\rm Earth} planets on 0.55- and 10.4-day orbits around nearby \sim200~Myr-old K dwarf stars. We limit the equivalent width of any transit-associated absorption to <<4 and <<8 mA, respectively. We limit the escape of solar-composition atmospheres from TOI-1807b and TOI-2076b to \lesssim1 and \lesssim0.1MEarth_{\rm Earth} Gyr1^{-1}, respectively, depending on wind temperature. The absence of a H/He signature for TOI-1807b is consistent with a measurement of mass indicating a rocky body and the prediction by a hydrodynamic model that any H-dominated atmosphere would be unstable and already have been lost. Differential spectra obtained during the transit of TOI-2076b contain a He I-like feature, but this closely resembles the stellar line and extends beyond the transit interval. Until additional transits are observed, we suspect this to be the result of variation in the stellar He I line produced by rotation of active regions and/or flaring on the young, active host star. Non-detection of escape could mean that TOI-2076b is more massive than expected, the star is less EUV-luminous, the models overestimate escape, or the planet has a H/He-poor atmosphere that is primarily molecules such as H2_2O. Photochemical models of planetary winds predict a semi-major axis at which triplet He I observations are most sensitive to mass loss: TOI-2076b orbits near this optimum. Future surveys could use a distance criterion to increase the yield of detections.Comment: Accepted to MNRA

    X-ray study of ferroic octupole order producing anomalous Hall effect

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    放射光でついに見えた磁気オクタポール --熱を電気に変える新たな担い手--. 京都大学プレスリリース. 2021-09-27.Recently found anomalous Hall, Nernst, magnetooptical Kerr, and spin Hall effects in the antiferromagnets Mn₃X (X = Sn, Ge) are attracting much attention for spintronics and energy harvesting. Since these materials are antiferromagnets, the origin of these functionalities is expected to be different from that of conventional ferromagnets. Here, we report the observation of ferroic order of magnetic octupole in Mn₃Sn by X-ray magnetic circular dichroism, which is only predicted theoretically so far. The observed signals are clearly decoupled with the behaviors of uniform magnetization, indicating that the present X-ray magnetic circular dichroism is not arising from the conventional magnetization. We have found that the appearance of this anomalous signal coincides with the time reversal symmetry broken cluster magnetic octupole order. Our study demonstrates that the exotic material functionalities are closely related to the multipole order, which can produce unconventional cross correlation functionalities
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