S-allylmercaptocysteine reduces carbon tetrachloride-induced hepatic oxidative stress and necroinflammation via nuclear factor kappa B-dependent pathways in mice

Purpose To study the protective effects and underlying molecular mechanisms of SAMC on carbon tetrachloride (CCl4)-induced acute hepatotoxicity in the mouse model. Methods Mice were intraperitoneally injected with CCl4 (50 μl/kg; single dose) to induce acute hepatotoxicity with or without a 2-h pre-treatment of SAMC intraperitoneal injection (200 mg/kg; single dose). After 8 h, the blood serum and liver samples of mice were collected and subjected to measurements of histological and molecular parameters of hepatotoxicity. Results SAMC reduced CCl4-triggered cellular necrosis and inflammation in the liver under histological analysis. Since co-treatment of SAMC and CCl4 enhanced the expressions of antioxidant enzymes, reduced the nitric oxide (NO)-dependent oxidative stress, and inhibited lipid peroxidation induced by CCl4. SAMC played an essential antioxidative role during CCl4-induced hepatotoxicity. Administration of SAMC also ameliorated hepatic inflammation induced by CCl4 via inhibiting the activity of NF-κB subunits p50 and p65, thus reducing the expressions of pro-inflammatory cytokines, mediators, and chemokines, as well as promoting pro-regenerative factors at both transcriptional and translational levels. Conclusions Our results indicate that SAMC mitigates cellular damage, oxidative stress, and inflammation in CCl4-induced acute hepatotoxicity mouse model through regulation of NF-κB. Garlic or garlic derivatives may therefore be a potential food supplement in the prevention of liver damage

Texturized geriatric footwear design for balance-enhancing and pressure management

RAE2020Other Versionnul

Validation of a 3D foot scanning system for evaluation of forefoot shape with elevated heels

2016-2017 > Academic research: refereed > Publication in refereed journal201804_a bcmaAccepted ManuscriptPublishe

Impact of co-creation footwear workshops on older women in elderly centers in Hong Kong

202101 bcrcVersion of RecordPublishe

Novel weft-knitted spacer structure with silicone tube and foam inlays for cushioning insoles

A novel spacer fabric with a weft-knitted structure of silicone tube and foam inlays is proposed for use in insoles to alleviate in-shoe pressure, reduce moisture and enhance thermal comfort. The material variables, including the diameter of the spacer yarn, type of inlaid material and net wrap and spacer pattern have been systematically investigated. Their force reduction and thermal characteristics in terms of air and water vapour permeabilities, thermal conductivity and impact force reduction are determined and compared to those of traditional insole materials. The results show that the inlays can effectively enhance the impact force reduction of the 3D spacer fabrics. In comparison to traditional insole materials, the proposed spacer fabric with an inlaid structure can enhance air and moisture permeabilities and heat dissipation to provide greater wear comfort for prolonged use. The air permeability, thermal conductivity and impact force reduction of the inlaid spacer structure can be modified with changes to the diameter of the spacer yarn, type of inlay and net material used and spacer pattern, whilst its water vapour permeability can also be varied by using different types of inlays. Spacer fabric with a higher number of spacer yarn courses and spacer yarn with a large diameter not only exhibits good impact force reduction with uniform thickness, but also offers good thermal conductivity. The findings of this study will contribute toward an insole design with the use of alternative insole materials for optimal foot protection

Development of laid-in knitted fabric for buoyant swimwear

As the use of buoyant swimwear by children in residential swimming becomes more common, the investigation of the effects of buoyant textiles is crucial for the optimisation of functional buoyant clothing design. This study investigated buoyant knitted fabrics developed using an inlaid knitting technique for buoyant swimwear application. The impact of the inner diameter, outer diameter, and the linear density of the inlaid tube on the buoyant ability of the buoyant fabrics was analyzed using multiple linear regression. The result demonstrated that the fabric’s net buoyant force was significantly affected by all three parameters, with inner diameter having the greatest effect, followed by the outer diameter and linear density of the inlaid tube. The increase in the net buoyant force of the fabric can be predicted by the increase in the inner diameter of its inlaid tube and linear density and decrease in the outer diameter. The divergence of the results for specimens inlaid with Silicon tube and from the result predicted by multiple linear regression indicates that the net buoyant force is also affected by the linear density and the wall thickness of the inlaid tube. The new knowledge of this study can contribute to the production of buoyant layers inside the buoyant swimwear in replace of air chambers to improve the limitation of non-distributed buoyancy, accidental punctuation and bulkiness in conventional buoyant swimwear

Influence of inlaid material, yarn and knitted structure on the net buoyant force and mechanical properties of inlaid knitted fabric for buoyant swimwear

Buoyant swimwear is becoming more common in recreational swimming use, so the performance of buoyant fabric is important when designing functional swimwear. In this study, potential buoyant inlaid knitted fabrics for buoyant swimwear are investigated. Three types of knitted structures, half milano, full milano and 1 × 1 rib, are selected and various kinds of tubes and foam rods in different diameters are prepared for inlaying during the knitting process by using a 7 G hand-knitting machine. The mean differences among the levels of three independent variables, (1) inlaid material, (2) yarn and (3) knitted structure, on three dependent variables (net buoyant force, compression and tensile properties) are analyzed by using a multivariate analysis of variance. The result shows that the net buoyant force and mechanical properties of the fabric are significantly different due to the inlaid material and knitted structure, but not the yarn. The net buoyant force increases with fabric thickness and the outer diameter of the inlaid material. The inlaid fabrics are less compressible than the control fabric and show better recoverability with an increase in the diameter of the inlaid material. For the tensile properties, the inlaid material reinforces the fabric in both the wale and course directions, in which the stiffness in the course direction is significantly increased. The inlaid fabric is stronger and resistant to breakage in the course direction when the diameter of the inlaid material is increased. The findings of this study contribute to developments in the textile and sportswear industry

Effect of UV-Curable Inkjet Printing Parameters on Physical, Low-Stress Mechanical, and Aesthetic Properties of Polypropylene Knitted Fabrics

As the use of textile polypropylene (PP) fibers becomes more common in commercial textiles and sportswear, the investigation of the effects of UV-curable ink on the heat-sensitive PP knitted fabrics is crucial to optimize functional clothing design. This study investigated the effects of UV-curable ink on the heat-sensitive PP knitted fabrics when the ink was cured using UV light at room temperature, to avoid degradation of the PP fabric by high temperature, and provided an alternative coloring method for PP fabric used in sportswear. The influences of printing parameters such as the printing distance, number of overprints, and color of ink on fabrics as well as aesthetic, physical, and low-stress mechanical properties in terms of tensile, bending, shearing, surface, and compression were systematically investigated. The results indicated that the physical properties and low-stress mechanical properties of PP fabrics printed with UV-curable ink were significantly affected by the number of overprints and the color of the prints, whereas the color appearance was affected mainly by the number of overprints and the printing distance. In terms of the fabric’s hand value, only 2HB and 2HG5 were significantly affected by the number of overprints and the color of the prints, with the prediction rate exceeding 40 % among the low-stress mechanical properties. The fabric’s hand value was not significantly affected by the thin UV-cured ink film when compared with the fabric itself. Fabric printed in a color with the greatest lightness and the fewest overprints had the lowest fabric weight, thickness, and color difference (ΔE) towards the reference color, in addition to better bending recovery and resilience properties. The new knowledge from this study can provide an alternative coloring method for PP knitted fabric to increase the design variety available to textile designers who use PP fabric. The results from this study contribute to the textile and knitwear design industry

Thermal equations for predicting foot skin temperature

202101 bcrcVersion of RecordPublishe