476 research outputs found
ON THE NUTRITIVE STUDIES OF PANTOTHENIC ACID BY ANTIMETABOLITES II. EFFECT OF ω-METHYL PANTOTHENIC ACID ON THE DEVELOPMENT OF THE CHICK EMBRYO
Effect of Voluntary Exercise and Dietary Protein Levels on Incorporation of ^<14>C-Leucine into Protein by Mice Liver Slices in Vitro
ON THE NUTRITIVE STUDIES OF PANTOTHENIC ACID BY ANTIMETABOLITES I. PANTOTHENIC ACID DEFICIENCY PRODUCED BY (ω-METHYL PANTOTHENIC ACID IN MICE
Transport of Orally Administered Vitamin B_<12> to Embryo and Placenta in vivo and Intrinsic Factor Dependent Vitamin B_<12> Adsorption to Placenta in vitro at Various Stages of Gestation in Rats
Some Properties of Intrinsic Factor-mediated Vitamin B_<12> Adsorption to Intestinal Mucosa Homogenate
Effects of Intrinsic Factor on the Adsorption of Vitamin B_<12> to Organs other than Intestine I). Intrinsic Factor-mediated Vitamin B_<12> Adsorption to Kidney and Placenta
ON THE NUTRITIVE STUDIES OF PANTOTHENIC ACID BY ANTIMETABOLITES III. PANTOTHENIC ACID DEFICIENCY PRODUCED BY ω-METHYL PANTOTHENIC ACID IN RATS
Effects of Intrinsic Factor on the Adsorption of Vitamin B_<12> to Organs other than Intestine II). Adsorption of Vitamin B_<12> to Liver and Effects of Intrinsic Factor
Local cortical pulling-force repression switches centrosomal centration and posterior displacement in C. elegans
Centrosome positioning is actively regulated by forces acting on microtubules radiating from the centrosomes. Two mechanisms, center-directed and polarized cortical pulling, are major contributors to the successive centering and posteriorly displacing migrations of the centrosomes in single-cell–stage Caenorhabditis elegans. In this study, we analyze the spatial distribution of the forces acting on the centrosomes to examine the mechanism that switches centrosomal migration from centering to displacing. We clarify the spatial distribution of the forces using image processing to measure the micrometer-scale movements of the centrosomes. The changes in distribution show that polarized cortical pulling functions during centering migration. The polarized cortical pulling force directed posteriorly is repressed predominantly in the lateral regions during centering migration and is derepressed during posteriorly displacing migration. Computer simulations show that this local repression of cortical pulling force is sufficient for switching between centering and displacing migration. Local regulation of cortical pulling might be a mechanism conserved for the precise temporal regulation of centrosomal dynamic positioning
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