The effect of early tranexamic acid on bleeding, blood product consumption, mortality and length of hospital stay in trauma cases with hemorrhagic shock: a randomized clinical trial

Introduction: Because no medication has been approved for coagulation support in trauma, the current study was aimed to evaluate the effectiveness of intravenous injection of Tranexamic acid (TXA) in patients with acute traumatic bleeding. Methods:  In the current randomized controlled clinical trial, 68 patients with acute bleeding and hemorrhagic shock presentation due to blunt trauma of the abdomen, pelvis, and thorax, randomly assigned into two groups of TXA and placebo. Results :There was no statistically significant difference between the two groups in terms of Systolic blood pressure, pulse rate, Base excess, serum hemoglobin changes, bleeding volume, the incidence of thrombotic events, and the number of deaths (p>0.05). But Systolic blood pressure, pulse rate, base excess, and serum hemoglobin, changed significantly within each group over time(p<0.05). The median time for the length of hospital stay among the TXA group was lower than the Placebo group (6 days versus 10 days, p: 0.004). Also, there was a significant difference between the two groups about the median of pack cell, Platelet consumption, and bleeding Volume (p<0.05). Conclusion  The use of TXA is associated with lower use of blood production and reduced length of hospital stay, however, thrombotic events incidence and mortality rates between the TXA and placebo groups were not different

A statistical-based criterion for incipient fault detection in underground power cables established on voltage waveform characteristics

The incipient faults which mainly occur due to the electric arc occurrence in the power cables with insulation defects are hardly detectable by the conventional protective relays, and over time can develop into a permanent fault in the system. Employing Kalman filter, this paper puts forward a method to detect the incipient faults and to discriminate them from other similar incidents in the power system. The proposed method is established on the comparison between the waveform of the measured voltage and fundamental component of the measured voltage, estimated by Kalman filter algorithm in the sending end of the cable during the fault. Employing the difference between the measured and estimated waveforms, the incipient fault detection and discrimination are carried out within two stages. In the first stage, event detection is relegalized by comparing the standard deviation of the obtained error with a certain threshold. The second stage is conducted to find the incipient fault based on the non-attenuating characteristic and quasi-periodic nature of the incipient fault. The feasibility of the proposed method is verified through computer simulation using four different electric arc models and also the acquired experimental data from real incipient faults

A similarity-based framework for incipient fault detection in underground power cables

Incipient faults are known as the faults mainly occurring on the junctions of underground power cables. Clearing quickly, these faults are difficult to detect by conventional protection equipment, leading to insulation degradation and permanent fault in the power cable over time. In this paper, employing similarity functions, a new method is put forward to distinguish the existing fault from other similar events with both high speed and accuracy. The proposed algorithm consists of a two-stages algorithm including change detection, disturbance identification, and fault detection. The proposed method performs the calculation on the voltage signal that is recorded at the sending end of the line. The cross-correlation function is employed for identifying change detection and determining disturbance time. Afterward, using sinusoidal curve fitting, the algorithm can distinguish the incipient fault from sudden load change, capacitor switching, and harmonic load. The accuracy of the proposed approach is verified by some experimental data and 6272 simulation data obtained from four types of well-known arc models, capacitor switching, and also load variations

Potentially fatal atrium perforation due to right jugular vein catheterization recognized by venography: A case report

Abstract Central venous catheters are the prevalent path for dialysis. Our case was a 54‐years‐old male with a new case of end‐stage renal disease with a complaint of right jugular hemodialysis catheter dysfunction. In our case, the early dysfunctional catheter should be evaluated with contrast studies to achieve accurate information