17 research outputs found
Optimization and degradation simulation of magnesium alloy stent:experimental verification
Experimental data confirm numerical modeling of the degradation process of magnesium alloys stents
Biodegradable magnesium alloy stents (MAS) could present improved long-term clinical performances
over commercial bare metal or drug-eluting stents. However, MAS were found to show limited mechanical
support for diseased vessels due to fast degradation. Optimizing stent design through finite element
analysis (FEA) is an efficient way to improve such properties. Following previous FEA works on design
optimization and degradation modeling of MAS, this work carried out an experimental validation for
the developed FEA model, thus proving its practical applicability of simulating MAS degradation. Twelve
stent samples of AZ31B were manufactured according to two MAS designs (an optimized one and a conventional
one), with six samples of each design. All the samples were balloon expanded and subsequently
immersed in D-Hanks’ solution for a degradation test lasting 14 days. The experimental results showed
that the samples of the optimized design had better corrosion resistance than those of the conventional
design. Furthermore, the degradation process of the samples was dominated by uniform and stress corrosion.
With the good match between the simulation and the experimental results, the work shows that
the FEA numerical modeling constitutes an effective tool for design and thus the improvement of novel
biodegradable MAS