International Nuclear Medicine Consensus on the Clinical Use of Amyloid Positron Emission Tomography in Alzheimer's Disease.

Alzheimer's disease (AD) is the main cause of dementia, with its diagnosis and management remaining challenging. Amyloid positron emission tomography (PET) has become increasingly important in medical practice for patients with AD. To integrate and update previous guidelines in the field, a task group of experts of several disciplines from multiple countries was assembled, and they revised and approved the content related to the application of amyloid PET in the medical settings of cognitively impaired individuals, focusing on clinical scenarios, patient preparation, administered activities, as well as image acquisition, processing, interpretation and reporting. In addition, expert opinions, practices, and protocols of prominent research institutions performing research on amyloid PET of dementia are integrated. With the increasing availability of amyloid PET imaging, a complete and standard pipeline for the entire examination process is essential for clinical practice. This international consensus and practice guideline will help to promote proper clinical use of amyloid PET imaging in patients with AD

Multimode mean-field model for the quantum phase transition of a Bose-Einstein condensate in an optical resonator

We develop a mean-field model describing the Hamiltonian interaction of ultracold atoms and the optical field in a cavity. The Bose-Einstein condensate is properly defined by means of a grand-canonical approach. The model is efficient because only the relevant excitation modes are taken into account. However, the model goes beyond the two-mode subspace necessary to describe the self-organization quantum phase transition observed recently. We calculate all the second-order correlations of the coupled atom field and radiation field hybrid bosonic system, including the entanglement between the two types of fields.Comment: 10 page