12 research outputs found
Solutions of a particle with fractional -potential in a fractional dimensional space
A Fourier transformation in a fractional dimensional space of order \la
(0<\la\leq 1) is defined to solve the Schr\"odinger equation with Riesz
fractional derivatives of order \a. This new method is applied for a particle
in a fractional -potential well defined by V(x) =-
\gamma\delta^{\la}(x), where and \delta^{\la}(x) is the
fractional Dirac delta function. A complete solutions for the energy values and
the wave functions are obtained in terms of the Fox H-functions. It is
demonstrated that the eigen solutions are exist if 0< \la<\a. The results for
\la= 1 and \a=2 are in exact agreement with those presented in the standard
quantum mechanics
Fission Yeast F-box Protein Pof3 Is Required for Genome Integrity and Telomere Function
The Skp1-Cullin-1/Cdc53-F-box protein (SCF) ubiquitin ligase plays an important role in various biological processes. In this enzyme complex, a variety of F-box proteins act as receptors that recruit substrates. We have identified a fission yeast gene encoding a novel F-box protein Pof3, which contains, in addition to the F-box, a tetratricopeptide repeat motif in its N terminus and a leucine-rich-repeat motif in the C terminus, two ubiquitous protein–protein interaction domains. Pof3 forms a complex with Skp1 and Pcu1 (fission yeast cullin-1), suggesting that Pof3 functions as an adaptor for specific substrates. In the absence of Pof3, cells exhibit a number of phenotypes reminiscent of genome integrity defects. These include G2 cell cycle delay, hypersensitivity to UV, appearance of lagging chromosomes, and a high rate of chromosome loss. pof3 deletion strains are viable because the DNA damage checkpoint is continuously activated in the mutant, and this leads to G2 cell cycle delay, thereby preventing the mutant from committing lethal mitosis. Pof3 localizes to the nucleus during the cell cycle. Molecular analysis reveals that in this mutant the telomere is substantially shortened and furthermore transcriptional silencing at the telomere is alleviated. The results highlight a role of the SCF(Pof3) ubiquitin ligase in genome integrity via maintaining chromatin structures