Novel 7-Aryliden-3,3a,4,5,6,7-(hexahydro-5-(2-ethoxyethyl)-2-phenyl- 3-aryl-2H-pyrazolo[4,3-c]pyridine Hydrochloride: Synthesis and Structure

A Claisen-Schmidt type reaction of 1-(2-ethoxyethyl)piperidin-4-one with differ­ent aromatic aldehydes led to corresponding dienones with a yield of 65‒71%. 7-Arylidene-3,3a,4,5,6,7-(hexahydro-5-(2-ethoxyethyl)-2-phenyl-3-aryl-2H-pyrazolo[4,3-c]pyridines were synthesized by heterocyclization of 3,5-dia­rylidene-piperidin-4-ones with phenylhydrazine hydrochloride in methanol at 70 °C over 4‒6 h. The X-ray crystal structure determination of 7-(p-methoxy­benzyliden)-3,3a,4,5,6,7-(hexahydro-5-(2-ethoxyethyl)-2-phenyl-3-(p-methoxy­phenyl)-2H-pyrazolo[4,3-c]pyridine hydrochloride (the deposition number is CCDC 862410) was completed. The piperidine and pyrazoline rings are close to a chair and envelope conformations, respectively.

Immobilization of Analgetic AB-101 into Calcium Alginate Gels

A new analgetic drug AB-101 has been immobilized into Ca2+-alginate gel beads with average diameter of 1 mm. A series of the alginate gel contains with various mannuronic/guluronic (M/G) ratios has been chosen to control the diffusion of the drug. Release of the drug from the alginate gel beads into physiological solutions consisting of sodium ions has been examined. A discontinuous time of the Fickian diffusion of the drug depending on M/G ratio was followed by a burst release of the remaining drugs. The burst release was due to a swift disintegration of Ca2+-alginate with exchange on sodium ions. The preceding discontinuous lag time promotes a free dissociate exchange of sodium-calcium ions in M units, while the burst disintegration leads to fast dissociation of G units. The lag time can be control by M/G ratio of Ca2+-alginate gels. The lag time increases if a content of the M units decreases. The increase of M units was led to more extensive swelling of the gel beads. Such way could be promising for a controlled drug delivery or the use in implants with controlled drug effect

Erarbeitung von Bau- und Pruefgrundsaetzen fuer Amalgamabscheider

With 2 refs.SIGLEAvailable from TIB Hannover: RN8908(92-001) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman

Moeglichkeiten einer Reform der gesetzlichen Krankenversicherung in der Bundesrepublik Deutschland

SIGLEBibliothek Weltwirtschaft Kiel YY11512 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman

Beleuchtungsmodelle zur realitaetsnahen Darstellung dreidimensionaler Objekte in der Computer Graphics

SIGLECopy held by FIZ Karlsruhe; available from UB/TIB Hannover / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman

Ueber Aspekte der visuellen Wahrnehmung und der optischen Eigenschaften idealer Oberflaechen

SIGLECopy held by FIZ Karlsruhe; available from UB/TIB Hannover / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman

Kaehlerian E-spinors

SIGLEAvailable from TIB Hannover: RR 1596(183) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman

Holomorphic spinors and the Dirac equation

A closed spin Kaehler manifold of positive scalar curvature with smallest possible first eigenvalue of the Dirac operator is characterized by holomorphic spinors. It is shown that on any spin Kaehler-Einstein manifold each holomorphic spinor is a finite sum of eigenspinors of the square of the Dirac operator. Vanishing theorems for homomorphic spinors are proved. (orig.)SIGLEAvailable from TIB Hannover: RR 1596(290) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman

Erarbeitung von Beurteilungsverfahren fuer angeklebte Fassadenbekleidungen Abschlussbericht

TIB: RN 8423 (13) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman

Entwicklung eines optoelektronischen Messwertaufnehmers zur beruehrungslosen Messung kleiner Wege Schlussbericht zum Forschungsvorhaben

TIB: AC 8642 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman