82 research outputs found

    Curved Tails in Polymerization-Based Bacterial Motility

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    The curved actin ``comet-tail'' of the bacterium Listeria monocytogenes is a visually striking signature of actin polymerization-based motility. Similar actin tails are associated with Shigella flexneri, spotted-fever Rickettsiae, the Vaccinia virus, and vesicles and microspheres in related in vitro systems. We show that the torque required to produce the curvature in the tail can arise from randomly placed actin filaments pushing the bacterium or particle. We find that the curvature magnitude determines the number of actively pushing filaments, independent of viscosity and of the molecular details of force generation. The variation of the curvature with time can be used to infer the dynamics of actin filaments at the bacterial surface.Comment: 8 pages, 2 figures, Latex2

    Developing a Citizen Social Science approach to understand urban stress and promote wellbeing in urban communities

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    This paper sets out the future potential and challenges for developing an interdisciplinary, mixed-method Citizen Social Science approach to researching urban emotions. It focuses on urban stress, which is increasingly noted as a global mental health challenge facing both urbanised and rapidly urbanising societies. The paper reviews the existing use of mobile psychophysiological or biosensing within urban environments—as means of ‘capturing’ the urban geographies of emotions. Methodological reflections are included on primary research using biosensing in a study of workplace and commuter stress for university employees in Birmingham (UK) and Salzburg (Austria) for illustrative purposes. In comparing perspectives on the conceptualisation and measurement of urban stress from psychology, neuroscience and urban planning, the difficulties of defining scientific constructs within Citizen Science are discussed to set out the groundwork for fostering interdisciplinary dialogue. The novel methods, geo-located sensor technologies and data-driven approaches to researching urban stress now available to researchers pose a number of ethical, political and conceptual challenges around defining and measuring emotions, stress, human behaviour and urban space. They also raise issues of rigour, participation and social scientific interpretation. Introducing methods informed by more critical Citizen Social Science perspectives can temper overly individualised forms of data collection to establish more effective ways of addressing urban stress and promoting wellbeing in urban communities

    �ber die Konstitution der prosthetischen Gruppe des Cytochroms c

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    �ber eisenhaltige Fermente

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    Eine neue Methode zur quantitaven Analyse von Aminos�uregemischen

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    Ultrasonic spectroscopy in p-type silicon

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    From ultrasonic resonant absorption over a wide frequency range we have determined the distribution of the energy splittings of the acceptor ground state in very pure Si(B) crystals. The measured distributions with maxima of the order of 10 μeV fit well to the expected electric field distribution from the ≃ 1012 cm-3 residual donors. The critical intensity for saturating the resonance attenuation has been measured in crystals of various acceptor concentrations and as a function of temperature. Although the average distance of acceptor atoms is much greater than the Bohr-radius of the bound defect-electrons, relaxation times are found to be shortened by the acceptor-acceptor interaction.On a déterminé la distribution des séparations en énergie des niveaux de l'état fondamental de l'accepteur dans des cristaux Si(B) très purs en mesurant l'absorption résonnante ultrasonore dans une gamme importante de fréquences. Les distributions mesurées se comparent bien avec les distributions attendues des champs électriques des ≃ 10 12 cm-3 donneurs résiduels. On a mesuré l'intensité critique pour saturer l'atténuation résonnante dans des cristaux avec différentes concentrations d'accepteurs et en fonction de la température. Bien que la distance moyenne des accepteurs soit beaucoup plus grande que le rayon de Bohr des trous liés on trouve que les temps de relaxation sont raccourcis par l'interaction accepteur-accepteur
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