Поверхностная ионизация органических соединений азота, серы, фосфора и мышьяка

A research facility and a technique for measuring the basic parameters of surface ionization of organic compounds were developed. For a series of organic compounds of nitrogen, sulfur, phosphorus, and arsenic the key parameters of surface ionization were determined.Разработана экспериментальная установка и методика определения основных параметров поверхностной ионизации органических соединений. Для ряда органических веществ на основе азота, серы, фосфора, мышьяка определены механизм и основные параметры поверхностной ионизации

System Approach to the Development of Intelligent Complexes of Oncological Diagnostics

The system approach to the development of intellectual complexes in cancer diagnosis are discussed in the article. Distinctive features of this approach: the participation of pathologist at the stage of description of recognizable images (the description is based on traditional assessments of quality informative features of tumors); the set of the most similar probabilistic diagnoses is forming on the classification stage of recognition; final histological diagnosis is made by pathologist. The proposed approach has been successfully tested in clinical practice. Keywords: image processing, image description, image classification, pattern recognition, qualitative attributes of tumor images, interactive recognition, cancer diagnosis, decision support syste

Surface ionization of organic compounds on the basis of nitrogen, sulfur, phosphorus, and arsenic

A research facility and a technique for measuring the basic parameters of surface ionization of organic compounds were developed. For a series of organic compounds of nitrogen, sulfur, phosphorus, and arsenic the key parameters of surface ionization were determined

Metabolic profiling of Peperoni di Senise PGI bell peppers with ultra-high resolution absorption mode Fourier transform ion cyclotron resonance mass spectrometry

Bell peppers (genus Capsicum) are an excellent source of health-related compounds, such as ascorbic acid (vitamin C), carotenoids (provitamin A), tocopherols (vitamin E), flavonoids and capsaicinoids. These compounds are known for their biological activities, including antioxidant, anti-inflammatory and anticarcinogenic properties. Over the past decade, there has been an increasing number of studies focused on metabolite profiling of bell peppers. However, none of the direct analysis methods exploited in these studies were capable of simultaneously detecting compounds belonging to more than four metabolite classes (and possible derivatives of model compounds) present in bell peppers, i.e. mainly amino acids, sugars, polyphenols and organic acids. We have attempted to profile a higher number of metabolite classes by performing a direct-injection analysis with a Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS), on Peperoni di Senise bell peppers (Capsicum annuum L.). These bell peppers are a typical food product cultivated in Basilicata (Southern Italy), protected with a protected geographical indication (PGI) quality mark and known for their unique taste. To increase the performance of the FT-ICR MS method, we processed the recorded time-domain ion signals (transients) into the absorption mode FT-ICR mass spectra. The latter was achieved by the use of the dedicated software package, AutoVectis Pro. Mass spectral representation in absorption mode produced a more comprehensive description of the metabolic profile of Peperoni di Senise PGI by improving results reliability via artifacts removal and identifying a higher number of compounds

Temperature profile for glacial ice at the South Pole: Implications for life in a nearby subglacial lake

Airborne radar has detected ≈100 lakes under the Antarctic ice cap, the largest of which is Lake Vostok. International planning is underway to search in Lake Vostok for microbial life that may have evolved in isolation from surface life for millions of years. It is thought, however, that the lakes may be hydraulically interconnected. If so, unsterile drilling would contaminate not just one but many of them. Here we report measurements of temperature vs. depth down to 2,345 m in ice at the South Pole, within 10 km from a subglacial lake seen by airborne radar profiling. We infer a temperature at the 2,810-m deep base of the South Pole ice and at the lake of −9°C, which is 7°C below the pressure-induced melting temperature of freshwater ice. To produce the strong radar signal, the frozen lake must consist of a mix of sediment and ice in a flat bed, formed before permanent Antarctic glaciation. It may, like Siberian and Antarctic permafrost, be rich in microbial life. Because of its hydraulic isolation, proximity to South Pole Station infrastructure, and analog to a Martian polar cap, it is an ideal place to test a sterile drill before risking contamination of Lake Vostok. From the semiempirical expression for strain rate vs. shear stress, we estimate shear vs. depth and show that the IceCube neutrino observatory will be able to map the three-dimensional ice-flow field within a larger volume (0.5 km(3)) and at lower temperatures (−20°C to −35°C) than has heretofore been possible