25 research outputs found
Radiatively induced leptogenesis in a minimal seesaw model
We study the possibility that the baryon asymmetry of the universe is
generated in a minimal seesaw scenario where two right-handed Majorana
neutrinos with degenerate masses are added to the standard model particle
content. In the usual framework of thermal leptogenesis, a nonzero
asymmetry can be obtained through the mass splitting induced by the running of
the heavy Majorana neutrino masses from their degeneracy scale down to the
seesaw scale. Although, in the light of the present neutrino oscillation data,
the produced baryon asymmetry turns out to be smaller than the experimental
value, the present mechanism could be viable in simple extensions of the
standard model.Comment: 6 pages, 2 figures, uses RevTeX4, calculations improved, comments
adde
Quintessential Kination and Leptogenesis
Thermal leptogenesis induced by the CP-violating decay of a right-handed
neutrino (RHN) is discussed in the background of quintessential kination, i.e.,
in a cosmological model where the energy density of the early Universe is
assumed to be dominated by the kinetic term of a quintessence field during some
epoch of its evolution. This assumption may lead to very different
observational consequences compared to the case of a standard cosmology where
the energy density of the Universe is dominated by radiation. We show that,
depending on the choice of the temperature T_r above which kination dominates
over radiation, any situation between the strong and the super--weak wash--out
regime are equally viable for leptogenesis, even with the RHN Yukawa coupling
fixed to provide the observed atmospheric neutrino mass scale ~ 0.05 eV. For M<
T_r < M/100, i.e., when kination stops to dominate at a time which is not much
later than when leptogenesis takes place, the efficiency of the process,
defined as the ratio between the produced lepton asymmetry and the amount of CP
violation in the RHN decay, can be larger than in the standard scenario of
radiation domination. This possibility is limited to the case when the neutrino
mass scale is larger than about 0.01 eV. The super--weak wash--out regime is
obtained for T_r << M/100, and includes the case when T_r is close to the
nucleosynthesis temperature ~ 1 MeV. Irrespective of T_r, we always find a
sufficient window above the electroweak temperature T ~ 100 GeV for the
sphaleron transition to thermalize, so that the lepton asymmetry can always be
converted to the observed baryon asymmetry.Comment: 13 pages, 8 figure
Kahler potentials for the MSSM inflation and the spectral index
Recently it has been argued that some of the fine-tuning problems of the MSSM
inflation associated with the existence of a saddle point along a flat
direction may be solved naturally in a class of supergravity models. Here we
extend the analysis and show that the constraints on the Kahler potentials in
these models are considerably relaxed when the location of the saddle point is
treated as a free variable. We also examine the effect of supergravity
corrections on inflationary predictions and find that they can slightly alter
the value of the spectral index. As an example, for flat direction field values
we find while the
prediction of the MSSM inflation without any corrections is .Comment: 13 pages, one figure. Typos corrected and a reference adde
Charged Lepton Electric Dipole Moments from TeV Scale Right-handed Neutrinos
We study the connection between charged lepton electric dipole moments,
, and seesaw neutrino mass generation in a simple two Higgs
doublet extension of the Standard Model plus three right-handed neutrinos (RHN)
, . For RHN with hierarchical masses and at least one with mass
in the 10 TeV range we obtain the upper bounds of
e-cm and e-cm. Our scenario favors the normal
mass hierarchy for the light neutrinos. We also calculated the cross section
for e^-e^- \ra W^- W^- in a high luminosity collider with constraints from
neutrinoless double beta decay of nuclei included. Among the rare muon decay
experiments we find that \mu\ra e\gamma is most sensitive and the upper limit
is .Comment: references added, typos correcte
Astrophysical and Cosmological Implications of Large Volume String Compactifications
We study the spectrum, couplings and cosmological and astrophysical
implications of the moduli fields for the class of Calabi-Yau IIB string
compactifications for which moduli stabilisation leads to an exponentially
large volume V ~ 10^{15} l_s^6 and an intermediate string scale m_s ~
10^{11}GeV, with TeV-scale observable supersymmetry breaking. All K\"ahler
moduli except for the overall volume are heavier than the susy breaking scale,
with m ~ ln(M_P/m_{3/2}) m_{3/2} ~ (\ln(M_P/m_{3/2}))^2 m_{susy} ~ 500 TeV and,
contrary to standard expectations, have matter couplings suppressed only by the
string scale rather than the Planck scale. These decay to matter early in the
history of the universe, with a reheat temperature T ~ 10^7 GeV, and are free
from the cosmological moduli problem (CMP). The heavy moduli have a branching
ratio to gravitino pairs of 10^{-30} and do not suffer from the gravitino
overproduction problem. The overall volume modulus is a distinctive feature of
these models and is an M_{planck}-coupled scalar of mass m ~ 1 MeV and subject
to the CMP. A period of thermal inflation can help relax this problem. This
field has a lifetime ~ 10^{24}s and can contribute to dark matter. It may be
detected through its decays to 2\gamma or e^+e^-. If accessible the e^+e^-
decay mode dominates, with Br(\chi \to 2 \gamma) suppressed by a factor
(ln(M_P/m_{3/2}))^2. We consider the potential for detection of this field
through different astrophysical sources and find that the observed gamma-ray
background constrains \Omega_{\chi} <~ 10^{-4}. The decays of this field may
generate the 511 keV emission line from the galactic centre observed by
INTEGRAL/SPI.Comment: 31 pages, 2 figures; v2. refs adde
Suppression of the c-erbB-2 gene product decreases transformation abilities but not the proliferation and secretion of proteases of SK-OV-3 ovarian cancer cells
The overexpression of the c-erbB-2 oncogene product has been reported in approximately 20–30% of human ovarian cancers and has been correlated with a poor prognosis in ovarian cancer patients. To investigate the function of p185c-erbB-2 in human ovarian cancer cells, a c-erbB-2-specific single-chain antibody (scFv-5R) was expressed in the c-erbB-2-overexpressing SK-OV-3 cell line using a retroviral expression vector. Eight individual clones expressing the single-chain antibody were isolated. These clones have a prominent retention of the cell surface p185c-erbB-2. In this study we compared the proliferation rate, the anchorage-independent growth, the secretion of matrix metalloproteases and of the urokinase-type plasminogen activator. The clones expressing the c-erbB-2 single-chain antibody, the control cells harbouring the empty vector and the parental SK-OV-3 cells they all had similar proliferation rates in the presence of 10% serum and secreted similar amounts of matrix metalloproteases and of the urokinase-type plasminogen activator. However, the expression of the c-erbB-2 oncogene product offers a strong growth advantage under serum-reduced conditions with 1% serum. In contrast to the parental SK-OV-3 and empty vector control cells, the scFv-5R-expressing clones were not able to grow anchorage-independently. These findings suggest that c-erbB-2 enhances transformation abilities of SK-OV-3 ovarian cancer cells without affecting the secretion of proteases and the proliferation of SK-OV-3 ovarian cancer cells in the presence of high concentrations of serum. © 1999 Cancer Research Campaig
Lectures on Cosmic Inflation and its Potential Stringy Realizations
These notes present a brief introduction to Hot Big Bang cosmology and Cosmic
Inflation, together with a selection of some recent attempts to embed inflation
into string theory. They provide a partial description of lectures presented in
courses at Dubrovnik in August 2006, at CERN in January 2007 and at Cargese in
August 2007. They are aimed at graduate students with a working knowledge of
quantum field theory, but who are unfamiliar with the details of cosmology or
of string theory.Comment: 68 pages, lectures given at Dubrovnik, Aug 2006; CERN, January 2007;
and Cargese, Aug 200