Flüssigkeits-Chromatographie an Triacetylcellulose 13: Triacetylcellulose on silica compared with non-dilute triacetylcellulose I as a high-performance liquid chromatographic sorbent

Triacetylcellulose coated on silica is a novel HPLC sorbent introduced for the separation of enantiomers. A comparison of enantioselectivities α, and resolutions R5 of this material with known pure triacetylcellulose I shows considerable differences. From X-ray wideangle diffraction it is suggested that the novel sorbent also consists of the triacetylcellulose modification I, but its degree of crystallinity is probably lower than that of the non-dilute sorbent. The advantages of the two stationary phases are discussed

Chiroptical Detection after Liquid Chromatography 1: Chiroptical detection. Novel possibilities of its application to enantiomers

Polarimetric and/or circular dichroic detection of enantiomers after liquid chromatography on optically active sorberts has been used for the following purposes: determination of enantiomeric purity in spite of peak overlap, investigation of enantiomerization during chromatography, monitoring of racemizations and recording of circular dichrograms without preparative enrichment of enantiomers. Novel examples for all applications are give. The general prospects for chiroptical detection are discussed