A STUDY ON EVALUATION OF POTASSIUM ABNORMALITIES IN A TERTIARY CARE HOSPITAL

Objective: To study the occurrence, causes, predisposing factors and management of potassium abnormalities in a tertiary care hospital. Methods: Inour studywhich was for aduration of six months, we recorded patient demographics, electrolyte levels, complete blood picture, liver function tests, renal parameters, comorbid conditions,medication reconciliation and electro cardio gram (ECG) changes. The data was analyzed to find out the cause for potassium abnormality and was categorize based on their severity. Results:A total of 200 cases of potassium abnormalities was normalized during the study period. We observed158(80%)cases with hypokalemia, 37 (17%) cases with hyperkalemia and 5 (3%) caseswith subsequentPotassium abnormalities. We observed the majority of hypokalemiaarewith disease induced 87(55.06%) cases and 118 (74.0%)cases were with mild hypokalemia. Syruppotassium chloride was usedto normalize the serum potassium levels. Majority of the hyperkalemia cases were disease induced and was found in 19(51.35%)cases and 22 (59.45%) casescome under mild categorywhich was managed with injection calciumgluconate. Conclusion: Hypokalemia was the most common potassium abnormality seen in hospitalized patients.Disease inducedpotassium abnormalitieswas found to be more common in both hypo and hyperkalemia. The potassium levels were normalized with no major negative outcomes. Continuous monitoring of electrolyte levels is required for the patient to prevent further complications

Antimicrobial and Environmental Applications of Inorganic Nanoparticles Synthesised from Plants

Nanoscale materials are widely used in many fields including medicine, engineering, and the environment that focuses on the synthesis of nano dimensional particles is a timely topic. Nanomaterials synthesized by chemical approaches have intended effects on the environment and human health. In response to these challenges, plant-mediated synthesis of inorganic nanoparticles has been a highly innovative research area over the last decade. Aqueous and solvent extracts have been employed as efficient resources in synthesis-controlled nanostructures and the fabrication of various nanomaterials. The present article unveils the possible role of plant biomolecules including amino acids, aldehydes, terpenoids, ketones, tannins, and phenolics in the reduction and stabilization of various metal and metal oxide nanoparticles. The green synthesized nanoparticles evolved as efficient alternative agents in solving the serious threats faced in the field of biomedical, energy conversion, environment, automobiles, electronics, and optical. Moreover, catalytic, and antimicrobial applications of green nanoparticles are also critically discussed

Mycosynthesis of CuO Nanoparticles Using Aspergillus niger and Their Bioefficiency against Human Pathogens

In the present study, copper oxide (CuO) nanoparticles were biosynthesized from an Aspergillus niger cell-free extract (CFE), and several optimal operating parameters that affected the formation and dimensions of the CuO nanoparticles were determined, as follows: 15 mmol/L metal salt and 90 mL of CFE at room temperature for 24 h, to achieve an average size of 77 nm. Spectroscopic studies revealed an association between alcohol, alkene, and amine functional groups and the grain-shaped CuO nanoparticles. The elemental composition of the nanoparticles was confirmed by energy dispersive X-ray spectroscopy (EDX) data. Mycogenic CuO nanoparticles exhibited excellent antibacterial activity against Gram-positive bacterial species compared with Gram-negative bacterial species, i.e., Streptococcus pneumoniae MTCC 2672, Staphylococcus aureus MTCC 737, Micrococcus luteus MTCC 11948, Pseudomonas aeruginosa MTCC 424, and Escherichia coli MTCC 443, at 200 mg/mL, with inhibition zones of 9.2, 8.3 7.7, 7.2, and 6.1 mm, respectively. Finally, myogenic CuO nanoparticles exhibited good antifungal activity against Aspergillus fumigatus and Aspergillus versicolor

On the contribution of boundaries towards strength in oxygen free high conductivity copper subjected to repetitive upsetting – extrusion

Oxygen free high conductivity (OFHC) copper was subjected to 1, 5, 10, 15 and 20 cycles of repetitive upsetting and extrusion (RUE) process at room temperature. Microstructure and microhardness in the RUE processed material were evaluated at specific locations and correlated with the equivalent plastic strain. The microhardness of the material was found to be independent of strain or number of RUE cycles at certain locations whereas it exhibited strain softening behaviour at certain locations even though significant grain refinement was achieved. This difference in behaviour is attributed to the varied strength contribution from different types of boundaries present in the material after deformation

Dataset for: Selective Measurement of 1H-1H Scalar Couplings from Crowded Chemical Shift Regions: Combined Pure Shift and Spin-Echo Modulation approach

JHH scalar couplings carry rich structural information and their measurements are fundamental in the 1H NMR based elucidation of small and medium molecules, which, however are hampered in the presence of large J-coupling network. Further, enhanced spectral resolution is often essential for precise determination of a specific set of 1H-1H J-couplings amongst the complex J-multiplets. In the light of the recent advancements in homodecoupling pure shift strategies, here we report absorption mode, band-selective refocused pure shift spin-echo (BSR-PSSE) method, which helps in determining 1H-1H J-couplings from crowded spectral regions. The importance of the present BSR-PSSE experiment is exemplified for two steroid molecules, estradiol and testosterone