Bose-Einstein Condensation of Erbium

We report on the achievement of Bose-Einstein condensation of erbium atoms and on the observation of magnetic Feshbach resonances at low magnetic field. By means of evaporative cooling in an optical dipole trap, we produce pure condensates of $^{168}$Er, containing up to $7 \times 10^{4}$ atoms. Feshbach spectroscopy reveals an extraordinary rich loss spectrum with six loss resonances already in a narrow magnetic-field range up to 3 G. Finally, we demonstrate the application of a low-field Feshbach resonance to produce a tunable dipolar Bose-Einstein condensate and we observe its characteristic d-wave collapse.Comment: 4 pages, 3 figure

Narrow-line magneto-optical trap for erbium

We report on the experimental realization of a robust and efficient magneto-optical trap for erbium atoms, based on a narrow cooling transition at 583nm. We observe up to $N=2 \times 10^{8}$ atoms at a temperature of about $T=15 \mu K$. This simple scheme provides better starting conditions for direct loading of dipole traps as compared to approaches based on the strong cooling transition alone, or on a combination of a strong and a narrow kHz transition. Our results on Er point to a general, simple and efficient approach to laser cool samples of other lanthanide atoms (Ho, Dy, and Tm) for the production of quantum-degenerate samples

Polyphonic internationalism: the Lucie Zimmern School of International Studies

This article recovers the musician, pedagogue, institution-builder, and intellectual Lucie Zimmern (1875–1963). Together with her husband Alfred, a canonical international thinker, Zimmern founded and ran the Geneva School of International Studies (1923–1939), where she outlined and taught the principles of what we term ‘polyphonic internationalism’ to hundreds of students from across the globe: the musical texture of polyphony was an ordering principle for a world which had yet come to terms with the reality of human diversity. Zimmern’s musical formation, her complex racial, religious, and national identity, combined with her experience as a private cultural diplomat of the Anglo-French Entente Cordiale, shaped her distinctive analysis of international politics which she disseminated in academic debates, written works, and public lectures. We analyse the genesis and claims of polyphonic internationalism, overtly a culturally relativist concept that sought to reconcile national and cultural self-determination with the hierarchies of empire. Lucie Zimmern’s trajectory as a thinker and her experience as a ‘wife of the canon’ reveals the gendered politics of intellectual production in the early academic field of international relations where the boundaries between the feminised domains of culture and internationalist pedagogy, and the soon-to-be masculinised academic, and ‘scientific’ study of international relations remained surprisingly permeable

Definitive chemoradiotherapy in patients with squamous cell cancers of the head and neck-results from an unselected cohort of the clinical cooperation group "Personalized Radiotherapy in Head and Neck Cancer".

Background Definitive chemoradiotherapy (dCRT) is a standard treatment for patients with locally advanced head and neck cancer. There is a clinical need for a stratification of this prognostically heterogeneous group of tumors in order to optimize treatment of individual patients. We retrospectively reviewed all patients with head and neck squamous cell carcinoma (HNSCC) of the oral cavity, oropharynx, hypopharynx, or larynx, treated with dCRT from 09/2008 until 03/2016 at the Department of Radiation Oncology, LMU Munich. Here we report the clinical results of the cohort which represent the basis for biomarker discovery and molecular genetic research within the framework of a clinical cooperation group. Methods Patient data were collected and analyzed for outcome and treatment failures with regard to previously described and established risk factors. Results We identified 184 patients with a median follow-up of 65 months and a median age of 64 years. Patients received dCRT with a median dose of 70 Gy and simultaneous chemotherapy in 90.2% of cases, mostly mitomycin C / 5-FU in concordance with the ARO 95-06 trial. The actuarial 3-year overall survival (OS), local, locoregional and distant failure rates were 42.7, 29.8, 34.0 and 23.4%, respectively. Human papillomavirus-associated oropharynx cancer (HPVOPC) and smaller gross tumor volume were associated with significantly improved locoregional tumor control rate, disease-free survival (DFS) and OS in multivariate analysis. Additionally, lower hemoglobin levels were significantly associated with impaired DFS und OS in univariate analysis. The extent of lymph node involvement was associated with distant failure, DFS and OS. Moreover, 92 patients (50%) of our cohort have been treated in concordance with the ARO 95-06 study, corroborating the results of this study. Conclusion Our cohort is a large unselected monocentric cohort of HNSCC patients treated with dCRT. Tumor control rates and survival rates compare favorably with the results of previously published reports. The clinical data, together with the available tumor samples from biopsies, will allow translational research based on molecular genetic analyses