Evaluation of Rubber band ligation technique for Internal Haemorrhoids

Introduction: Hemorrhoids are masses or clumps or “cushions” of tissues consisting of muscle and elastic fibres with enlarged, bulging blood vessels and surrounding supporting tissues present in the anal canal of an individual suffering from the disease. It is one of the common reasons for surgical OPD visit. In this study we tried to find out effectiveness of Ring band ligation technique 1st degree, 2nd degree & some of the 3rd degree hemorrhoids. Methods: All the patients coming to surgical OPD of tertiary care teaching hospital from June 2012 to December 2013 and diagnosed as a case of Hemorrhoids were included in study. Proctoscopic examination found to have first-, second-, and non-bulky, non edematous third-degree haemorrhoids were included for band ligation. Results: Out of total patients 202 were males and 145 were females. Bleeding per rectum (52%), discomfort during defecation (58%) and constipation (47%) were most common symptoms. Most common post-ligation/residual symptoms were bleeding (32 %), pain & discomfort (29.4 %) & constipation (21 %).70 % of patients are cured and 14 % have shown significant improvement. Conclusion: Rubber band ligation as first line treatment for 2nd degree lesion, however for 3rd degree lesion Open hemorrhoidectomy is always better

Scrotal Calcinosis Presenting As Nodular Masses : A Report Of 4 Cases

Scrotal calcinosis is characterized by multiple nodular masses within the scrotal skin, slowly increasing in size. The pathogenesis is obscure and is viewed by many to be idiopathic or can result from dystrophic calcification of epidermal cysts. We report 4 cases of scrotal calcinosis presenting as multiple nodules over scrotal skin

Cutaneous Rhinosporidiosis

Rhinosporidiosis, an infection caused by Rhinosporidium seeberi, predominatly causes lesions in nose followed by conjunctiva. Rarely the other mucocutaneous junctions are involved. Cutaneous rhinosporidiosis is infrequent and is associated with adjacent mucocutaneous disease. We present a case of cutaneous rhinosporidiosis which was not associated with disease elsewhere in the body and is very rare

Robust tracking with interest points: A sparse representation approach

Visual tracking is an important task in various computer vision applications including visual surveillance, human computer interaction, event detection, video indexing and retrieval. Recent state of the art sparse representation (SR) based trackers show better robustness than many of the other existing trackers. One of the issues with these SR trackers is low execution speed. The particle filter framework is one of the major aspects responsible for slow execution, and is common to most of the existing SR trackers. In this paper,(1) we propose a robust interest point based tracker in l(1) minimization framework that runs at real-time with performance comparable to the state of the art trackers. In the proposed tracker, the target dictionary is obtained from the patches around target interest points. Next, the interest points from the candidate window of the current frame are obtained. The correspondence between target and candidate points is obtained via solving the proposed l(1) minimization problem. In order to prune the noisy matches, a robust matching criterion is proposed, where only the reliable candidate points that mutually match with target and candidate dictionary elements are considered for tracking. The object is localized by measuring the displacement of these interest points. The reliable candidate patches are used for updating the target dictionary. The performance and accuracy of the proposed tracker is benchmarked with several complex video sequences. The tracker is found to be considerably fast as compared to the reported state of the art trackers. The proposed tracker is further evaluated for various local patch sizes, number of interest points and regularization parameters. The performance of the tracker for various challenges including illumination change, occlusion, and background clutter has been quantified with a benchmark dataset containing 50 videos. (C) 2014 Elsevier B.V. All rights reserved

MGNREGA for environmental service enhancement and vulnerability reduction: rapid appraisal in Chitradurga district, Karnataka

The activities undertaken under the Mahatma Gandhi National Rural Employment Guarantee Act in Chitradurga district, Karnataka, were assessed for their potential to enhance and provide environmental services. Key programmes implemented in 20 villages during 2009 were studied using rapid scientific assessment methods. An indicator approach was adopted to analyse environmental services such as water for irrigation and improvement in soil quality. The status of environmental services before and after implementation of the activities was examined and vulnerability indices were constructed and compared. The activities were found to have reduced the vulnerability of agricultural production, water resources and livelihoods to uncertain rainfall, water scarcity and poor soil fertility

Cell-Derived Vesicles as TRPC1 Channel Delivery Systems for the Recovery of Cellular Respiratory and Proliferative Capacities

Pulsed electromagnetic fields (PEMFs) are capable of specifically activating a TRPC1‐mitochondrial axis underlying cell expansion and mitohormetic survival adaptations. This study characterizes cell‐derived vesicles (CDVs) generated from C2C12 murine myoblasts and shows that they are equipped with the sufficient molecular machinery to confer mitochondrial respiratory capacity and associated proliferative responses upon their fusion with recipient cells. CDVs derived from wild type C2C12 myoblasts include the cation‐permeable transient receptor potential (TRP) channels, TRPC1 and TRPA1, and directly respond to PEMF exposure with TRPC1‐mediated calcium entry. By contrast, CDVs derived from C2C12 muscle cells in which TRPC1 has been genetically knocked‐down using CRISPR/Cas9 genome editing, do not. Wild type C2C12‐derived CDVs are also capable of restoring PEMF‐induced proliferative and mitochondrial activation in two C2C12‐derived TRPC1 knockdown clonal cell lines in accordance to their endogenous degree of TRPC1 suppression. C2C12 wild type CDVs respond to menthol with calcium entry and accumulation, likewise verifying TRPA1 functional gating and further corroborating compartmental integrity. Proteomic and lipidomic analyses confirm the surface membrane origin of the CDVs providing an initial indication of the minimal cellular machinery required to recover mitochondrial function. CDVs hence possess the potential of restoring respiratory and proliferative capacities to senescent cells and tissues.ISSN:2366-747