Updates of WRW_R effects on CP angles determination in B decays

The recently observed CP violation in B decay and $B$-\ovar{B} mixing data put constraints on the mass of $W_R$ and the parameters of the right-handed current quark mixing matrix $V^R$ in $SU(2)_L \times SU(2)_R\times U(1)$ gauge model. It is shown that the allowed region of parameters are severely restricted for light $W_R$ with mass on the order of 1 TeV. There exist sets of parameters which can accommodate large CP violation as measured by Belle, $\sin2\phi_1|_{exp}\simeq 1$, for $M_{W_R}=1 \sim 10$ TeV.Comment: 11pages, 19 figures, LaTeX2

Stent-grafting for a thoracic aortic aneurysm ruptured into the right pleural cavity

AbstractEur J Vasc Endovasc Surg 25, 185–187 (2003

Study of B→D∗∗πB\to D^{**} \pi decays

We investigate the production of the novel $P$-wave mesons $D^{*}_{0}$ and $D^{\prime}_{1} (D_{1})$, identified as $J^{P}=0^+$ and $1^+$, in heavy $B$ meson decays, respectively. With the heavy quark limit, we give our modelling wave functions for the scalar meson $D^{*}_{0}$. Based on the assumptions of color transparency and factorization theorem, we estimate the branching ratios of $B\to D^{*}_{0} \pi$ decays in terms of the obtained wave functions. Some remarks on $D^{(\prime)}_{1}$ productions are also presented.Comment: 16 pages, 2 figures, Revtex4, to be published in Phys. Rev.

Evolution of the streamwise vortices in a coaxial jet controlled with micro flap-actuators

A coaxial jet was actively controlled by a MEMS-fabricated micro flap actuator nozzle. The effect of different control modes on secondary azimuthal instabilities and the evolution of streamwise vortices were investigated by applying stereoscopic PIV to the cross-stream plane of the jet. Forcing with non-symmetric modes, in particular the least-stable helical mode, accelerates the evolution of the streamwise vortices through the enhancement of azimuthal instabilities. Although forcing is applied to the outer shear layer of the outer jet, the control effect is most pronounced in the inner shear layer of the inner jet. Unlike in the natural jet, streamwise vortices appear in the inner shear layer of the controlled jet. For forcing with the fundamental axisymmetric mode, a Strouhal number of the order of unity maximise the azimuthal instabilities and hence the counts of the streamwise vortices. The present result is in accordance with our previous experimental findings in the longitudinal plane, where the evolution of the primary vortices and mixing between the inner and the outer jets were examined through 2D-PIV and PLI

Study of color suppressed modes B0→Dˉ(∗)0η(′)B^0 \to \bar D^{(*)0} \eta^{(\prime)}

The color suppressed modes $B^0 \to \bar D^{(*)0} \eta^{(\prime)}$ are analyzed in perturbative QCD approach. We find that the dominant contribution is from the non-factorizable diagrams. The branching ratios calculated in our approach for $B^0 \to \bar D^{(*)0} \eta$ agree with current experiments. By neglecting the gluonic contribution, we predict the branching ratios of $B^0 \to \bar D^{(*)0} \eta'$ are at the comparable size of $B^0 \to \bar D^{(*)0} \pi^0$, but smaller than that of $B^0 \to \bar D^{(*)0} \eta$.Comment: revtex, 5 pages, axodraw.st

Evidence for two-quark content of f0(980)f_{0}(980) in exclusive b→cb\to c decays

Inspired by a large decay branching ratio (BR) of $B^{+}\to f_{0}(980)K^{+}$ measured by Belle recently, we propose that a significant evidence of the component of $n\bar{n}=(u\bar{u}+d\bar{d})/\sqrt{2}$ in $f_{0}(980)$ could be demonstrated in exclusive $b\to c$ decays by the observation of $f_{0}(980)$ in the final states $\bar{B}\to D^{0(*)} \pi^{+} \pi^{-}(KK)$ and $\bar{B}\to J/\Psi \pi^{+} \pi^{-}(KK)$. We predict the BRs of $\bar{B}\to D^{0(*)} (J/\Psi) f_{0}(980)$ to be ${\cal {O}}(10^{-4})$ (${\cal {O}}(10^{-5})$) while the unknown wave functions of $D^{(*)0}$ ($J/\Psi$) are chosen to fit the observed decays of $\bar{B}\to D^{(*)0} \pi^{0} (J/\Psi K^{0(*)})$.Comment: 4 pages, 2 figures, Revtex4, version to appear in PR

Nonfactorizable contributions to B→D(∗)MB \to D^{(*)} M decays

While the factorization assumption works well for many two-body nonleptonic $B$ meson decay modes, the recent measurement of $\bar B\to D^{(*)0}M^0$ with $M=\pi$, $\rho$ and $\omega$ shows large deviation from this assumption. We analyze the $B\to D^{(*)}M$ decays in the perturbative QCD approach based on $k_T$ factorization theorem, in which both factorizable and nonfactorizable contributions can be calculated in the same framework. Our predictions for the Bauer-Stech-Wirbel parameters, $|a_2/a_1|= 0.43\pm 0.04$ and $Arg(a_2/a_1)\sim -42^\circ$ and $|a_2/a_1|= 0.47\pm 0.05$ and $Arg(a_2/a_1)\sim -41^\circ$, are consistent with the observed $B\to D\pi$ and $B\to D^*\pi$ branching ratios, respectively. It is found that the large magnitude $|a_2|$ and the large relative phase between $a_2$ and $a_1$ come from color-suppressed nonfactorizable amplitudes. Our predictions for the ${\bar B}^0\to D^{(*)0}\rho^0$, $D^{(*)0}\omega$ branching ratios can be confronted with future experimental data.Comment: 25 pages with Latex, axodraw.sty, 6 figures and 5 tables, Version published in PRD, Added new section 5 and reference

Pre-clinical characterization of GMP grade CCL21-gene modified dendritic cells for application in a phase I trial in Non-Small Cell Lung Cancer

<p>Abstract</p> <p>Background</p> <p>Our previous studies have demonstrated that transduction of human dendritic cells (DC) with adenovirus encoding secondary lymphoid chemokine, CCL21, led to secretion of biologically active CCL21 without altering DC phenotype or viability. In addition, intratumoral injections of CCL21-transduced DC into established murine lung tumors resulted in complete regression and protective anti-tumor immunity. These results have provided the rationale to generate a clinical grade adenoviral vector encoding CCL-21 for <it>ex vivo </it>transduction of human DC in order to assess intratumoral administration in late stage human lung cancer.</p> <p>Methods</p> <p>In the current study, human monocyte-derived DC were differentiated by exposure to GM-CSF and IL-4 from cryopreserved mononuclear cells obtained from healthy volunteers. Transduction with clinical grade adenoviral vector encoding CCL21 (1167 viral particles per cell) resulted in secretion of CCL21 protein.</p> <p>Results</p> <p>CCL21 protein production from transduced DC was detected in supernatants (24–72 hours, 3.5–6.7 ng/4–5 × 10⁶cells). DC transduced with the clinical grade adenoviral vector were > 88% viable (n = 16), conserved their phenotype and maintained integral biological activities including dextran uptake, production of immunostimulatory cytokines/chemokines and antigen presentation. Furthermore, supernatant from CCL21-DC induced the chemotaxis of T2 cells <it>in vitro</it>.</p> <p>Conclusion</p> <p>Viable and biologically active clinical grade CCL21 gene-modified DC can be generated from cryopreserved PBMC.</p

Moderate Supersymmetric CP Violation

It is well known that supersymmetry (SUSY) gives neutron and electron electric dipole moments ($d_n$ and $d_e$) which are too large by about $10^{3}$. If we assume a SUSY model cannot contain fine-tunings or large mass scales, then one must require that the SUSY breaking mechanism give real soft breaking parameters, in which case the minimal SUSY model has no $CP$ violation other than from the CKM matrix (besides possible strong $CP$ violating effects). We show that in non-minimal SUSY models, a moderate amount of $CP$ violation can be induced through one loop corrections to the scalar potential, giving an effective phase of order $10^{-3}$, and thus implying $d_n$ and $d_e$ can be near their current experimental bounds $naturally$. This moderate amount of SUSY $CP$ violation could also prove important for models of electroweak baryogenesis. We illustrate our results with a specific model.Comment: 19pp plain LATEX, 1 fig (by EMAIL request), TRI-PP-93-86. (Some clarifying comments about renormalizability added--version to appear in Phys. Rev. D