30 research outputs found
Pathophysiology of parkinsonism due to hydrocephalus
No full textWe report a patient with hydrocephalus who developed levodopa responsive parkinsonism and severe bradyphrenia associated with shunt malfunction and revision. Magnetic resonance imaging revealed periaqueductal edema involving medial substantia nigra. [18F]dopa positron emission tomography demonstrated reduced uptake in the caudate and putamen with relative sparing of the posterior putamen. Hydrocephalus associated with shunt malfunction can cause a distinct parkinsonian syndrome with greater dysfunction of projections from the medial substantia nigra to anterior striatum than in idiopathic Parkinson\u27s disease
3-(Trifluoromethyl)-3-(m-isothiocyanophenyl)diazirine: Synthesis and chemical characterization of a heterobifunctional carbene-generating crosslinking reagent
No full textVinylstannylated alkylating agents as prosthetic groups for radioiodination of small molecules: design, synthesis, and application to iodoallyl analogs of spiperone and diprenorphine
No full textCentral benzodiazepine receptor imaging and quantitation with single photon emission computerised tomography: SPECT
No full textPreclinical Evaluation of Radioiodinated Quinoxaline Derivative as a Possible Brain Imaging Agent
No full textSynthesis and Structure-Activity Relationship of the First Nonpeptidergic Inverse Agonists for the Human Cytomegalovirus Chemokine Receptor US28
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