76 research outputs found
Complex Visibilities of Cosmic Microwave Background Anisotropies
We study the complex visibilities of the cosmic microwave background
anisotropies that are observables in interferometric observations of the cosmic
microwave background, using the multipole expansion methods commonly adopted in
analyzing single-dish experiments. This allows us to recover the properties of
the visibilities that is obscured in the flat-sky approximation. Discussions of
the window function, multipole resolution, instrumental noise, pixelization,
and polarization are given.Comment: 22 pages, 1 figure include
Between-centre differences and treatment effects in randomized controlled trials: A case study in traumatic brain injury
BACKGROUND: In Traumatic Brain Injury (TBI), large between-centre differences in outcome exist and many clinicians believe that such differences influence estimation of the treatment effect in randomized controlled trial (RCTs). The aim of this study was to assess the influence of between-centre differences in outcome on the estimated treatment effect in a large RCT in TBI. METHODS: We used data from the MRC CRASH trial on the efficacy of corticosteroid infusion in patients with TBI. We analyzed the effect of the treatment on 14 day mortality with fixed effect logistic regression. Next we used random effects logistic regression with a random intercept to estimate the treatment effect taking into account between-centre differences in outcome. Between-centre differences in outcome were expressed with a 95% range of odds ratios (OR) for centres compared to the average, based on the variance of the random effects (tau2). A random effects logistic regression model with random slopes was used to allow the treatment effect to vary by centre. The variation in treatment effect between the centres was expressed in a 95% range of the estimated treatment ORs. RESULTS: In 9978 patients from 237 centres, 14-day mortality was 19.5%. Mortality was higher in the treatment group (OR = 1.22, p = 0.00010). Using a random effects model showed large between-centre differences in outcome (95% range of centre effects: 0.27- 3.71), but did not substantially change the estimated treatment effect (OR = 1.24, p = 0.00003). There was limited, although statistically significant, between-centre variation in the treatment effect (OR = 1.22, 95% treatment OR range: 1.17-1.26). CONCLUSION: Large between-centre differences in outcome do not necessarily affect the estimated treatment effect in RCTs, in contrast to current beliefs in the clinical area of TBI
Status of QUBIC, the Q&U Bolometer for Cosmology
The Q&U Bolometric Interferometer for Cosmology (QUBIC) is a novel kind of
polarimeter optimized for the measurement of the B-mode polarization of the
Cosmic Microwave Back-ground (CMB), which is one of the major challenges of
observational cosmology. The signal is expected to be of the order of a few
tens of nK, prone to instrumental systematic effects and polluted by various
astrophysical foregrounds which can only be controlled through multichroic
observations. QUBIC is designed to address these observational issues with a
novel approach that combines the advantages of interferometry in terms of
control of instrumental systematics with those of bolometric detectors in terms
of wide-band, background-limited sensitivity.Comment: Contribution to the 2022 Cosmology session of the 33rd Rencontres de
Blois. arXiv admin note: substantial text overlap with arXiv:2203.0894
QUBIC instrument for CMB polarization measurements
Measurements of cosmic microwave background (CMB) polarization may reveal the presence of a background of gravitational waves produced during cosmic inflation, providing thus a test of inflationary models. The Q&U Bolometric Interferometer for Cosmology (QUBIC) is an experiment designed to measure the CMB polarization. It is based on the novel concept of bolometric interferometry, which combines the sensitivity of bolometric detectors with the properties of beam synthesis and control of calibration offered by interferometers. To modulate and extract the input polarized signal of the CMB, QUBIC exploits Stokes polarimetry based on a rotating half-wave plate (HWP). In this work, we illustrate the design of the QUBIC instrument, focusing on the polarization modulation system, and we present preliminary results of beam calibrations and the performance of the HWP rotator at 300 K
QUBIC VI: cryogenic half wave plate rotator, design and performances
Inflation Gravity Waves B-Modes polarization detection is the ultimate goal
of modern large angular scale cosmic microwave background (CMB) experiments
around the world. A big effort is undergoing with the deployment of many
ground-based, balloon-borne and satellite experiments using different methods
to separate this faint polarized component from the incoming radiation. One of
the largely used technique is the Stokes Polarimetry that uses a rotating
half-wave plate (HWP) and a linear polarizer to separate and modulate the
polarization components with low residual cross-polarization. This paper
describes the QUBIC Stokes Polarimeter highlighting its design features and its
performances. A common systematic with these devices is the generation of large
spurious signals synchronous with the rotation and proportional to the
emissivity of the optical elements. A key feature of the QUBIC Stokes
Polarimeter is to operate at cryogenic temperature in order to minimize this
unwanted component. Moving efficiently this large optical element at low
temperature constitutes a big engineering challenge in order to reduce friction
power dissipation. Big attention has been given during the designing phase to
minimize the differential thermal contractions between parts. The rotation is
driven by a stepper motor placed outside the cryostat to avoid thermal load
dissipation at cryogenic temperature. The tests and the results presented in
this work show that the QUBIC polarimeter can easily achieve a precision below
0.1{\deg} in positioning simply using the stepper motor precision and the
optical absolute encoder. The rotation induces only few mK of extra power load
on the second cryogenic stage (~ 8 K).Comment: Part of a series of 8 papers on QUBIC to be submitted to a special
issue of JCA
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