Methemoglobinemia developing after circumcision and its treatment

Methemoglobinemi, özellikle lidokain ve prilokain kullanılan durumlarda gözlenen, klinik olarak ağır seyreden bir durumdur. Prilokain, infiltrasyon anestezisinde kısa etki profilinden dolayı en sık kullanılan amid tipi lokal anesteziklerden biri olup, ayrıca edinsel methemoglobinemiye en sık neden olan ajanlardan biridir.Olgumuzda 2 ay 10 günlük çocuğa dorsal penil blokaj ile yapılan sünnet sonucunda görülen methemoglobineminin yönetiminden sunacağız.Methemoglobinemia, especially observed in cases used lidocaine and prilocaine, is a condition characterized severe clinical. Prilocaine, is one of the most commonly used amide-type local anesthetics in infiltration anesthesia, is also one of the most common causative agent of acquired methemoglobinemia.In our case, 2 months 10 days of the child, we will provide management of methemoglobinemia as a results of circumcision with dorsal penile block

Towards composite suspension control arm: conceptual design, structural analysis, laminate optimization, manufacturing, and experimental testing

The automotive industry needs composite materials to decrease the weight of new-generation vehicles whilst increasing their strength. In this study, one of the critical (load bearing) components of automobiles, i.e., the suspension control arm made of steel, is fully redesigned for its suitable manufacturing using composite materials. To this end, innovative mechanical simulation methods are developed and coupled to perform the design, analysis, and optimization of the automotive suspension control arm. The main design/optimization criteria are set to reduce no less than 75% weight of the metal control arm and increase its safety by at least 60% by using composite materials and a new geometry suitable for mass production. To predict the deformation-stress state of the control arm, a four-node quadrilateral shell element is implemented based on the kinematics of refined zigzag theory (RZT). Once verified numerically, the computer implementation of the RZT is combined with the optimization algorithm to achieve the optimum laminate stacking sequence of the control arm. Accordingly, prototypes of the composite control arms with optimum lamination plans are manufactured and then experimentally tested under the loading and constraint conditions defined at the conceptual design stage. The numerical and full-scale experimental results are compared, and the RZT models are comprehensively validated. Hence, the advantages of the overarching design-analysis-optimization strategy presented herein are revealed for redesigning and manufacturing automobile parts from composite materials