19 research outputs found

    Diagnosis of peripartum depression disorder:A state-of-the-art approach from the COST Action Riseup-PPD

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    Background: Peripartum depression (PPD) is a major depression disorder (MDD) episode with onset during pregnancy or within four weeks after childbirth, as defined in DSM-5. However, research suggests that PPD may be a distinct diagnosis. The goal of this study was to summarize the similarities and differences between PPD and MDD by synthesizing the current research on PPD diagnosis concerning different clinical features and give directions for improving diagnosis of PPD in clinical practice. Methods: To lay the groundwork for this narrative review, several databases were searched using general search phrases on PPD and its components of clinical diagnosis. Results: When compared to MDD, peripartum depression exhibits several distinct characteristics. PPD manifests with a variety of symptoms, i.e., more anxiety, psychomotor symptoms, obsessive thoughts, impaired concentration, fatigue and loss of energy, but less sad mood and suicidal ideation, compared to MDD. Although PPD and MDD prevalence rates are comparable, there are greater cross-cultural variances for PPD. Additionally, PPD has some distinct risk factors and mechanisms such as distinct ovarian tissue expression, premenstrual syndrome, unintended pregnancy, and obstetric complications. Conclusion: There is a need for more in-depth research comparing MDD with depression during pregnancy and the entire postpartum year. The diagnostic criteria should be modified, particularly with (i) addition of specific symptoms (i.e., anxiety), (ii) onset specifier extending to the first year following childbirth, (iii) and change the peripartum onset specifier to either “pregnancy onset” or “postpartum onset”. Diagnostic criteria for PPD are further discussed.</p

    Diagnosis of peripartum depression disorder:A state-of-the-art approach from the COST Action Riseup-PPD

    Get PDF
    Background: Peripartum depression (PPD) is a major depression disorder (MDD) episode with onset during pregnancy or within four weeks after childbirth, as defined in DSM-5. However, research suggests that PPD may be a distinct diagnosis. The goal of this study was to summarize the similarities and differences between PPD and MDD by synthesizing the current research on PPD diagnosis concerning different clinical features and give directions for improving diagnosis of PPD in clinical practice. Methods: To lay the groundwork for this narrative review, several databases were searched using general search phrases on PPD and its components of clinical diagnosis. Results: When compared to MDD, peripartum depression exhibits several distinct characteristics. PPD manifests with a variety of symptoms, i.e., more anxiety, psychomotor symptoms, obsessive thoughts, impaired concentration, fatigue and loss of energy, but less sad mood and suicidal ideation, compared to MDD. Although PPD and MDD prevalence rates are comparable, there are greater cross-cultural variances for PPD. Additionally, PPD has some distinct risk factors and mechanisms such as distinct ovarian tissue expression, premenstrual syndrome, unintended pregnancy, and obstetric complications. Conclusion: There is a need for more in-depth research comparing MDD with depression during pregnancy and the entire postpartum year. The diagnostic criteria should be modified, particularly with (i) addition of specific symptoms (i.e., anxiety), (ii) onset specifier extending to the first year following childbirth, (iii) and change the peripartum onset specifier to either “pregnancy onset” or “postpartum onset”. Diagnostic criteria for PPD are further discussed.</p

    Pre-operative grip force as clinical predictor for weakness after transversal carpal ligament release

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    Pre-operative grip force as clinical predictor for weakness after transversal carpal ligament release

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    Towards composite suspension control arm: conceptual design, structural analysis, laminate optimization, manufacturing, and experimental testing

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    The automotive industry needs composite materials to decrease the weight of new-generation vehicles whilst increasing their strength. In this study, one of the critical (load bearing) components of automobiles, i.e., the suspension control arm made of steel, is fully redesigned for its suitable manufacturing using composite materials. To this end, innovative mechanical simulation methods are developed and coupled to perform the design, analysis, and optimization of the automotive suspension control arm. The main design/optimization criteria are set to reduce no less than 75% weight of the metal control arm and increase its safety by at least 60% by using composite materials and a new geometry suitable for mass production. To predict the deformation-stress state of the control arm, a four-node quadrilateral shell element is implemented based on the kinematics of refined zigzag theory (RZT). Once verified numerically, the computer implementation of the RZT is combined with the optimization algorithm to achieve the optimum laminate stacking sequence of the control arm. Accordingly, prototypes of the composite control arms with optimum lamination plans are manufactured and then experimentally tested under the loading and constraint conditions defined at the conceptual design stage. The numerical and full-scale experimental results are compared, and the RZT models are comprehensively validated. Hence, the advantages of the overarching design-analysis-optimization strategy presented herein are revealed for redesigning and manufacturing automobile parts from composite materials
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