Role of clobetasol propionate 0.025% topical therapy in various dermatoses

The anti-inflammatory and vasoconstrictive properties of topical corticosteroids (TCs) contribute in providing therapeutic benefits in several skin conditions, including atopic eczema, localized vitiligo, psoriasis, and chronic hand eczema. Clobetasol propionate (CP) is the most common topical agent used for psoriasis management and demonstrates an efficacy superior to other TCs. A new CP 0.025% cream formulation has demonstrated hypoallergenic effects due to the absence of known contact allergens, such as propylene glycol, short-chain alcohols, and sorbitol-based emulsifiers. Lower CP serum levels and less hypothalamic–pituitary–adrenal axis suppression with CP 0.025% cream formulation than with CP 0.05% ensure better safety. The present case series discusses the clinical experience of using CP 0.025% cream in various dermatological conditions

IGBT Based Four Quadrant Chopper Drive Closed Loop Control for DC

These manuscripts present a closed-loop IGBT-based fourquadrant chopper drive system for DC motors. This paper intends to improve DC motor control’s accuracy, effectiveness, and adaptability in a variety of applications. In this paper, we build and put into practice a closed-loop control system that incorporates IGBT in order to manage the speed and torque of DC motors in both directions. A feedback system with sensors for measuring motor speed and current is used in the closed-loop control scheme to ensure perfect regulation of motor parameters. The IGBT-based chopper drive architecture allows for smooth switching between forward and reverse motor operation as well as dynamic braking, making it appropriate for applications requiring four-quadrant operation. The main benefits of our suggested system are greater motor protection through fault detection and quick responses to external disturbances, improved speed and torque management, and lower energy consumption. We show experimental data that demonstrate our design’s capacity to maintain stable motor functioning across a variety of operating situations, validating its usefulness in real-world applications. The presented system simulation result is verified in MATLAB/Simulink software. The demonstrated results are motor speed, torque, current and voltage