How Do Interactions Between Early Caregiving Environment and Genes Influence Health and Behavior?

Article deposited according to publisher policies: https://us.sagepub.com/en-us/nam/the-green-route-%E2%80%93-open-access-archiving-policy. Article DOI 10.1177/1099800412463602To promote optimal health and behavioral outcomes in children, nurses have long supported parents in providing the best possible care and nurturance to their offspring. A growing body of neuroscience research argues convincingly for the combined influences of genes and early caregiving on producing an individual’s unique health and behavioral phenotype. In this article, we systematically review studies that demonstrate the relationship between qualities of early caregiving and genetic propensity to health and behavioral outcomes. From an initial set of 255 articles, 24 articles met our inclusion criteria. The outcomes fall into four distinct groups: hypothalamic-pituitary-adrenal (HPA) response to stress, externalizing behavior, internalizing behavior, and disorganized attachment. In the articles, authors examined genes that code for the 5-hydroxy tryptamine (serotonin) transporter genes linked polymorphic region [5-HTTLPR] serotonin transporter promoter, D4 dopamine receptor, brain-derived neurotrophic factor, and monoamine oxidase A promoter. The reviewed studies suggest that the effect of the early rearing environment on gene expression relates mainly to HPA response to stress, whereas interactions between genes and caregiving mainly relate to behavior and attachment. Findings have implications for nurses focused on advocacy, prevention, and intervention to support the healthy development of children in families faced with adversity.Ye

Improving Access to Specialist Care for an Aging Population

Objective: The objective of the study is to examine the Champlain. BASE TM ( B uilding A ccess to S pecialists through e Consultation) eConsult service’s impact on access to care for older persons. Methods: We conducted a cross-sectional analysis of all eConsult cases submitted between April 15, 2011, and July 31, 2015, in which the patient was above the age of 65 years. Study data consisted of utilization data collected automatically by the service and responses to surveys completed by primary care providers at the conclusion of all eConsult cases. Results: A total of 1,796 cases were submitted for older persons between April 15, 2011, and July 31, 2015, accounting for 21.3% of all cases submitted during the study period. Specialists responded to cases in a median of 0.8 days. In 94% of cases, providers rated eConsult as having great or excellent value for themselves and their patients. Sixty-eight percent of eConsults did not require a face-to-face visit; only 28% of all cases resulted in a referral. Discussion: As they suffer from higher than average rates of comorbid disease and mobility issues, older persons stand to benefit from shorter wait times and better access to care, which the eConsult service can provide