36 research outputs found

    Realistic Calculation of the hep Astrophysical Factor

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    The astrophysical factor for the proton weak capture on 3He is calculated with correlated-hyperspherical-harmonics bound and continuum wave functions corresponding to a realistic Hamiltonian consisting of the Argonne v18 two-nucleon and Urbana-IX three-nucleon interactions. The nuclear weak charge and current operators have vector and axial-vector components, that include one- and many-body terms. All possible multipole transitions connecting any of the p-3He S- and P-wave channels to the 4He bound state are considered. The S-factor at a p-3He center-of-mass energy of 10 keV, close to the Gamow-peak energy, is predicted to be 10.1 10^{-20} keV b, a factor of five larger than the standard-solar-model value. The P-wave transitions are found to be important, contributing about 40 % of the calculated S-factor.Comment: 8 pages RevTex file, submitted to Phys. Rev. Let

    RhoE Deficiency Produces Postnatal Lethality, Profound Motor Deficits and Neurodevelopmental Delay in Mice

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    Rnd proteins are a subfamily of Rho GTPases involved in the control of actin cytoskeleton dynamics and other cell functions such as motility, proliferation and survival. Unlike other members of the Rho family, Rnd proteins lack GTPase activity and therefore remain constitutively active. We have recently described that RhoE/Rnd3 is expressed in the Central Nervous System and that it has a role in promoting neurite formation. Despite their possible relevance during development, the role of Rnd proteins in vivo is not known. To get insight into the in vivo function of RhoE we have generated mice lacking RhoE expression by an exon trapping cassette. RhoE null mice (RhoE gt/gt) are smaller at birth, display growth retardation and early postnatal death since only half of RhoE gt/gt mice survive beyond postnatal day (PD) 15 and 100% are dead by PD 29. RhoE gt/gt mice show an abnormal body position with profound motor impairment and impaired performance in most neurobehavioral tests. Null mutant mice are hypoactive, show an immature locomotor pattern and display a significant delay in the appearance of the hindlimb mature responses. Moreover, they perform worse than the control littermates in the wire suspension, vertical climbing and clinging, righting reflex and negative geotaxis tests. Also, RhoE ablation results in a delay of neuromuscular maturation and in a reduction in the number of spinal motor neurons. Finally, RhoE gt/gt mice lack the common peroneal nerve and, consequently, show a complete atrophy of the target muscles. This is the first model to study the in vivo functions of a member of the Rnd subfamily of proteins, revealing the important role of Rnd3/RhoE in the normal development and suggesting the possible involvement of this protein in neurological disorders

    Determination of nitrogen in atmospheric aerosols by proton activation analysis

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    Nuclear reactions induced by 7.6-MeV deuterons are used to determine total carbon in atmospheric aerosols. The {sup 12}C(d,n){sup 13}N reaction produces the radionuclide {sup 13}N, a 10.0-min positron emitter, which is detected by its 0.511-MeV annihilation radiation. The detection system is a Ge(Li) {gamma}-ray spectrometer. The method is nondestructive of the sample, permitting the sample to be studied by additional methods. Comparison of carbon found by deuteron activation analysis with that found by independent but destructive combustion methods shows a standard deviation of 10% for 15 samples analyzed over a wide range of carbon contents. The detection limit is estimated to be 0.5 {micro}g/cm{sup 2}, corresponding to a carbon concentration of 0.2% in a sample of total thickness 250 {micro}g/cm{sup 2}
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