Anisotropic optical properties of rhombohedral and tetragonal thin film BiFeO3_3 phases

The anisotropic optical properties of multiferroic BiFeO$_3$ thin films have been determined with Mueller matrix ellipsometry at room-temperature. The full dielectric tensors of tetragonal-like and rhombohedral-like BiFeO$_3$ phases epitaxially grown on LaAlO$_3$ and SrTiO$_3$ single crystal substrates, respectively, within the spectral range of 0.6 and 6.5 eV are reported. Strain-driven anisotropy changes and transition shifts are observed as well as evidence of sub-band gap many-particle excitations are found. The transition shifts, mostly to higher energies for the highly strained tetragonal-like BiFeO$_3$ phase on LaAlO$_3$, are indicative of band structure differences. Additionally, optical modelling, confirmed by piezoelectric force microscopy studies, revealed that the average polarization direction of bivariant BiFeO$_3$ on LaAlO$_3$ is not parallel to the crystallographic [001] direction but tilted by about $7^{\circ}$. Spectral weight analyses reveal phase-dependent differences underlining that theoretical calculations of optical spectra need further improvement to appropriately account for electronic and excitonic correlations to fully understand multiferroic BiFeO$_3$.Comment: 7 pages, 5 figure

Meteorologically Defined Limits to Reduction in the Variability of Outputs from a Coupled Wind Farm System in the Central US

Studies suggest that onshore wind resources in the contiguous US could readily accommodate present and anticipated future US demand for electricity. The problem with the output from a single wind farm located in any particular region is that it is variable on time scales ranging from minutes to days posing difficulties for incorporating relevant outputs into an integrated power system. The high frequency (shorter than once per day) variability of contributions from individual wind farms is determined mainly by locally generated small scale boundary layer. The low frequency variability (longer than once per day) is associated with the passage of transient waves in the atmosphere with a characteristic time scale of several days. Using 5 years of assimilated wind data, we show that the high frequency variability of wind-generated power can be significantly reduced by coupling outputs from 5 to 10 wind farms distributed uniformly over a ten state region of the Central US in this study. More than 95% of the remaining variability of the coupled system is concentrated at time scales longer than a day, allowing operators to take advantage of multi-day weather forecasts in scheduling projected contributions from wind.Engineering and Applied Science

Mechanism of Polarization Fatigue in BiFeO3: the Role of Schottky Barrier

By using piezoelectric force microscopy and scanning Kelvin probe microscopy, we have investigated the domain evolution and space charge distribution in planar BiFeO3 capacitors with different electrodes. It is observed that charge injection at the film/electrode interface leads to domain pinning and polarization fatigue in BiFeO3. Furthermore, the Schottky barrier at the interface is crucial for the charge injection process. Lowering the Schottky barrier by using low work function metals as the electrodes can also improve the fatigue property of the device, similar to what oxide electrodes can achieve

Optimal Integration of Offshore Wind Power for a Steadier, Environmentally Friendlier, Supply of Electricity in China

Demand for electricity in China is concentrated to a significant extent in its coastal provinces. Opportunities for production of electricity by on-shore wind facilities are greatest however in the north and west of the country. Using high resolution wind data derived from the GEOS-5 assimilation, this study shows that investments in off-shore wind facilities in these spatially separated regions (Bohai-Bay or BHB, Yangtze-River Delta or YRD, Pearl-River Delta or PRD) could make an important contribution to overall regional demand for electricity in coastal China. An optimization analysis indicates that hour-to-hour variability of outputs from a combined system can be minimized by investing 24% of the power capacity in BHB, 30% in YRD and 47% in PRD. The analysis suggests that about 28% of the overall off-shore wind potential could be deployed as base load power replacing coal-fired system with benefits not only in terms of reductions in CO2 emissions but also in terms of improvements in regional air quality. The interconnection of off-shore wind resources contemplated here could be facilitated by China’s 12th-five-year plan to strengthen inter-connections between regional electric-power grids.Engineering and Applied Science

Nanoscale domains in strained epitaxial BiFeO3 thin Films on LaSrAlO4 Substrate

BiFeO3 thin films with various thicknesses were grown epitaxially on (001) LaSrAlO4 single crystal substrates using pulsed laser deposition. High resolution x-ray diffraction measurements revealed that a tetragonal-like phase with c-lattice constant ~4.65 {\AA} is stabilized by a large misfit strain. Besides, a rhombohedral-like phase with c-lattice constant ~3.99 {\AA} was also detected at film thickness of ~50 nm and above to relieve large misfit strains. In-plane piezoelectric force microscopy studies showed clear signals and self-assembled nanoscale stripe domain structure for the tetragonal-like regions. These findings suggest a complex picture of nanoscale domain patterns in BiFeO3 thin films subjected to large compressive strains.Comment: 14 pages, 4 figure

Verification of a novel point-of-care HbA1c device in real world clinical practice by comparison to three high performance liquid chromatography instruments

Introduction: A real world clinical study was designed and conducted to evaluate the performance of a novel point-of-care device for determination of glycated haemoglobin A1c (HbA1c), A1C EZ 2.0, in daily clinical practice. Materials and methods: Five hundred and fourteen subjects were included in this study, and divided into three groups. HbA1c was measured by A1C EZ 2.0 and three different high performance liquid chromatography (HPLC) devices: Bio-Rad Variant II Turbo, Tosoh HLC-723 G8 and Premier Hb9210 separately. Precision of A1C EZ 2.0 was also evaluated. Results: Results obtained from A1C EZ 2.0 and all HPLC devices are correlated. Passing-Bablok regression analysis shows the equation of A1C EZ 2.0 results against the mean of HPLC devices with corresponding 95% confidence intervals (95% CI) for the intercept and slope is y = 0.10 (- 0.17 to 0.10) + 1.00 (1.00 to 1.04) x. Bland-Altman difference plot shows that the mean relative difference between A1C EZ 2.0 and Variant II Turbo, G8, Hb9210 and all HPLC results is 2.5%, 0.6%, 0.4% and 1.1%, respectively. In addition, 121 pairs of results determined by using both venous and capillary blood prove that the difference of two kinds of blood sample causes no notable variation when measured by A1C EZ 2.0. Precision study gives 2.3% and 1.9% of total coefficient of variation for normal and abnormal HbA1c sample in A1C EZ 2.0. Conclusions: HbA1c values measured by A1C EZ 2.0 were in good accordance with the results obtained with the reference HPLC devices

A study on the correlation between the prognosis of HPV infection and lesion recurrence after cervical conization

IntroductionPersistent human papillomavirus infection is an important factor in the development of cervical cancer, which is usually a long process evolving from the development of squamous intraepithelial lesions (SIL), also referred to as cervical intraepithelial neoplasia (CIN). Local treatment of advanced squamous intraepithelial lesions, also regarded as High-Grade Squamous Intraepithelial Lesion, may be effective in preventing cancer.ObjectiveTo promptly identify high-risk patients with a tendency to recurrence.MethodsWe retrospectively analyzed the clinical data of 300 patients with high-grade squamous intraepithelial lesions of the cervix admitted to the Second Affiliated Hospital of Dalian Medical University from 2019 to 2020 to investigate the relationship between recurrence of cervical lesions and postoperative regression of HPV infection, as well as other related risk factors.ResultsWe found that the HPV-negative rates were 81.81, 85.71, and 90.91% at 6, 12, and 24 months, respectively, and the average lesion recurrence rate was 8.16%, with a median time to recurrence of 14 months in patients undergoing CKC for HSIL. The risk of cervical squamous intraepithelial lesions was highest in patients with HPV16. Patients over 61 years of age had the lowest postoperative HPV-negative rate. The conversion rate was significantly lower in patients with multiple HPV genotypes than in those with single HPV infection (p < 0.05). The probability of recurrence was higher in patients with the same HPV infection genotype before and after surgery than in patients with different infection genotypes before and after surgery (p < 0.05).ConclusionCombined with the literature review, we believe that patients aged ≥50 years, with ≥3 pregnancies and births, a history of smoking, and consistent genotypes of preoperative and postoperative HPV infection in cervical conization have more HPV re-infection or persistent infection, and that these factors may be high-risk factors for lesion recurrence. For patients with possible potential high-risk factors, we need to carry out individualized follow-up and focused management, take timely and effective management measures, optimize the treatment plan, reduce the recurrence rate, prevent HSIL and cervical cancer, improve the quality of patient’s survival, and improve the prognosis