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6 research outputs found
The impact of trisulfide modification of antibodies on the properties of antibody-drug conjugates manufactured using thiol chemistry
Author
Alexandru C. Lazar
Junia Dushime
+5 more
Lintao Wang
Megan Bogalhas
Renpeng Liu
Thomas Ryll
Xuan Chen
Publication venue
'Informa UK Limited'
Publication date
Field of study
No full text
Crossref
Single Doses of Antibody Drug Conjugates (ADCs) Targeted to CD117 or CD45 Have Potent In Vivo Anti-Leukemia Activity and Survival Benefit in Patient Derived AML Models
Author
Andrew D. Gabros
Anthony E. Boitano
+16 more
Bradley R. Pearse
Charlotte F. McDonagh
Danielle Ladwig
Ganapathy N. Sarma
Hillary L. Adams
Jennifer L. Proctor
Junia Dushime
Lena Kien
Melissa Brooks
Michael P. Cooke
Qing Li
Rahul Palchaudhuri
Rajiv Panwar
Sean M. McDonough
Sharon Aslanian
Sharon L. Hyzy
Publication venue
'Elsevier BV'
Publication date
Field of study
No full text
Crossref
A Non-Genotoxic Anti-CD117 Antibody Drug Conjugate (ADC) Designed for Patient Conditioning Prior to Stem Cell Transplant and HSC-Based Gene Therapy Has a Broad Therapeutic Window across Species
Author
Anthony E. Boitano
Bradley R. Pearse
+17 more
Charlotte F. McDonagh
Ganapathy N. Sarma
Jason Neale
Jennifer L. Proctor
John C. Davis
Junia Dushime
Kellie Latimer
Lena Kien
Melissa L. Brooks
Michael P. Cooke
Nidhi Jain
Qing Li
Rahul Palchaudhuri
Rajiv Panwar
Ryan Knihtila
Sean M. McDonough
Tahirih L. Lamothe
Publication venue
'Elsevier BV'
Publication date
Field of study
No full text
Crossref
Single Doses of Antibody Drug Conjugates (ADCs) Targeted to CD117 or CD45 Have Potent In Vivo Anti-Leukemia Activity and Survival Benefit in Patient Derived AML Models
Author
Andrew D. Gabros
Anthony E. Boitano
+16 more
Bradley R. Pearse
Charlotte F. McDonagh
Danielle Ladwig
Ganapathy N. Sarma
Hillary L. Adams
Jennifer L. Proctor
Junia Dushime
Lena Kien
Melissa Brooks
Michael P. Cooke
Qing Li
Rahul Palchaudhuri
Rajiv Panwar
Sean M. McDonough
Sharon Aslanian
Sharon L. Hyzy
Publication venue
'Elsevier BV'
Publication date
Field of study
No full text
Crossref
A CD117-Amanitin Antibody Drug Conjugate (ADC) Effectively Depletes Human and Non-Human Primate Hematopoietic Stem and Progenitor Cells (HSPCs): targeted Non-Genotoxic Conditioning for Bone Marrow Transplant
Author
Anthony E. Boitano
Bradley R. Pearse
+16 more
Charlotte F McDonagh
Ganapathy N Sarma
Hillary L. Adams
Jennifer L. Proctor
Junia Dushime
Lena Kien
Melissa Brooks
Michael P. Cooke
Nidhi Jain
Pranoti Sawant
Qing Li
Rahul Palchaudhuri
Rajiv Panwar
Sean M. McDonough
Sharon L. Hyzy
Tahirih L Lamothe
Publication venue
'Elsevier BV'
Publication date
Field of study
No full text
Crossref
Non-Genotoxic Conditioning Using Amanitin Antibody-Drug Conjugates Targeting CD45 Effectively Deplete Human and Non-Human Primate Hematopoietic Stem Cells and Immune Cells
Author
Andrew D Gabros
Anjali Bhat
+21 more
Anthony E. Boitano
Brad R. Pearse
Charlotte F McDonagh
Danielle Ladwig
Ganapathy N Sarma
Geoff O Gillard
Hillary L. Adams
Jennifer L. Proctor
Junia Dushime
Lena Kien
Michael P. Cooke
Nidhi Jain
Patrick C. Falahee
Pranoti Sawant
Qing Li
Rahul Palchaudhuri
Rajiv Panwar
Sean M. McDonough
Sharon Aslanian
Sharon L. Hyzy
Tahirih L Lamothe
Publication venue
'Elsevier BV'
Publication date
Field of study
No full text
Crossref