139 research outputs found

    Critiquing Sustainable Openness in Technology-Based Education from the Perspective of Cost-Effectiveness and Accessibility

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    The over-exaggeration of technology’s role in education has dominated the landscape of research, often resulting in the negligence of other important issues. This article critiques openness in technology-based education from the perspective of sustainability, put more specifically, cost-effectiveness and accessibility, both of which have direct impact on sustainable openness. It first reviews the purpose of using technology in education advocated in strategy documents, namely using technology to break the iron triangle of access, cost, and quality, hence increasing openness in high-quality education. It contends that technology-based education cannot be sustainably open without both cost-effectiveness and accessibility. Nevertheless, sustainable openness is an under-researched theme according to the findings from a review of 3,059 primary studies conducted in this article. The article then goes on to rethink sustainable openness in the digital age, arguing that technology-based education should be cost-effective to educational institutions and students alike and cater for socio-economic diversity and disparity, among other things, to ensure sustainable openness to all. It concludes by calling for a critical approach to researching technology-based education with the aim of achieving high quality, cost-effectiveness, and accessibility at the same time and opening up education to all

    Will Artificial Intelligence Enable Open Universities to Regain their Past Glory in the 21st Century?

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    Leveraging technology to break the iron triangle of access, cost, and quality is a legacy of open universities (OUs), becoming a source of inspiration for higher education in general. Today, OUs face increasing competition from conventional universities, no longer enjoying the first-mover advantages as they did in the earlier years. Can artificial intelligence (AI) enable OUs to stay competitive in the 21st century as other technologies did in the past? This paper first reviews literature on the affordances or (potential) uses of AI for open and distance education and then examines the implications of these affordances for OUs in terms of quality, cost, and access. It concludes by arguing for a systems approach to exploring how OUs can remain open as to people and places as well as to methods and ideas by making creative and innovative uses of AI

    (E)-1-[4-(Dimethyl­amino)benzyl­idene]thio­semicarbazide

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    In the title mol­ecule, C10H14N4S, the thio­rea plane and benzene ring form a dihedral angle of 16.0 (3) Å. In the crystal structure, inter­molecular N—H⋯S hydrogen bonds link the mol­ecules into ribbons extended in the [100] direction; these incorporate inversion dimers

    EXPLORING AN INTEGRATED APPROACH TO WEB-BASED COURSE ASSESSMENT

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    Web-based course assessment is a new thing at China's Open University – China Radio and Television Universities (China RTVUs). This article reports an innovative pilot study in this research area. The experimental course for integrated web-based assessment in this study is Advanced English Writing, which is a compulsory course in the B.A. English programme at China Central Radio and Television University (CCRTVU). The study started in March 2005 and it is still in progress at the moment. This article first describes the webbased assessment design of the course and the implementation procedures. Then it moves on to report some initial feedback from the student participants on the pilot study. The article ends with a tentative plan for further actions based on the current study

    Advances on mechanisms of regulated cell death in neurotoxicity of aluminum

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    Aluminum is a light metal which is rich in the earth's crust and widely used. Recently, the adverse health effects of environmental and occupational aluminum exposure on human have attracted more and more attention. Aluminum exposure has toxic effects on the central nervous system and is believed to be closely related to the development and progression of Alzheimer's disease. The neurotoxic mechanism of aluminum is complex, especially the role of regulated cell death (RCD) in aluminum-induced neuronal death remains to be further studied. RCD refers to all modes of cell death regulated by multiple intracellular signal transduction pathways under physiological and pathological conditions, including apoptosis, necroptosis, autophagy, pyroptosis, and ferroptosis. This review summarized the morphological characteristics and mechanisms of each RCD mode in the process of aluminum-induced neuronal death, and discussed the relationship and transformation between different RCD modes, providing a new scientific basis for future studies on the treatment and intervention of neurotoxicity induced by aluminum exposure

    Institutional Measures for Supporting OER in Higher Education: An International Case-Based Study

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    Open Educational Resources (OER) in higher education cannot be put into practice without considering institutional contexts, which differ not only globally but also within the same country. Each institutional context provides educators with opportunities or limitations where Open Educational Practices (OEP) and OER for teaching and learning are involved. As part of a broader research project, and as a follow-up to national perspectives, an international comparison was conducted, based on institutional cases of nine different higher education systems (Australia, Canada, China, Germany, Japan, South Africa, South Korea, Spain, Turkey). Aspects regarding the availability of infrastructure and institutional policies for OER, as well as the existence of measures directed at OER quality assurance and at the promotion of the development and use of OER were covered. The resulting theoretical contribution sheds light on an international comparative view of OER and points towards country-specific trends, as well as differences among institutions. These aspects could provide an impetus for the development of institutional guidelines and measures. In line with international literature on the topic, recommendations are derived to promote/ enhance the use of OER in teaching and learning in higher education at the institutional level.This article is part of the meso level report of work package 11 of the project “Digital educational architectures: Open learning resources in distributed learning infrastructures – EduArc” funded by the German Federal Ministry of Education and Research (grant #16DHB2129)

    PI3K-Akt-mTOR axis sustains rotavirus infection via the 4E-BP1 mediated autophagy pathway and represents an antiviral target

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    Rotavirus infection is a major cause of severe dehydrating diarrhea in infants younger than 5 y old and in particular cases of immunocompromised patients irrespective to the age of the patients. Although vaccines have been developed, an
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