4,417 research outputs found
Measuring properties of a Heavy Higgs boson in the decay
In many extensions of the standard model, there exist a few extra Higgs
bosons. Suppose a heavy neutral Higgs boson H is discovered at the LHC, one
could then investigate CP and CPT~ properties of its couplings to a pair of
bosons through . We use the helicity-amplitude method to
write down the most general form for the angular distributions of the four
final-state leptons, which can cover the case of CP-even, -odd, and -mixed
state for the Higgs boson. We figure out there are 9 types of angular
observables and all the couplings to bosons can be fully determined by
exploiting them. A Higgs-boson mass of 260 GeV below the threshold is
illustrated with full details. With a total of events of , one can determine the couplings up to 12-20\% uncertainties.Comment: 23 pages, 4 figures, 3 tables, to appear in JHE
High glucose induces MCP-1 expression partly via tyrosine kinase–AP-1 pathway in peritoneal mesothelial cells
High glucose induces MCP-1 expression partly via tyrosine kinase–AP-1 pathway in peritoneal mesothelial cells.BackgroundHigh glucose in peritoneal dialysis solutions has been implicated in the pathogenesis of peritoneal fibrosis in chronic ambulatory peritoneal dialysis (CAPD) patients. However, the mechanisms are not very clear. Peritoneal macrophages seem to participate in the process of peritoneal fibrosis and monocyte chemoattractant protein-1 (MCP-1) plays a key role in the recruitment of monocytes toward the peritoneal cavity. However, little is known about the effect of high glucose on MCP-1 expression and its signal transduction pathway in human peritoneal mesothelial cells.MethodsMesothelial cells were cultured with glucose (5 to 100 mmol/L) or mannitol chronically for up to seven days. MCP-1 expression of mRNA and protein was measured by Northern blot analysis and enzyme-linked immunosorbent assay (ELISA). Chemotactic activity of high-glucose–conditioned culture supernatant was measured by chemotactic assay. To examine the roles of the transcription factors activator protein-1 (AP-1) and nuclear factor-κB (NF-κB), electrophoretic mobility shift assay (EMSA) was performed.ResultsGlucose induced MCP-1 mRNA expression in a time- and dose-dependent manner. MCP-1 protein in cell culture supernant was also increased. Equivalent concentrations of mannitol had no significant effect. High-glucose–conditioned supernatant possessed an increased chemotactic activity for monocytes, which was neutralized by anti–MCP-1 antibody. EMSA revealed that glucose increased the AP-1 binding activity in a time- and dose-dependent manner, but not NF-κB. Curcumin, an inhibitor of AP-1, dose-dependently suppressed the induction of MCP-1 mRNA by high glucose. Tyrosine kinase inhibitors such as genistein (12.5 to 50 μmol/L) and herbimycin A (0.1 to 1 μmol/L) inhibited the high-glucose–induced MCP-1 mRNA expression in a dose-dependent manner, and also suppressed the high-glucose–induced AP-1 binding activity.ConclusionsHigh glucose induced mesothelial MCP-1 expression partly via the tyrosine kinase-AP-1 pathway
Functional Requirements to Support Traffic Organization Service
In the era of e-Navigation, the future VTS is anticipated to play an important role on the enhancement of maritime safety and the efficiency of maritime transport as a key stakeholder of e-Navigation. The VTS services need the advanced Traffic Organization Service(TOS). In this paper, the VTS functions for TOS is revisited from the reports of IMO e-Navigation Correspondence Group and IALA VTS Committee. In Korea, the research activities to enhance the existing VTS functions have been conducted. In terms of TOS, some VTS functions have been developed. In conclusion, all the past traffic data and real-time ship data are required to provide the advanced TOS. For this, the advanced functions to support TOS should be implemented on VTS console
Higgs-boson-pair production from gluon fusion at the HL-LHC and HL-100 TeV hadron collider
We perform the most up-to-date comprehensive signal-background analysis for
Higgs-pair production in channel at the HL-LHC
and HL-100 TeV hadron collider, with the goal of probing the self-coupling
of the Higgs boson. We simulate all the standard-model signal
and background processes with the simulation tools almost as sophisticated as
what experimentalists are using. We find that even for the most promising
channel at the HL-LHC with a luminosity of 3000
fb, the significance is still not high enough to establish the Higgs
self-coupling at the standard model (SM) value. Instead, we can only constrain
the self-coupling to at confidence level
after considering the uncertainties associated with the top-Yukawa coupling and
the estimation of backgrounds. Here we also extend the study to the HL-100 TeV
hadron collider. With a luminosity of 3 ab, we find there exists a bulk
region of 2.6 \lsim \lambda_{3H} \lsim 4.8 in which one cannot pin down the
trilinear coupling. Otherwise one can measure the coupling with a high
precision. At the SM value, for example, we show that the coupling can be
measured with about 20 \% accuracy. While assuming 30 ab, the bulk
region reduces to 3.1 \lsim \lambda_{3H} \lsim 4.3 and the trilinear coupling
can be measured with about 7 \% accuracy at the SM value. With all the
simulated background events and results, our study can be useful to probe the
Higgs potential of various models with extended Higgs sector, such as
two-Higgs-doublet model, MSSM, etc.Comment: 35 pages, 21 figures, 15 tables; New section V. FURTHER IMPROVEMENTS
ENVISAGED added, Tables VI and XII updated, references added; New Appendix C
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Sink-Independent Model in Wireless Sensor Networks
Wireless sensor networks generally support users that send queries and receive data via the sinks. The user and the sinks are mostly connected to each other by infrastructure networks. The users, however, should receive the data from the sinks through multi-hop communications between disseminating sensor nodes if such users move into the sensor networks without infrastructure networks. To support mobile users, previous work has studied various user mobility models. Nevertheless, such approaches are not compatible with the existing routing algorithms, and it is difficult for the mobile users to gather data efficiently due to their mobility. To improve the shortcomings, we propose a view of mobility for wireless sensor networks and propose a model to support a user mobility that is independent of sinks
Linking Authentic Leadership With Employee Initiative Behavior and Task Performance: The Mediating Role of Emotional Sharing and Communication Satisfaction
Our study aims to explore the process through which authentic leadership leads to employees’ initiative behavior and task performance. In particular, we focused on the mediating roles of emotional sharing and communication satisfaction. Based on data collected from 242 employee-supervisor dyads, we found that authentic leadership was significantly related to emotional sharing, which was sequentially significantly related to communication satisfaction. Communication satisfaction was significantly associated with initiative behavior and task performance. In addition, emotional sharing and communication satisfaction played significant mediating roles not only in the relationship between authentic leadership and initiative behavior, but also in the relationship between authentic leadership and task performance. The limitations and implications for future research and practice are discussed
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