1,510 research outputs found
Effective promotions through social media: A case of Major League Baseball teams
This study examined if the impacts of Facebook promotions on fan engagement were moderated by team performance in the Major League Baseball. Two teams showing the opposite results in the 2015 seasons were selected. Likes, Shares, and Comments were measured as indicators of fan engagement. All posts were categorised in the five promotion types. A two-way MANOVA was carried out to see if there were any differences in Facebook Likes, Shares, and Comments for differing promotion types and team performance. The results revealed that there were statistically significant interaction effects between promotion types and team performance on Likes and Shares. For player/personnel promotion and team information, the numbers of Likes and Shares were significantly higher than the other promotion types for both teams. For Likes and Shares by the two significant promotion types, Royals had significantly higher mean scores than did Phillies
Monitoring of multi-frequency polarization of gamma-ray bright AGNs
We started two observing programs with the Korean VLBI Network (KVN)
monitoring changes in the flux density and polarization of relativistic jets in
gamma-ray bright AGNs simultaneously at 22, 43, 86, 129 GHz. One is a
single-dish weekly-observing program in dual polarization with KVN 21-m
diameter radio telescopes beginning in 2011 May. The other is a VLBI
monthly-observing program with the three-element VLBI network at an angular
resolution range of 1.0--9.2 mas beginning in 2012 December. The monitoring
observations aim to study correlation of variability in gamma-ray with that in
radio flux density and polarization of relativistic jets when they flare up.
These observations enable us to study the origin of the gamma-ray flares of
AGNs.Comment: 4 pages, 4 figures, Proceedings of the conference "The innermost
regions of relativistic jets and their magnetic fields", Granada, Spai
Dysfunction in Configural Face Processing in Patients With Schizophrenia
Background: Face recognition has important implications for patients with schizophrenia, who exhibit poor interpersonal and social skills. Previous reports have suggested that patients with schizophrenia have deficits in their ability to recognize faces, and because face recognition relies heavily on information about the configuration of faces, we hypothesized that patients with schizophrenia would have specific problems in processing configural information. Methods: We measured the performance of 20 patients with schizophrenia and 20 normal subjects in a face-discrimination task, using upright and inverted pairs of face photographs that differed in featural or configural information. Results: The patients with schizophrenia showed disproportionately poorer performance in discriminating configural compared with featural face sets. Conclusion: The result suggests that the face-recognition deficit in schizophrenic patients is due to specific impairments in configural processing of faces
LAPTM5 overexpression causes mitochondrial damage and apoptosis
Human lysosomal-associated protein multispanning membrane 5 (LAPTM5) was identified by an ordered differential display-polymerase chain reaction (ODD-PCR) as an up-regulated cDNA fragment during 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced differentiation of U937 cells into monocytes/macrophages. After TPA-treatment, the levels of LAPTM5 mRNA and protein increased and reached a maximum at 18-36 h. In healthy human tissues, LAPTM5 mRNA was expressed at high levels in hematopoietic cells and tissues, at low levels in the lung and fetal liver, and was not detected in other non-hematopoietic tissues. LAPTM5 mRNA was detected in immature malignant cells of myeloid lineage, such as K562, HL-60, U937, and THP-1 cells, and in unstimulated peripheral T cells, but was absent or barely detectable in lymphoid malignant or non-hematopoietic malignant cells. The LAPTM5 level in HL-60 cells increased more significantly during TPA-induced monocyte/macrophage differentiation than during DMSO-induced granulocyte differentiation. Ectopic expression of GFP-LAPTM5 or LAPTM5 in HeLa cells exhibited the localization of LAPTM5 to the lysosome. In HeLa cells overexpressing LAPTM5, the Mcl-1 and Bid levels declined markedly and apoptosis was induced via Bak activation, Δψm loss, activation of caspase-9, -8 and -3, and PARP degradation without accompanying necrosis. However, these LAPTM5-induced apoptotic events except for the decline of Bid level were completely abrogated by concomitant overexpression of Mcl-1. The pan-caspase inhibitor (z-VAD-fmk) could suppress the LAPTM5-induced apoptotic sub-G1 peak by ~40% but failed to block the induced Δψm loss, whereas the broad-range inhibitor of cathepsins (Cathepsin Inhibitor I) could suppress the LAPTM5-induced apoptotic sub-G1 peak and Δψm loss, by ~22% and ~23%, respectively, suggesting that the LAPTM5-mediated Δψm loss was exerted at least in part in a cathepsin-dependent manner. Together, these results demonstrate that ectopic overexpression of LAPTM5 in HeLa cells induced apoptosis via cleavage of Mcl-1 and Bid by a LAPTM5-associated lysosomal pathway, and subsequent activation of the mitochondria-dependent caspase cascade
Torsional Vibration Transduction in a Solid Shaft by MPTs
In this study, we aim to investigate the feasibility to use MPTs (Magnetostrictive Patch Transducers) for torsional vibration measurement in solid ferromagnetic cylinders. MPTs consisting of thin magnetostrictive patches, permanent magnets and a solenoid coil have been widely used for elastic wave transduction in the ultrasound frequency range [1] but they have been seldom used for sonic-frequency range vibration measurement, in spite of their unique wireless transduction characteristics. While a MPT was used in Ref. [2] to perform torsional modal testing in a hollow cylinder or a pipe having relatively small torsional rigidity, no investigation has been reported yet on the use of MPTs in “solid” “ferromagnetic” shafts, common torsional power carrying elements in machines.While we will be mainly focused here on the torsional wave measurement in stationary shafts, the MPT-based torsional measurement can be also applied to rotating shafts. Because the torsional rigidities of solid shafts are much larger than those of hollow cylinders of the same radii, it is important to find optimal MPT configurations, such as the optimal number of rectangular patches to be installed around the surface of a solid shaft. Thereby, we performed numerical investigations and accordingly designed a series of experiments for torsional vibration testing in steel shafts. The actual modal testing experiments with the designed MPTs were found to predict the torsional Eigen-frequencies and Eigen-modes that agree well with the theoretical predictions. Also the relation between the measured vibration signals from MPTs and those from strain gages was checked experimentally and in fact, the experimental result favorably agreed with the theoretical prediction. Potential applications of the MPT-based torsional vibration measurement technique in rotating solid shafts for structural health monitoring are also briefly discussed
Diffusion on a heptagonal lattice
We study the diffusion phenomena on the negatively curved surface made up of
congruent heptagons. Unlike the usual two-dimensional plane, this structure
makes the boundary increase exponentially with the distance from the center,
and hence the displacement of a classical random walker increases linearly in
time. The diffusion of a quantum particle put on the heptagonal lattice is also
studied in the framework of the tight-binding model Hamiltonian, and we again
find the linear diffusion like the classical random walk. A comparison with
diffusion on complex networks is also made.Comment: 5 pages, 6 figure
Diffuse Alveolar Hemorrhage in a 39-year-old Woman: Unusual Initial Presentation of Microscopic Polyangiitis
Microscopic polyangiitis (MPA) is a necrotizing vasculitis involving the small vessels without granulomatous inflammation. Most MPA initially presents with renal involvement without pulmonary involvement. Isolated and initially presenting alveolar hemorrhage is very rare. The patient was a 39-year-old female with a progressive cough, dyspnea, and blood-tinged sputum for the previous 5 days. We determined that her condition was MPA though VATS lung biopsy and renal biopsy. After 2 months of steroid therapy, the chest lesions had improved. We report here a rare case of MPA with isolated and initial involvement of the lung with a review of the literature
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