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    Additional file 1 of Inhibition of Dickkopf-1 enhances the anti-tumor efficacy of sorafenib via inhibition of the PI3K/Akt and Wnt/β-catenin pathways in hepatocellular carcinoma

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    Additional file 1: Supplementary Figure 1. The effects of LEN, WAY or their combination treatment on cell viability or colony formation in HCC cells. Supplementary Figure 2. Combination effects of SOR + WAY treatment on tumor progression in xenograft mouse model. Supplementary Figure 3. SOR + WAY treatment regulates PI3K/Akt and Wnt/β-catenin pathways in HCC. Supplementary Figure 4. The combination effects of SOR + WAY treatment under condition of PI3K activation. Supplementary Figure 5. Correlation between DKK1 expression and immune cell infiltration. Supplementary Table 1. Primary and secondary anti-bodies used in this study. Supplementary Table 2. Primer sequences used in the qRT-PCR
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