HIV, HBS and HCV in Dump Site Workers of Erbil Governorate

This research targeted eighty-nine males working in Kany Qrzhala, dumpsite. Age and gender comparable apparently healthy subjects were selected as healthy controls, and both of the groups were obliged to fill the study's questionnaire. Further, venous blood samples were collected from each individual for serum collection. The accumulated sera reserved for the sero-prevalence for antibodies tests of Human Immunodeficiency Virus, Hepatitis B Surface Antigen and Hepatitis C Virus, (HIV), (HBS), (HCV) respectively. The automated immunoassay analyzer Cobas E411 facilitated the conducting of the mentioned tests. The serum concentration of HIV and HBS antibodies of dumpsite workers revealed a significant increase when compared to the healthy group, while the HCV antibody serum concentration presented no significant alteration when comparing dumpsite workers to the healthy controls. The antibodies presence in the sera that belonged to workers is an indicator of exposure to the viruses due to unsanitary health conditions. This may pose a public health risk to the workers themselves, in addition to the people they are in contact with, including their families

Anti-Toxoplasma, Anti-rubella, and Anti-cytomegalovirus Antibodies in Dumpsite Workers of Erbil Governorate

The present study aimed to detect the presence of anti-Toxoplasma, anti-rubella, and anti-cytomegalovirus (CMV) antibodies in the sera of dumpsite workers of Erbil Governorate. Eighty nine male dumpsite (Kany Qrzhala, Erbil Governorate) workers were included in this study. Serum was obtained for the detection of anti-Toxoplasma, anti-rubella, and anti-CMV antibodies using an automated cobas e411 immunoassay analyzer. No anti-Toxoplasma IgM antibodies were detected in any of the workers’ sera, while (25.84%) showed a positive result for anti-Toxoplasma IgG antibodies. All workers’ sera had no anti-rubella IgM and IgG2 antibodies, while (62.92%) of them revealed the presence of IgG1 in their sera. Anti-CMV IgM was found in (2.25%) of the sera, while (13.50%) of the sera revealed the presence of anti-CMV IgG antibodies

Some Immunological and Hematological Parameters among Refugees in Kawergosk Camp – Erbil Governorate

The study included 258 Syrian refugees of different ages and sex and another 60 volunteers as control group (C.G). These refugees were in Kawergosk camp in Erbil Governorate. Blood was collected from each individual for the estimation of white blood cell (WBC), eosinophil, iron, hemoglobin (Hb), and immunoglobulin E (IgE) levels. Mean serum levels of IgE among male and female refugees showed highly significant increasing when compared to C.G. Most of the refugees had normal iron levels, where iron concentrations were more than 65 mg/dl among 67 males and more than 50 mg/dl among 104 females and 48 children, while some had iron deficiency in which the majority were female (9 males, 24 females, and 6 children had iron deficiency). In addition, Hb concentrations were normal among 65 males (more than 13.0 g/dl), 89 females (more than 11.0 g/dl), and 48 children (more than 12.0 g/dl). However, anemia was found among 8 men, 42 women, and 6 children. It was revealed that there was a highly significant rising in eosinophils in male and female refugees in comparison to C.G. WBC count is non-significantly slightly increased in both male’s and female’s refugees when compared to C.G

Age of women as a parameter Affecting CA-125, TSH and CBC

One of the Cancer’s antigens is the CA125, which is a protein antigen, found at excessively high levels in females characterized with ovarian cancer. It is suggested for ovarian cancer screening of women that are at higher risk to get the disease, despite its limited sensitivity and specificity. This study is conducted to identify possible correlations between CA125 and TSH levels with parameters of hematological origin among women of different ages. This study included 44 healthy looking females. Most but not all patients were from Erbil. The study revealed that, CA125 and TSH levels were not associated. Also, the elevation of the CA125 levels in the females could be related to other non-cancerous factors such as menstrual cycle, or postmenopausal. Also WBC parameters and Hb levels were not affected by CA125. The only parameter that was affected by CA125 elevation was RBCs. The research recorded a significant difference of RBC between patient group and control group. Also recorded, no difference to be considered as an indication related to the difference in women age

Occupational Exposures and Associated Health Effects among Dumpsite Workers

Eighty-nine male workers from the landfill site in (Kany Qrzhala), Erbil, Iraq, aged from 12-65 years were investigated in this study. Each one had filled out a questionnaire sheet. Plus, a 7 ml of venous blood samples were collected from them. Total IgE and Syphilis antibodies were detected. Thus, CBC was conducted on each sample. The results recorded 92.13% of the workers lived in rural areas, while 7.87% lived in urban areas. Further, there were 58.43% smokers and 41.57% non-smokers. Furthermore, the research sample contained 38.20% single, and 61.80% married people. As education illustrated, 37.08% had no schooling, primary school education 40.45%, less than 20% had secondary school education, 2.25% acquired a diploma, and a B.Sc. degree. The serum concentration of total IgE of dumpsite workers revealed a significant increase when compared to the healthy group. None of the workers' sera revealed Syphilis antibodies except one case which was positive; however, it shows non-significant difference between both groups. WBC count was soared significantly in dumpsite workers when compared to the healthy individuals, yet, lymphocyte and granulocyte numbers showed non-significant increment, while monocyte number showed an insignificant rise in workers as compared to healthy group. The number of RBC's and Hb level of the Landfill workers exhibited a substantial increase. Even though, both groups' platelets did not show significant variance. The rise in WBC counts and IgE levels may be due to the exposure of these workers to allergens at the dumpsites as for allergies are the common consequence when exposed to waste and garbage

A Microbiological Survey of Ear Infections in Inhabitants of Erbil City

this study was carried out to indicate the number of infected individuals with ear infection from different genders and ages determine the antibiotic sociability for the ear swab bacterial isolates. A total of 82 ear swabs were obtained in Erbil City from various hospitals and labs. Males made up 48 (59%) of the 81 samples, while females made up 33 (41%). 0-10 years had the most bacteria isolated from ear swabs, followed by 11-20 years and then 21-40 years. Pseudomonas spp. were the most prevalent bacteria found in all of the swabs (43 percent). Pathogenic bacteria were found in 70% of the samples, while no growth was seen in 30% of the swabs. Many bacterial isolates were found to be sensitive to the antibiotic Amikacin, which was determined to have the best effect on 35 of them. Clotrimazole was shown to be the least effective antibiotic on numerous bacterial strains, with 19 being resistant

Hepatoprotective Effect of Alpinetin on Thioacetamide-Induced Liver Fibrosis in Sprague Dawley Rat

Alpinetin is an original medicinal plant flavonoid derived from Alpinia katsumadai and has several biological activities. The current research aimed to evaluate the hepatoprotective effects of Alpinetin against thioacetamide (TAA)-induced liver cirrhosis in rats. Five groups of rats were utilized in this study. Hepatic injury was measured macroscopically and microscopically for entire groups. The rats’ body weight was significantly lower in the TAA control group, likened to rats fed with Silymarin or Alpinetin groups, while liver weight was significantly greater in the TAA control group when equated to rats nourished with Alpinetin groups. A histopathological investigation of hepatic tissues displayed that TAA remarkably induced hepatocyte necrosis and gristly connective tissue propagation in the TAA control group. Alpinetin implicitly decreased the influence of TAA toxicity and diminished fibrosis of liver tissues. The TAA control group presented an increase in liver enzymes (ALP, ALT, and AST) and a decrease in total protein and albumin. Rats who were fed Alpinetin had significantly lower hepatic enzyme activity as well as augmented total protein and albumin, yet they were close to the normal range. Superoxide dismutase (SOD) and Catalase (CAT) enzymes in hepatic homogenate were significantly reduced, and malondialdehyde (MDA) was meaningfully elevated in the TAA control group, while rats fed with Alpinetin had significantly increased SOD and CAT achievement and depressed MDA level. Alpinetin-gavaged groups had reduced levels of Tumor necrosis factor-alpha (TNF-α) and Interleukin-6 (IL-6), significantly down-regulated Proliferating cell nuclear antigen (PCNA), Alpha-smooth muscle (α-SMA), and reduced hepatic stellate cell activity. However, the TAA control group significantly up-regulated PCNA and α-SMA and increased the activity of hepatic stellate cells. Alpinetin was nontoxic and could improve defensive mechanisms against hepatic tissue injury. Acute toxicity tests discovered no evidence of any toxic signs or dead rats, which highlights the safety of Alpinetin. Consequently, the investigation´s outcomes revealed that the hepatoprotective effects of Alpinetin in TAA-induced hepatic impairment might be due to reduced TAA toxicity, increased protein and albumin, increased SOD and CAT levels, reduced MDA levels, and modulation of inflammatory cytokines and their anti-oxidant activities, and suppressed PCNA and α-SMA

Hepatoprotective Effects of Biochanin A on Thioacetamide-Induced Liver Cirrhosis in Experimental Rats

The protective effect of biochanin A (BCA) on the histopathology, immunohistochemistry, and biochemistry of thioacetamide (TAA)-induced liver cirrhosis in vivo was investigated. There was a significant reduction in liver weight and hepatocyte propagation, with much lower cell injury in rat groups treated with BCA (25 mg/kg and 50 mg/kg) following a TAA induction. These groups had significantly lower levels of proliferating cell nuclear antigen (PCNA) and α-smooth muscle actin (α-SMA). The liver homogenates showed increased antioxidant enzyme activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx), as well as decreased malondialdehyde (MDA) levels. The serum biomarkers associated with liver function, namely alkaline phosphatase (ALP), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and gamma glutamyl transaminase (GGT), returned to normal levels, comparable to those observed in both the normal control group and the reference control group. Taken together, the normal microanatomy of hepatocytes, the inhibition of PCNA and α-SMA, improved antioxidant enzymes (SOD, CAT, and GPx), and condensed MDA with repairs of liver biomarkers validated BCA’s hepatoprotective effect