Expression of miRNA precursor and its major mature form in 15 mouse tissues.

<p>A heat map was constructed using GenePattern software based on the normalized miRNA reads. Heat maps showed precursors and major forms to have similar patterns of expression.</p

Expression of miR-194-5p, miR-192-5p, and miR-215-5p in human colon cell lines.

<p>The level of expression is given in sequence counts per million.</p

Expression of mature miRNAs in 16 mouse tissues.

<p>Expression analysis was performed using real-time RT-PCR. The expression levels were normalized to U6 snRNA. (a) miR-194-5p expression, (b) miR-192-5p expression, (c) miR-215-5p expression. * Preferential expressed tissues identified by ANOVA (<i>P</i><0.05) and Turkey's HSD test</p

Reads per million of miR-194-5p, miR-192-5p, and miR-215-5p in human colon cell lines.

<p>Reads per million of miR-194-5p, miR-192-5p, and miR-215-5p in human colon cell lines.</p

Expression of the miRNA precursor and its major and minor mature forms in 15 mouse tissues.

<p>Heat maps were constructed using GenePattern software based on the normalized miRNA reads. This heat map shows precursors and minor forms to have different patterns of expression in many paralogous families.</p

Tissue coexpression scores of major/minor pairs.

<p>Selection was based on the score ranked top 10% and Fisher exact test between minor forms with <i>P</i> values below 0.05 in particular tissues. If the minor form did not have any reads, then the coexpression score of its major/minor pair was considered to be zero.</p><p>BM: bone marrow, Thy: thymus, Spl: Spleen, Lym: lymph, Bra: brain, Lung: lung, Liv: Liver, Kid: kidneys, Pan: pancreas, Ski: skin, Sal: salivary glands, Tes: testes, Ova: ovary.</p

Tissue coexpression score of miR-194-5p/miR-215-5p and miR-194-5p/miR-192-5p.

<p>The coexpression score was zero for all miRNA with no reads.</p

Potential HNF1 and HNF4 binding site in the promoters of pri-miR-194-1/miR-215 and miR-194-2/miR-192 genes in different species.

<p>Transcription binding sites were predicted using Motif-based sequence analysis tools.</p

Locations and expressions of the host genes and minor forms of mouse miR-128-1, 2 in 16 mouse tissues.

<p>(a) Structure of R3hdm1 as miR-128-1 host gene. (b) Structure of Arpp21 as miR-128-2 host gene. (c) qRT-PCR analysis of R3hdm1 expression, the levels of expression were normalized to 18S rRNA. (d) qRT-PCR analysis of Arpp21 expression, the levels of expression were normalized to 18S rRNA. (e) qRT-PCR analysis of the expression of miR-128-1-5p and miR-128-2-5p, the levels of expression were normalized to U6 snRNA. * Preferential expressed tissues identified by ANOVA (<i>P</i><0.05) and Turkey's HSD test.</p

Forest plot on the association between <i>SULT1A1</i> Arg213His polymorphism and UADT cancer risk in dominant model.

<p>Forest plot on the association between <i>SULT1A1</i> Arg213His polymorphism and UADT cancer risk in dominant model.</p