235 research outputs found

    A Study On The Relationship Between Exhibition Experience And Behavioral Intention, And The Mediating Effect Of Satisfaction And Brand Assets In Corporate Promotion Exhibition Halls

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    Currently, Korean companies operate corporate promotion halls, memorial halls and museums, centering on large corporations, making them a place for long-term communication beyond the short-term contact with consumers. In addition, companies have provided recently virtual exhibition experiences through the homepage or apps to the corporate publicity exhibition halls, which are operated by the company, and are being developed in parallel with the existing exhibition experiences. Therefore, this study conducted an empirical analysis to find out the effect of the exhibit experience of the corporate publicity exhibition hall on the consumer behavioral intention with the subject of the visitors who have experienced the exhibition experience of the domestic corporate publicity exhibition hall. Followings are the implications for the results. First, the corporate publicity exhibition hall did not have a specific effect on the behavioral intention of customers simply by exhibiting and viewing. This indicates that companies that operate or prepare to open the corporate publicity exhibition hall should avoid such simple experiences or simple viewing facilities. Second, the corporate publicity exhibition hall cannot induce customers' behavior simply by exhibiting experiences. The results will be more efficient when the corporate publicity exhibition hall is operated in combination with the brand assets of the company presented in this study or tangible and intangible assets of other companies. Third, as derived from the results of the study, corporate product brands are boldly exposed to consumers and very sensitive to consumers, affecting their behavioral intentions. The positive image of a product brand will lead to satisfaction and behavioral intentions, which in turn will affect the company's sales growth. Therefore companies should be very careful in managing their product brand. The academic significance of this study is in that it investigated the relationship between satisfaction, brand assets, and behavioral intention through the exhibition experience in the corporate publicity exhibition hall by conducting empirical analysis of the relationship systematically. In addition, it is expected to be used as a practical basic material that can be more practical in producing exhibition experiences when newly opening a corporate publicity exhibition hall or remodeling an existing corporate publicity exhibition hall. In the follow-up study, in order to provide the best exhibition experience to visitors to a company publicity exhibition hall, various variables such as human and material elements of the company publicity exhibition hall, such as how to guide at an information desk, the contact point with customers as well as four elements of experience. In addition, it will have its own meaning if research is conducted on local small and medium-sized businesses in addition to the corporate publicity exhibition hall centered on large companies

    A Study on the Relationship between Physical Education Environment and Recommendation Intention and the Moderating Effect of University Image

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    Universities providing educational services are constantly improving their educational environment by recognizing the importance of physical educational environment. However, most of the existing studies related to education services of universities have been limited to satisfaction with education services and academic achievement. It is time to increase the competitiveness of universities through the behavior intention of positive recommendations by encourage students as beneficiaries of educational services to take positive actions and psychology and promoting their image of universities. In this study, in order to understand the influence of the educational environment that affect the positive recommendation intention of the students, the relationship between the university image and the recommendation intention is examined in terms of the facility-centered educational environment factors from the perspective of the student who is the beneficiary of the educational service. To achieve the purpose of this study, a survey was conducted on university students studying in Busan, South Korea. The sample obtained through the questionnaire was refined and then analyses were conducted on demographic analysis, validity analysis, reliability analysis, correlation analysis, multiple regression analysis, and moderating regression analysis by using SPSS Version 21. The results and implications of this study are as follows. First, the physical educational environment factors of universities including indoor environment, external environment, operation management and convenience were found to have relevant effect on the recommendation intention. Therefore, hypothesis 1-1, hypothesis 1-2, hypothesis 1-3, and hypothesis 1-4 were all supported; therefore, hypothesis 1 was adopted. These results prove that the positive effect on the students from the physical environment of the university is not limited to specific factors. Therefore, universities need to manage all the factors of physical education environment to encourage students' positive recommendation intention. Furthermore, it is necessary to have continuous interest and improvement in physical education environment. Second, this study examined the moderating effect of university image verified in the relationship between physical education environment and recommendation intention. The university image had a significant moderating effect on the relationship between indoor environment, external environment, convenience and recommendation intention which are sub-variables of physical environment of education. So, hypothesis 2-1, hypothesis 2-2, and hypothesis 2-4 were supported. However, since the operation management did not show significant influence, hypothesis 2-3 was rejected. So, hypothesis 2 was partially supported. Therefore, universities should pay constant attention to and strive for not only physical environment of education but also improved university image. Despite the results of this study, I would like to suggest future research directions based on the limitations of this study. In the follow-up study, if the study is conducted through samples from more various regions, the results of the study can be generalized. In addition, if the detailed items are studied on regional study and the classification of the education system such as the national universities, the private universities, the two-year colleges, and other forms of four-year universities, the study would be more effective

    Histidine 454 plays an important role in polymerization of human glutamate dehydrogenase

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    AbstractAlthough previous chemical modification studies have suggested several residues to be involved in the maintenance of the quaternary structure of glutamate dehydrogenase (GDH), there are conflicting views for the polymerization process and no clear evidence has been reported yet. In the present study, cassette mutagenesis at seven putative positions (Lys333, Lys337, Lys344, Lys346, Ser445, Gly446, and His454) was performed using a synthetic human GDH gene to examine the polymerization process. Of the mutations at the seven different sites, only the mutagenesis at His454 results in depolymerization of the hexameric GDH into active trimers as determined by HPLC gel filtration analysis and native gradient polyacrylamide gel electrophoresis. The mutagenesis at His454 has no effects on expression or stability of the protein. The KM values for NADH and 2-oxoglutarate were 1.5-fold and 2.5-fold greater, respectively, for the mutant GDH than for wild-type GDH, indicating that substitution at position 454 had appreciable effects on the affinity of the enzyme for both NADH and 2-oxoglutarate. The Vmax values were similar for wild-type and mutant GDH. The kcat/KM value of the mutant GDH was reduced up to 2.8-fold. The decreased efficiency of the mutant, therefore, results from the increase in KM values for NADH and 2-oxoglutarate. The results with cassette mutagenesis and HPLC gel filtration analysis suggest that His454 is involved in the polymerization process of human GDH

    Effects of biofeedback-based sleep improvement program on urinary symptoms and sleep patterns of elderly Korean women with overactive bladder syndrome

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    Background The prevalence of overactive bladder syndrome (OAB) increases with age. Sleep disturbances in elderly individuals with OAB is a common problem. The purpose of this study was to examine the effects of a biofeedback-based sleep improvement (BBSI) program on urinary symptoms and sleep patterns in elderly Korean women with OAB. Methods A non-equivalent control group pre−/post-test design was used. Elderly women with OAB were assigned to an intervention group (n = 20) or a control group (n = 18). The BBSI program was implemented in the intervention group for 12 weeks, while two educational sessions of general sleep hygiene and lifestyle modification were provided to the control group. Using SPSS 23.0, the data were analyzed by descriptive analysis using the chi-square test, Fishers exact test, Mann-Whitney test, and Wilcoxon test. Results After the 12-week BBSI program, significant improvements were found in the intervention groups the square root of the mean squared differences of successive R-R intervals (p = 0.025), low frequency/high frequency ratio (p = 0.006), and epinephrine (p = 0.039). We also observed a significant difference in urinary symptoms, sleep efficiency, wake after sleep onset, number of awakenings, and number of awakenings within 3 h after sleep onset (p < 0.001, p = 0.004, p = 0.001, p = 0.001, and p = 0.048, respectively). However, no significant changes were found in these variables in the control group. Conclusions The BBSI program effectively improved urinary symptoms and sleep patterns of elderly Korean women with OAB. Further longitudinal research is required to investigate the sustainability and effects of the BBSI program. Trial registration KCT0003882. Date of registration: 02/05/2019. Retrospectively registered.This research was supported by the Bisa Research Grant of Keimyung University in 2017. This funder had no role in the study design; data collection, analysis, or interpretation; writing the manuscript; or the decision to submit the paper for publication

    A case of emphysematous hepatitis with spontaneous pneumoperitoneum in a patient with hilar cholangiocarcinoma

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    An 80-year-old woman with hilar cholangiocarcinoma was hospitalized due to sudden-onset abdominal pain. Computed tomography revealed hepatic necrosis accompanied with emphysematous change in the superior segment of the right liver (S7/S8), implying spontaneous rupture, based on the presence of perihepatic free air. Although urgent percutaneous drainage was performed, neither pus nor fluids were drained. These findings suggest emphysematous hepatitis with a hepatic mass. Despite the application of intensive care, the patient's condition deteriorated rapidly, and she died 3 days after admission to hospital. Liver gas has been reported in some clinical diseases (e.g., liver abscess) to be caused by gas-forming organisms; however, emphysematous hepatitis simulating emphysematous pyelonephritis is very rare. The case reported here was of fatal emphysematous hepatitis in a patient with hilar cholangiocarcinoma

    Congenital Epidermoid Cyst of the Oral Cavity: Prenatal Diagnosis by Sonography

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    Epidermoid cysts are benign developmental anomalies that are rarely observed in the oral cavity of neonate. If large in size, especially in the developing fetus or newborn infant, they can cause swallowing difficulty and occasionally respiratory difficulty. We report a case of epidermoid cyst in the oral cavity detected prenatal sonography. The sonographic finding was large cystic mass, measuring 30×25 mm. In this case, supplies and equipment for an emergency tracheostomy were made available prior to the delivery. However, the infant did not require intervention to secure the airway. The lesion was surgically excised, and histologic diagnosis was epidermoid cyst. After 6 months of follow up, the cyst had not recurred. This case illustrates the value of accurate prenatal diagnosis and planned perinatal management using a team approach

    The corrected QT (QTc) prolongation in hyperthyroidism and the association of thyroid hormone with the QTc interval

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    PurposeVentricular repolarization is assessed using the QT interval corrected by the heart rate (QTc) via an electrocardiogram (ECG). Prolonged QTc is associated with an increased risk of arrhythmias and cardiac mortality. As there have been few reports regarding the effects of hyperthyroidism on ventricular repolarization, we studied the association between serum free thyroxine (free T4 [fT4]) and thyroid stimulating hormone (TSH) levels and the QTc interval.MethodsThirty-eight patients with hyperthyroidism (<30 years old) were included, and we used their clinical records and available ECGs (between August 2003 and August 2011) to evaluate the association between their fT4 and TSH levels and their QTc interval. In addition, we studied the ECGs of 72 age-matched patients with no hyperthyroidism (control group) and compared their data with that from the patients group.ResultsThe QTc duration in patients with hyperthyroidism was significantly prolonged compared to that in the control subjects (P<0.001). In addition, the number of hyperthyroid patients with abnormal prolonged QTc was significantly higher than that in the control group (P<0.001). Among the patients with hyperthyroidism, patients with prolonged QTc and borderline QTc had higher fT4 levels and there was positive correlation between their fT4 levels and their QTc interval (P<0.05). However, no correlation was observed between their TSH levels and their QTc interval.ConclusionWe report that hyperthyroidism is associated with QTc prolongation. The correlation between the fT4 levels and the QTc interval suggests that thyroid status is associated with QTc values and the risk of cardiac mortality

    Development of the Korea-Polyenvironmental Risk Score for Psychosis

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    Objective: Comprehensive understanding of polyenvironmental risk factors for the development of psychosis is important. Based on a review of related evidence, we developed the Korea Polyenvironmental Risk Score (K-PERS) for psychosis. We investigated whether the K-PERS can differentiate patients with schizophrenia spectrum disorders (SSDs) from healthy controls (HCs). Methods: We reviewed existing tools for measuring polyenvironmental risk factors for psychosis, including the Maudsley Environmental Risk Score (ERS), polyenviromic risk score (PERS), and Psychosis Polyrisk Score (PPS). Using odds ratios and relative risks for Western studies and the "population proportion" (PP) of risk factors for Korean data, we developed the K-PERS, and compared the scores thereon between patients with SSDs and HCs. In addition, correlation was performed between the K-PERS and Positive and Negative Syndrome Scale (PANSS). Results: We first constructed the "K-PERS-I," comprising five factors based on the PPS, and then the "K-PERS-II" comprising six factors based on the ERS. The instruments accurately predicted participants' status (case vs. control). In addition, the K-PERS-I and -II scores exhibited significant negative correlations with the negative symptom factor score of the PANSS. Conclusion: The K-PERS is the first comprehensive tool developed based on PP data obtained from Korean studies that measures polyenvironmental risk factors for psychosis. Using pilot data, the K-PERS predicted patient status (SSD vs. HC). Further research is warranted to examine the relationship of K-PERS scores with clinical outcomes of psychosis and schizophrenia
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