Concurrent investigation of global motion and form processing in amblyopia: an equivalent noise approach

PURPOSE: Directly comparing the motion and form processing in neurologic disorders has remained difficult due to the limitations in the experimental stimulus. In the current study, motion and form processing in amblyopia was characterized using random dot stimuli in different noise levels to parse out the effect of local and global processing on motion and form perception. METHODS: A total of 17 amblyopes (8 anisometropic and 9 strabismic), and 12 visually normal subjects monocularly estimated the global direction of motion and global orientation in random dot kinematograms (RDK) and Glass patterns (Glass), whose directions/orientations were drawn from normal distributions with a range of means and variances that served as external noise. Direction/orientation discrimination thresholds were measured without noise first then variance threshold was measured at the multiples of the direction/orientation threshold. The direction/orientation and variance thresholds were modelled to estimate internal noise and sampling efficiency parameters. RESULTS: Overall, the thresholds for Glass were higher than RDK for all subjects. The thresholds for both Glass and RDK were higher in the strabismic eyes compared with the fellow and normal eyes. On the other hand, the thresholds for anisometropic amblyopic eyes were similar to the normal eyes. The worse performance of strabismic amblyopes was best explained by relatively low sampling efficiency compared with other groups (P < 0.05). CONCLUSIONS: A deficit in global motion and form perception was only evident in strabismic amblyopia. Contrary to the dorsal stream deficiency hypothesis assumed in other developmental disorders, deficits were present in both motion (dorsal) and form (ventral) processing

Sub-Nanosecond Time of Flight on Commercial Wi-Fi Cards

Time-of-flight, i.e., the time incurred by a signal to travel from transmitter to receiver, is perhaps the most intuitive way to measure distances using wireless signals. It is used in major positioning systems such as GPS, RADAR, and SONAR. However, attempts at using time-of-flight for indoor localization have failed to deliver acceptable accuracy due to fundamental limitations in measuring time on Wi-Fi and other RF consumer technologies. While the research community has developed alternatives for RF-based indoor localization that do not require time-of-flight, those approaches have their own limitations that hamper their use in practice. In particular, many existing approaches need receivers with large antenna arrays while commercial Wi-Fi nodes have two or three antennas. Other systems require fingerprinting the environment to create signal maps. More fundamentally, none of these methods support indoor positioning between a pair of Wi-Fi devices without~third~party~support. In this paper, we present a set of algorithms that measure the time-of-flight to sub-nanosecond accuracy on commercial Wi-Fi cards. We implement these algorithms and demonstrate a system that achieves accurate device-to-device localization, i.e. enables a pair of Wi-Fi devices to locate each other without any support from the infrastructure, not even the location of the access points.Comment: 14 page

Gravitational collapse of an isentropic perfect fluid with a linear equation of state

We investigate here the gravitational collapse end states for a spherically symmetric perfect fluid with an equation of state $p=k\rho$. It is shown that given a regular initial data in terms of the density and pressure profiles at the initial epoch from which the collapse develops, the black hole or naked singularity outcomes depend on the choice of rest of the free functions available, such as the velocities of the collapsing shells, and the dynamical evolutions as allowed by Einstein equations. This clarifies the role that equation of state and initial data play towards determining the final fate of gravitational collapse.Comment: 7 Pages, Revtex4, To appear in Classical and Quantum Gravit

On the genericity of spacetime singularities

We consider here the genericity aspects of spacetime singularities that occur in cosmology and in gravitational collapse. The singularity theorems (that predict the occurrence of singularities in general relativity) allow the singularities of gravitational collapse to be either visible to external observers or covered by an event horizon of gravity. It is shown that the visible singularities that develop as final states of spherical collapse are generic. Some consequences of this fact are discussed.Comment: 19 pages, To be published in the Raychaudhuri Volume, eds. Naresh Dadhich, Pankaj Joshi and Probir Ro

On-lattice agent-based simulation of populations of cells within the open-source chaste framework

Over the years, agent-based models have been developed that combine cell division and reinforced random walks of cells on a regular lattice, reaction-diffusion equations for nutrients and growth factors and ordinary differential equations (ODEs) for the subcellular networks regulating the cell cycle. When linked to a vascular layer, this multiple scale model framework has been applied to tumour growth and therapy. Here we report on the creation of an agent-based multiscale environment amalgamating the characteristics of these models within a Virtual Pysiological Human (VPH) Exemplar Project. This project enables re-use, integration, expansion and sharing of the model and relevant data. The agent-based and reactiondiffusion parts of the multiscale model have been implemented and are available for download as part of the latest public release of Chaste (“Cancer, Heart and Soft Tissue Environment”), (http://www.cs.ox.ac.uk/chaste/) version 3.1, part of the VPH Toolkit (http://toolkit.vph-noe.eu/). The environment functionalities are verified against the original models, in addition to extra validation of all aspects of the code. In this work, we present the details of the implementation of the agent-based environment, including the system description, the conceptual model, the development of the simulation model and the processes of verification and validation of the simulation results. We explore the potential use of the environment by presenting exemplar applications of the “what if” scenarios that can easily be studied in the environment. These examples relate to tumour growth, cellular competition for resources and tumour responses to hypoxia. We conclude our work by summarising the future steps for the expansion of the current system

Analysis and simulation of a magnetic bearing suspension system for a laboratory model annular momentum control device

A linear analysis and the results of a nonlinear simulation of a magnetic bearing suspension system which uses permanent magnet flux biasing are presented. The magnetic bearing suspension is part of a 4068 N-m-s (3000 lb-ft-sec) laboratory model annular momentum control device (AMCD). The simulation includes rigid body rim dynamics, linear and nonlinear axial actuators, linear radial actuators, axial and radial rim warp, and power supply and power driver current limits

The importance of planetary rotation period for ocean heat transport

The climate, and hence potential habitability, of a planet crucially depends on how its atmospheric and oceanic circulation transports heat from warmer to cooler regions. However, previous studies of planetary climate have concentrated on modelling the dynamics of their atmospheres whilst dramatically simplifying the treatment of the oceans, which neglects or misrepresents the effect of the ocean in the total heat transport. Even the majority of studies with a dynamic ocean have used a simple so-called aquaplanet having no continental barriers, which is a configuration which dramatically changes the oceanic dynamics. Here the significance of the response of poleward ocean heat transport to planetary rotation period is shown with a simple meridional barrier – the simplest representation of any continental configuration. The poleward ocean heat transport increases significantly as the planetary rotation period is increased. The peak heat transport more than doubles when the rotation period is increased by a factor of ten. There are also significant changes to ocean temperature at depth, with implications for the carbon cycle. There is strong agreement between the model results and a scale analysis of the governing equations. This result highlights the importance of both planetary rotation period and the ocean circulation when considering planetary habitability

North-South Distribution of Solar Flares during Cycle 23

In this paper, we investigate the spatial distribution of solar flares in the northern and southern hemisphere of the Sun that occurred during the period 1996 to 2003. This period of investigation includes the ascending phase, the maximum and part of descending phase of solar cycle 23. It is revealed that the flare activity during this cycle is low compared to previous solar cycle, indicating the violation of Gnevyshev-Ohl rule. The distribution of flares with respect to heliographic latitudes shows a significant asymmetry between northern and southern hemisphere which is maximum during the minimum phase of the solar cycle. The present study indicates that the activity dominates the northern hemisphere in general during the rising phase of the cycle (1997-2000). The dominance of northern hemisphere is shifted towards the southern hemisphere after the solar maximum in 2000 and remained there in the successive years. Although the annual variations in the asymmetry time series during cycle 23 are quite different from cycle 22, they are comparable to cycle 21.Comment: 6 pages, 2 figures, 1 table; Accepted for the publication in the proceedings of international solar workshop held at ARIES, Nainital, India on "Transient Phenomena on the Sun and Interplanetary Medium" in a special issue of "Journal of Astrophysics and Astronomy (JAA)