Re-creating legal space for the first law of Aotearoa-New Zealand

Some of the historic and contemporary statutory and case law examples of a hybrid Maori-British common law legal system in Aotearoa-New Zealand are discussed. The importance and role performed by the First Law, the tikanga Maori customary law is highlighted

Frozen rights?: The right to develop Maori treaty and aboriginal rights

Bishop Manuhuia Bennett often asked the question: "What did Maori call New Zealand before the arrival of the Pakeha [Europeans]?" After a deliberate pause, he would then simply utter: "Ours"

Analysis of types of questions asked by sixth grade children concerning social studies content.

Thesis (M.A.)--Boston Universit

Care of the Dying: The Doctor and Euthanasia

The quality of the doctor patient relationship is central in this discussion of the euthanasia problem. Robert Rizzo, Ph.D., is Assistant Professor in the Department of Religious Studies at Canisius College, Buffalo, N.Y. Joseph Yonder teaches medical ethics at Trocaire College, Buffalo, N.Y. and is also an Inhalation Therapy Technician at Buffalo\u27s Columbus Hospital

The Earth's Worst Climate Disaster

Scientists, environmentalists, and the wiser members of the political class worry today about global climate change. Will rising tides plunge Tokyo, London, and New York beneath the ocean’s waves? Will meltwater pouring off of North America shift the circulation of the North Atlantic Ocean and plunge Europe into an Ice Age? Yet, as worrisome as these prospects are, the Earth has faced far greater climatic catastrophes in the past. The greatest among these was the Paleoproterozoic Snowball Earth event, which 2.3 billion years ago smothered the planet with a blanket of ice for tens of millions of years

The distributions of functions related to parametric integer optimization

We consider the asymptotic distribution of the IP sparsity function, which measures the minimal support of optimal IP solutions, and the IP to LP distance function, which measures the distance between optimal IP and LP solutions. We create a framework for studying the asymptotic distribution of general functions related to integer optimization. There has been a significant amount of research focused around the extreme values that these functions can attain, however less is known about their typical values. Each of these functions is defined for a fixed constraint matrix and objective vector while the right hand sides are treated as input. We show that the typical values of these functions are smaller than the known worst case bounds by providing a spectrum of probability-like results that govern their overall asymptotic distributions.Comment: Accepted for journal publicatio

Hypothalamic excitatory amino acid receptors mediate stress-induced tachycardia in rats

The role of hypothalamic excitatory amino acid (EAA) receptors in mediating the cardiovascular response to stress was examined using conscious chronically instrumented rats. Microinjection of the EAA agonists N-methyl-D-aspartic acid (NMDA; 1-10 pmol), alpha-amino-3-hydroxy-5-methyl-4-isooxazolepropionic acid (AMPA; 0.3-3.0 pmol), or kainic acid (0.1-1.0 pmol) into the dorsomedial hypothalamus (DMH) elicited dose-related increases in heart rate and modest elevations in arterial pressure. Local microinjection of the NMDA antagonist 2-amino-5-phosphonopentanoic acid (AP5; 100 pmol) selectively blocked NMDA-induced cardiovascular changes, whereas the non-NMDA EAA antagonist 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX; 50 pmol) selectively blocked the responses to AMPA and kainic acid. In the stress trials, microinjection of the nonselective EAA antagonist kynurenic acid (1-10 nmol) into the DMH blocked air stress-induced tachycardia in a dose-related manner. Similar injection of kynurenic acid at sites lateral or posterior to the DMH or injection of xanthurenic acid (a structural analogue of kynurenic acid with no antagonistic properties at EAA receptors) into the DMH failed to influence air stress-induced cardiovascular changes. Injection of either AP5 or CNQX into the DMH at doses shown to be selective for their respective EAA receptor subtypes also attenuated air stress-induced tachycardia. Thus activity at EAA receptors in the DMH appears to be necessary for the generation of stress-induced changes in heart rate

GABA\u3csub\u3eA\u3c/sub\u3e and excitatory amino acid receptors in dorsomedial hypothalamus and heart rate in rats

We have previously shown that microinjection of drugs that interfere with the function of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) into the hypothalamus produces cardiorespiratory and behavioral changes resembling those seen in emotional stress. The purpose of this study was to determine whether excitatory amino acids (EAAs) can produce a cardiovascular response similar to that caused by the GABAA receptor antagonist bicuculline methiodide (BMI) when microinjected at the same hypothalamic site in urethan-anesthetized rats and to clarify the precise locus of action of these agents. N-methyl-D-aspartic acid (NMDA, 0.68-6.8 pmol/50 nl) and kainic acid (KA, 0.47-4.7 pmol/50 nl) produced dose-related increases in heart rate and blood pressure when injected at sites in the dorsomedial hypothalamus reactive to BMI (20 pmol/50 nl). Higher doses of NMDA (68 pmol), however, failed to elicit consistent increases in heart rate and blood pressure when injected at these same sites. The effects of NMDA were selectively blocked by the NMDA receptor antagonist 2-amino-5-phosphonopentanoic acid, whereas the effects of KA were selectively blocked by the non-NMDA EAA receptor antagonist 6-cyano-7-nitroquinoxaline-2,3-dione. These results demonstrate that 1) blockade of inhibitory amino acid receptors or stimulation of EAA receptors in the dorsomedial nucleus of the hypothalamus produces tachycardic and pressor responses in urethan-anesthetized rats and 2) use of high doses of EAAs may be an unreliable method of evoking local neuronal excitation in certain regions of the central nervous system