Characteristics of the study population of 192,432 Swedish women and their newborns.

<p>Characteristics of the study population of 192,432 Swedish women and their newborns.</p

Maternal height in Swedish women and the prevalence of infants born preterm (<37 weeks of gestation), very preterm (<32 weeks of gestation), or extremely preterm (<28 weeks of gestation).

<p>Maternal height in Swedish women and the prevalence of infants born preterm (<37 weeks of gestation), very preterm (<32 weeks of gestation), or extremely preterm (<28 weeks of gestation).</p

Histogram showing the frequency distribution of children studied according to birth weight standard deviation scores (SDS).

<p>Histogram showing the frequency distribution of children studied according to birth weight standard deviation scores (SDS).</p

Characteristics of the 143 children studied according to their birth weight standard deviation scores (SDS).

<p>Age data are mean ± SD; other data are means and 95% confidence intervals adjusted for confounding factors in the multivariate models.</p><p>Characteristics of the 143 children studied according to their birth weight standard deviation scores (SDS).</p

Insulin sensitivity and other parameters of glucose homeostasis according to menarcheal age groups: Early (n = 13), Average (n = 28), and Late (n = 13).

<p>Data are adjusted means from multivariate models with respective 95% confidence intervals. *p<0.05 and **p<0.01 vs Early group; †††p<0.001 vs Late group.</p

Height and BMI SDS corrected for mean parental height and mid-parental BMI SDS, respectively, among the offspring of mothers of different ages at childbirth.

<p>Data are estimated marginal means and 95% confidence intervals, adjusted for other confounding factors in multivariate models (including paternal age). *p&lt;0.05 and **p&lt;0.01 vs children of mothers aged &lt;30 years at childbirth. Abdominal adiposity is represented by the android fat to gynoid fat ratio. The 95% confidence intervals for the differences between groups are provided in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0058869#pone.0058869.s001" target="_blank">Table S1</a>.</p

Incidence of new cases of type 1 diabetes mellitus per 100,000 age-matched inhabitants diagnosed in Auckland (New Zealand) during 1990–2009.

<p>A) For all children &lt;15 yr; B) for children 0–4 yr (solid gray line), 5–9 yr (dashed gray line), and 10–14 yr (solid black line).</p

Summary of the study's recruitment process.

<p>¹ OS_A children had been conceived via ovarian stimulation, and were examined in Savage <i>et al. </i><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0058869#pone.0058869-Savage1" target="_blank">[13]</a>. ² Controls were friends of OS_A children to ensure similar age group, ethnicity, and socio-economic status. ³ 22 children were born small-for-gestational age and/or premature; 5 were pubertal; 3 were born to a mother with gestational diabetes/glucose intolerance; and one child was on medication known to influence growth.</p

Lipid and IGF profiles in childhood according to maternal age at childbirth.

<p>Data are estimated marginal means and 95% confidence intervals adjusted for other confounding factors in the multivariate models (including paternal age). *p&lt;0.05 and **p&lt;0.01 vs children of mothers aged &lt;30 years at childbirth. The 95% confidence intervals for the differences between groups are provided in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0058869#pone.0058869.s001" target="_blank">Table S1</a>.</p

Parameters of glucose homeostasis among boys and girls according to maternal age at childbirth.

<p>Data are estimated marginal means and 95% confidence intervals adjusted for other confounding factors in the multivariate models (including paternal age). ^*p&lt;0.05 and ^**p&lt;0.01 for comparisons with &lt;30 group. The 95% confidence intervals for the ratios between estimated marginal means are provided in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0058869#pone.0058869.s002" target="_blank">Table S2</a>.</p