Radiofrequency ablation of malignant renal tumor: report of three cases

Three cases of radiofrequency ablation of small malignant renal tumor performed at Clinica Internacional, in Lima, Peru, were presented. Two female patients aged 69 and 37; and a male patient (with only one kidney) of 65 years old, are reported. They presented incidental diagnosis of small single kidney tumor (less than 3 cm) by imaging studies, showing radiological signs of malignancy in all three cases. The patients did not receive surgical treatment for different reasons. A renal biopsy was performed for anatomopathological confirmation (AP) and, immediately after, the radiofrequency thermal ablation (RF) of such renal tumors with excellent results after the procedure and in the subsequent follow-up.&nbsp

Ablación por radiofrecuencia de tumor renal maligno: reporte de tres casos

Se presentan tres casos de ablación por radiofrecuencia de tumor renal maligno pequeño realizados en la Clínica Internacional, en Lima, Perú. Se reportan dos pacientes mujeres de 69 y 37 años de edad, y un paciente varón monorreno (tiene solo riñón derecho) de 65 años de edad, quienes presentaron diagnóstico incidental de tumor renal único pequeño (menor de 3 cm) por estudios de imagen, el cual tuvo signos radiológicos de malignidad en los tres casos. Los pacientes no fueron tributarios de tratamiento quirúrgico por diferentes motivos. Se realizó una biopsia renal para confirmación anatomopatológica (AP) e inmediatamente después, ablación térmica por radiofrecuencia (RF) de dichos tumores renales con buenos resultados tras el procedimiento y en el seguimiento posterior

Control de campo de ayudas agrarias basado en telefonía móvil

Hoy día, la mayoría de los datos que se manejan llevan asociados una componente geográfica. Bajo este contexto asistimos a un acercamiento de tecnologías empleadas por usuarios expertos hacia usuarios genéricos. En este marco se plantea la integración de las nuevas tecnologías en el control de las ayudas agrarias. Actualmente, los procesos de control de ayudas agrarias se basan fundamentalmente en visitas de campo con objeto de certificar el uso del suelo. Esta metodología de control origina una movilización importante de personal y equipos, empleando simultáneamente dispositivos como cámara fotográfica, tablet-PC, GPS, etc. El objetivo de este proyecto ha sido el desarrollo de una aplicación para telefonía móvil aprovechando los distintos sensores que se encuentran integrados en él, utilizando terminales que añaden nuevas funcionalidades, asegurando la integridad de la información, mejorando su correcta interpretación así como estableciendo diferentes canales de difusión. El proyecto se ha desarrollado bajo Android, empleando librerías de código abierto y de ejecución independiente al fabricante del dispositivo telefónico. El resultado es un software que integra información de diferentes sensores, presentando el terminal móvil apto para los trabajos de control de campo, reduciendo el material a emplear y mejorando la integridad de la información.Today, most data we use is associated with a geographic component. In this context we are witnessing a convergence in technologies used by expert users to generic users. In this framework we look at the integration of new technologies in the control of agricultural aid. Currently, control processes agricultural subsidies are fundamentally based on field visits in order to certify the land use. This control methodology results in a significant mobilization of personnel and equipment, using devices like a camera, tablet PC, GPS, etc. The objective of this project has been to develop a mobile application taking advantage of the different sensors that are integrated into it, using terminals that add new functionality, ensuring data integrity, improving its correct interpretation as well as establishing different channels diffusion. The project has been developed under Android, using open source libraries independent to the device manufacturer. The result is software that integrates information from different sensors, introducing the mobile terminal suitable for the work of field control, reducing the material to be used and improved data integrity

Cowgotchi: un juego serio para la mejora de la motivación y el aprendizaje en alimentación animal

[ES] El Grupo Docente 44 de la Universidad de Córdoba tiene una amplia experiencia en la incorporación de herramientas innovadoras en la docencia de distintas asignaturas relacionadas con el área de la Producción Animal. En este trabajo se describe la implementación de una nueva herramienta: la gamificación aplicada a los ejercicios de racionamiento animal. El objetivo esta nueva herramienta es la mejora de la motivación y el aprendizaje de los estudiantes de la asignatura “Ingeniería y Tecnología de la Producción Animal”. Se ha desarrollado un juego serio en forma de aplicación Android inspirado en el Tamagotchi® de Bandai, juego muy popular en los años 2000 que se basaba en cuidar y alimentar una mascota virtual para mantenerla viva y obtener diversas bonificaciones. En este caso se trata de calcular raciones adecuadas que permitan mantener viva una vaca lechera, cuidar su salud y maximizar la producción de leche minimizando el coste de la alimentación. Se describe el funcionamiento del juego y los siguientes pasos para mejorar el carácter de juego serio de la aplicación móvil desarrollada.[EN] The Teaching Group no. 44 of the University of Cordoba has extensive experience in incorporating innovative tools in teaching different subjects related to the area of Animal Production. This work describes the implementation of a new tool: gamification applied to animal rationing exercises. The objective of this new tool is to improve the motivation and learning of the students of the subject "Engineering and Technology for Animal Production". A serious game has been developed, in the form of an Android app, inspired by Bandai's Tamagotchi®, a very popular game in the 2000s that was based on caring for and feeding a virtual pet to keep it alive and get different bonuses. In this case, the game is about the calculation of adequate rations to keep a dairy cow alive, take care of its health and maximize milk production while minimizing the cost of feeding. Current game functioning and the planned steps to improve the its characteristics of serious game are described.Maroto Molina, F.; Adame Siles, JA.; Riccioli, C.; Garrido Varo, A.; Pérez Marín, DC. (2021). Cowgotchi: un juego serio para la mejora de la motivación y el aprendizaje en alimentación animal. En IN-RED 2020: VI Congreso de Innovación Educativa y Docencia en Red. Editorial Universitat Politècnica de València. 740-748. https://doi.org/10.4995/INRED2020.2020.12019OCS74074

RITA: a 1U multi-sensor Earth observation payload for the AlainSat-1

The Remote sensing and Interference detector with radiomeTry and vegetation Analysis (RITA) is one of the Remote Sensing payloads selected as winners of the 2nd GRSS Student Grand Challenge in 2019, to fly on board of the 3U AlainSat-1. This CubeSat is being developed by the National Space Science and Technology Center (NSSTC), United Arab Emirates University. RITA has been designed as an academic mission, which brings together students from different backgrounds in a joint effort to apply very distinct sensors in an Earth Observation mission, fusing their results to obtain higher-accuracy measurements. The main payload used in RITA is a Total Power Radiometer such as the one on board the FSSCat mission. With these radiometric measurements, soil moisture and ice thickness will be obtained. To better characterize the extensive Radio-Frequency Interferences received by EO satellites in protected bands, several RFI Detection and Classification algorithms will be included to generate a worldwide map of RFI. As a novel addition to the 3Cat family of satellites and payloads, a hyper-spectral camera with 25 bands ranging from 600 to 975 nm will be used to obtain several indexes related to vegetation. By linking these measurements with the soil moisture obtained from the MWR, pixel downscaling can be attempted. Finally, a custom- developed LoRa transceiver will be included to provide a multi-level approach to in-situ sensors: On-demand executions of the other payloads will be able to be triggered from ground sensors if necessary, as well as simple reception of other measurements that will complement the ones obtained on the satellite. The antennas for both the MWR and the LoRa experiments have been developed in-house, and will span the entirety of one of the 3U sides of the satellite. In this work, the latest development advances will be presented, together with an updated system overview and information about the operations that will be conducted. Results obtained from the test campaign are also presented in the conference

The EMT factor ZEB1 paradoxically inhibits EMT in BRAF-mutant carcinomas

Despite being in the same pathway, mutations of KRAS and BRAF in colorectal carcinomas (CRCs) determine distinct progression courses. ZEB1 induces an epithelial-to-mesenchymal transition (EMT) and is associated with worse progression in most carcinomas. Using samples from patients with CRC, mouse models of KrasG12D and BrafV600E CRC, and a Zeb1-deficient mouse, we show that ZEB1 had opposite functions in KRAS-and BRAF-mutant CRCs. In KrasG12D CRCs, ZEB1 was correlated with a worse prognosis and a higher number of larger and undifferentiated (mesenchymal or EMT-like) tumors. Surprisingly, in BrafV600E CRC, ZEB1 was associated with better prognosis; fewer, smaller, and more differentiated (reduced EMT) primary tumors; and fewer metastases. ZEB1 was positively correlated in KRAS-mutant CRC cells and negatively in BRAF-mutant CRC cells with gene signatures for EMT, cell proliferation and survival, and ERK signaling. On a mechanistic level, ZEB1 knockdown in KRAS-mutant CRC cells increased apoptosis and reduced clonogenicity and anchorage-independent growth; the reverse occurred in BRAFV600E CRC cells. ZEB1 is associated with better prognosis and reduced EMT signature in patients harboring BRAF CRCs. These data suggest that ZEB1 can function as a tumor suppressor in BRAF-mutant CRCs, highlighting the importance of considering the KRAS/BRAF mutational background of CRCs in therapeutic strategies targeting ZEB1/EMT

Uncovering new indicators to predict stability, maturity and biodiversity of compost on an industrial scale

Currently, the metagenomic study of the composting process has gained great importance since it has allowed the identification of the existence of microorganisms that, until now, had not been isolated during the process by traditional techniques. However, it is still complex to determine which bioindicators could reveal the degree of maturity and stability of a particular compost. Thereby, the main objective of this work was to demonstrate the possible correlation between traditional parameters of maturity and stability of compost, with other indicators of biodiversity in products highly heterogeneous from composting processes on an industrial scale. The results demonstrated the enormous influence of the raw materials in characterizing the products obtained. Even so, important relationships were established between the Chao1 and Shannon indexes, and certain parameters related to the maturity, stability and toxicity of the samples, such as nitrification index, humification rate, phenolic content, germination index or oxygen consumptio