Crowdsourced morphometrics data

This zip file contains geometric morphometric landmark data collected by Mechanical Turk workers, as well as BAMM input and output files

Supplementary Information: BAMM Assessment

Supplementary Information: BAMM Assessmen

Burin_et_al_suppmat

Burin_et_al_suppma

rate-smoothed mega-phylogeny of actinopterygiians

Phylogeny based upon RAXML analysis of 13 gene concatenated data set assembled using phlawd pipeline and rate-smoothed using treePL. See methods and supplemental methods for details of tree construction

National estimates of pediatric prescription-opioid overdose by year and demographics.

National estimates of pediatric prescription-opioid overdose by year and demographics.</p

Pediatric prescription-opioid overdose rate by hospital region in the United States with 95% confidence intervals in shades of gray.

The disconnected plot value in 2015 accounts for the 2015 transition from ICD-9-CM to ICD-10-CM and the change in case identification. Redline indicates an increase from 2019–2020.</p

Pediatric prescription-opioid overdose rate by age group with 95% confidence intervals in shades of gray.

The disconnected plot value in 2015 accounts for the 2015 transition from ICD-9-CM to ICD-10-CM and the change in case identification. Redline indicates an increase from 2019–2020.</p

Pediatric prescription-opioid overdose rate by sex with 95% CI in shades of gray.

The disconnected plot value in 2015 accounts for the 2015 transition from ICD-9-CM to ICD-10-CM and the change in case identification. Redline indicates an increase from 2019–2020.</p

The legacy of ICTY and its impact upon the Statue and the practice of the ICC

Legacy of ICTY and its Impact on Statute and Case Law of ICC Establishing of International Criminal Court is a significant moment in evolution of international criminal law. It is the first permanent institution of international justice with personal jurisdiction and it was founded for one purpose only - to finally end the era of impunity for war criminals all over the world. But ICC didn't appear from nowhere. There was a long road towards its establishment and who knows if it would ever happen without influence of so called ad hoc tribunals, International Criminal Tribunal for the former Yugoslavia and International Criminal Tribunal for Rwanda. It is a sad truth that international criminal law made its biggest evolution as a reflection of the world's most horrible conflicts. The purpose of this thesis is to analyze a legacy of one of these tribunals, International Criminal Tribunal for the former Yugoslavia, and to explore its influence not only on the Statute of International Criminal Court, but also on its case law. International Criminal Court is not operating for long, but we can still notice many references on ICTY case law in its judgments. The reason for this research is my particular relation towards Balkan region as well as my interest in international justice in general. The thesis is composed..

A Chemically Induced Vaccine Strategy for Prostate Cancer

Here we report the design and evaluation of a bifunctional, small molecule switch that induces a targeted immune response against tumors <i>in vivo</i>. A high affinity ligand for prostate specific membrane antigen (PSMA) was conjugated to a hapten that binds dinitrophenyl (DNP)-specific antibodies. When introduced into hu-PBL-NOD/SCID mice previously immunized with a KLH-DNP immunogen, this conjugate induced a targeted antibody-dependent cellular cytotoxicity (ADCC) response to PSMA-expressing tumor cells in a mouse xenograft model. The ability to create a small molecule inducible antibody response against self-antigens using endogenous non-autoreactive antibodies may provide advantages over the autologous immune response generated by conventional vaccines in certain therapeutic settings