A Nonclassical Dihydrogen Adduct of S = ½ Fe(I)

We have exploited the capacity of the “(SiP^(iPr)_3)Fe(I)” scaffold to accommodate additional axial ligands and characterized the mononuclear S = 1/2 H_2 adduct complex (SiP^(iPr)_3)Fe^I(H_2). EPR and ENDOR data, in the context of X-ray structural results, revealed that this complex provides a highly unusual example of an open-shell metal complex that binds dihydrogen as a ligand. The H2 ligand at 2 K dynamically reorients within the ligand-binding pocket, tunneling among the energy minima created by strong interactions with the three Fe–P bonds

A Synthetic Theory of Political Sociology: Bringing Social Networks and Power Dependence to Power Resources Theory in City Politics

It is well established that power is connected to networks, yet structural theories of power in network analysis fail to satisfy political sociologists. Centrality is generally put forward as a measure of power, but this is not enough for political sociology. This article puts forward a theory of power that brings power resources and power dependency theory to the study of social networks concerning political coalitions in an urban polity. Within this theory of power resources, we embed power theories based on dependence (exchange theories) with power being based on the inverse of the expected value of alternative courses of action, and social network analysis focused on networks of powerful actors with significant power resources. The use of social networks depends on the formation of coalitions of powerful individuals and groups who then engage in political bargaining with other coalitions who want a different outcome. This synthetic theory is illustrated with two examples of economic development and political conflict in a moderately sized city

Lysosomal sulfate transport: inhibitor studies

AbstractSulfate derived from the degradation of macromolecules is released from lysosomes via a carrier mediated process. In order to further characterize this process, recognized inhibitors of the erythrocyte band 3 anion transporter were examined for their effects on the lysosomal system. Studies with band 3 transport site inhibitors such as DIDS, SITS and phenylglyoxal indicated that, similar to the case for the band 3 protein, the llysosomal transporter has critical lysine and arginine residues. Band 3 translocation pathway or channel blocking inhibitors had mixed effects on the lysosomal system. 1,2-Cyclohexanedione, which covalently modifies a band 3 arginine residue distinct from that modified by phenylglyoxal, inhibited lysosomal sulfate transport. In contrast, the potent band 3 inhibitor dipyridamole had no effect on lysosomal sulfate transport indicating that there are some structural differences between the erythrocyte and lysosomal anion transporters. The band 3 translocation inhibitors niflumic acid and dinitrofluorobenzene were both effective inhibitors of the lysosomal system. Cupric ion inhibited sulfate transport while Ca2+, Co2+, Mg2+, Mn2+, and Zn2+ had no inhibitory effects. Exposure of intact lysosomes to trypsin largely ablated transport of sulfate. This information should be useful in efforts to further elucidate the structure and function of the lysosomal sulfate transporter