136,868 research outputs found
Computing only minimal answers in disjunctive deductive databases
A method is presented for computing minimal answers in disjunctive deductive
databases under the disjunctive stable model semantics. Such answers are
constructed by repeatedly extending partial answers. Our method is complete (in
that every minimal answer can be computed) and does not admit redundancy (in
the sense that every partial answer generated can be extended to a minimal
answer), whence no non-minimal answer is generated. For stratified databases,
the method does not (necessarily) require the computation of models of the
database in their entirety. Compilation is proposed as a tool by which problems
relating to computational efficiency and the non-existence of disjunctive
stable models can be overcome. The extension of our method to other semantics
is also considered.Comment: 48 page
Coulomb-Modified Fano Resonance in a One-Lead Quantum Dot
We investigate a tunable Fano interferometer consisting of a quantum dot
coupled via tunneling to a one-dimensional channel. In addition to Fano
resonance, the channel shows strong Coulomb response to the dot, with a single
electron modulating channel conductance by factors of up to 100. Where these
effects coexist, lineshapes with up to four extrema are found. A model of
Coulomb-modified Fano resonance is developed and gives excellent agreement with
experiment.Comment: related papers available at http://marcuslab.harvard.ed
BRCA1 Zinc RING Finger Domain Disruption Alters Caspase Response in Ovarian Surface Epithelial Cells
BACKGROUND: The frequently occurring 185delAG mutation occurs in the amino-terminal zinc RING domain of the breast and ovarian cancer susceptibility gene, BRCA1. We sought to determine differential cell viability and apoptotic response of human ovarian surface epithelial cells with and without the 185delAG mutation. RESULTS: BRCA1wt and BRCA1+ cells were treated with staurosporine. Cell proliferation assays showed BRCA1wt cells grew to a greater extent compared to BRCA1+ cells. Trypan blue exclusion assays confirmed this observation. Western immunoblot analysis revealed that caspase 3 levels were higher after staurosporine treatment in BRCA1+ cells than in wild type cells, while full length DNA Fragmentation Factor 45 levels were lower in BRCA1+ cells. While there was no significant difference in levels of excision repair cross complementing protein1 (ERCC1) with BRCA1 status, BRCA1+ cells demonstrated cleavage of polyribose ADP polymerase (PARP) before wild type cells. CONCLUSIONS: Disruption of the BRCA1 RING domain caused altered cell viability and caspase-dependent apoptotic response after chemotoxic stress
A new puzzle for random interaction
We continue a series of numerical experiments on many-body systems with
random two-body interactions, by examining correlations in ratios in excitation
energies of yrast = 0, 2, 4, 6, 8 states. Previous studies, limited only to
= 0,2,4 states, had shown strong correlations in boson systems but not
fermion systems. By including states and considering different
scatter plots, strong and realistic correlations appear in both boson and
fermion systems. Such correlations are a challenge to explanations of random
interactions.Comment: 4 pages, 4 figure
Psychological Contracts, OCB and Customer Service: An Exploratory Examination
This paper examines the relationships among the psychological contract, fairness, OCB, and customer service. We report on two exploratory studies that provide insight into psychological contract violations and subsequent perceptions of fairness, as well as OCB activity. A linkage is made between psychological contracts and behavior directed internally and those directed externally (i.e., customer service). We extend the current theory to suggest implications for effectively managing customer service employee OCB. Finally, suggestions are made for both practice and future research to be conducted in a multidisciplinary design
A comparative study of two 47 Tuc giant stars with different s-process enrichment
Here we aim to understand the origin of 47 Tuc's La-rich star Lee 4710. We
report abundances for O, Na, Mg, Al, Si, Ca, Sc, Ti, V, Cr, Co, Ni, Zn, Y, Zr,
Ba, La, Ce, Pr, Nd, and Eu, and present a detailed abundance analysis of two 47
Tuc stars with similar stellar parameters but different slow neutron-capture
(s-)process enrichment. Star Lee 4710 has the highest known La abundance ratio
in this cluster ([La/Fe] = 1.14), and star Lee 4626 is known to have normal
s-process abundances (e.g., [Ba/Eu]). The nucleosynthetic pattern of
elements with Z56 for star Lee 4710 agrees with the predicted yields
of a asymptotic giant branch (AGB) star. Therefore, Lee 4710 may
have been enriched by mass transfer from a more massive AGB companion, which is
compatible with its location far away from the center of this relatively
metal-rich ([Fe/H]) globular cluster. A further analysis comparing
the abundance pattern of Lee 4710 with data available in the literature reveals
that nine out of the 47 Tuc stars previously studied show strong
s-process enhancements that point towards later enrichment by more massive AGB
stars.Comment: ApJL in press. 6 pages, 4 figure
Medical operations and life sciences activities on space station
Space station health maintenance facilities, habitability, personnel, and research in the medical sciences and in biology are discussed. It is assumed that the space station structure will consist of several modules, each being consistent with Orbiter payload bay limits in size, weight, and center of gravity
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