Extreme Measures of Agricultural Financial Risk

This paper is from the Centre for Financial Markets (CFM) Working Paper series at University College Dublin.Agricultural financial risk, Spectral risk measures, Expected Shortfall, Value at Risk, Extreme Value Theory., Agricultural Finance, Risk and Uncertainty, E17, G19, N52,

The Tragic Sense of Life: The Philosophy of Miguel de Unamuno

The major thesis of this research work has been that Unamuno’s life and writings can best be seen in terms of a philosophy of tragedy. Tragedy, in the Unamunian sense, means an agonizing struggle between opposing forces so well matched that no final victory of one over the other is possible. Unamuno wrote about and lived within this “tragic sense of life,” which consists of this agonizing struggle; and it is the centrality of this fact which can be demonstrated in his writings. Unamuno’s own life and the life of the so-called “Generation of 1898” serves as an introduction to the meaning of the tragic sense of life in human existence and in the Christian faith. Moreover, it has also been the concern of this thesis to show that the tragic sense of 1ife, far from being the occasion for resignation, is a source of creativity for Christian existence. In short, I have attempted to demonstrate how conflicting modes of being – heart and head, faith and reason, peace and conflict, life and logic – struggled with each other in the Unamunian universe, and how they could lead to creative courage and meaning

The Welfare Effects of Pfiesteria-Related Fish Kills: A Contingent Behavior Analysis of Seafood Consumers

We use contingent behavior analysis to study the effects of pfiesteria-related fish kills on the demand for seafood in the Mid-Atlantic region. We estimate a set of demand difference models based on individual responses to questions about seafood consumption in the presence of fish kills and with different amounts of information provided about health risks. We use a random-effects Tobit model to control for correlation across each observation and to account for censoring. We find that (i) pfiesteria-related fish kills have a significant negative effect on the demand for seafood even though the fish kills pose no known threat to consumers through sea-food consumption, (ii) seafood consumers are not responsive to expert risk information designed to reassure them that seafood is safe in the presence of a fish kill, and (iii) a mandatory seafood inspection program largely eliminates the welfare loss incurred due to misinformation.pfiesteria, seafood demand, non-market valuation, Resource /Energy Economics and Policy,

The Welfare Effects of Pfiesteria-Related Fish Kills in Seafood Markets: A Contingent Behavior Analysis

We use contingent behavior analysis to study the effects of Pfiesteria related fish kills on the demand for seafood in the Mid-Atlantic region. We use a phone-mail-phone survey to look at the effects of various information provision mechanisms used to ameliorate the effects of misinformation regarding fish kills. A set of demand difference models are estimated based on individual responses to multiple questions about seafood consumption with and without fish kills present and with various health risk information treatments. Random effects Tobit models are used to control for the panel nature of responses and natural censoring of the stated responses. We find that 1) Pfiesteria related fish kills have a significant negative effect on the demand for seafood, 2) seafood consumers are nonresponsive to expert risk information designed to reassure consumers that seafood is safe in the presence of a fish kill, and 3) a mandatory seafood inspection program completely eliminates avoidance costs incurred due to misinformation. We estimate that the aggregate avoidance costs incurred in the month immediately following a Pfiesteria related fish kill is $50-$130 million.

Economic Impacts of Ethanol Production in Georgia

Capital costs to construct a conventional ethanol plant producing 100 million gallons per year are $170.593 million. Average annual net returns average$59.216 million with a 1% chance of annual net returns less than $0. Ethanol production stimulates total economic output of$314.221 million in the Georgia economy. Wages and benefits total $20.181 million for 408 jobs in Georgia. State and local governments derive a total of$4.572 million in tax revenues from ethanol production.Resource /Energy Economics and Policy,

The alchemical energy landscape for a pentameric cluster.

We investigate the energy landscape of an alchemical system of point particles in which the parameters of the interparticle potential are treated as degrees of freedom. Using geometrical optimization, we locate minima and transition states on the landscape for pentamers. We show that it is easy to find the parameters that give the lowest energy minimum and that the distribution of minima on the alchemical landscape is concentrated in particular areas. In contrast to the usual changes to an energy landscape when adding more degrees of freedom, we find that introducing alchemical degrees of freedom can reduce the number of minima. Moreover, compared to landscapes of the same system with fixed parameters, these minima on the alchemical landscape are separated by high barriers. We classify transition states on the alchemical landscape by whether they become minima or remain transition states when the potential parameters are fixed at the stationary point value. We show that those that become minima have a significant alchemical component in the direction of the pathway, while those that remain as transition states can be characterized mainly in terms of atomic displacements.Simons Foundation (256297

CpG island composition differences are a source of gene expression noise indicative of promoter responsiveness.

BACKGROUND: Population phenotypic variation can arise from genetic differences between individuals, or from cellular heterogeneity in an isogenic group of cells or organisms. The emergence of gene expression differences between genetically identical cells is referred to as gene expression noise, the sources of which are not well understood. RESULTS: In this work, by studying gene expression noise between multiple cell lineages and mammalian species, we find consistent evidence of a role for CpG islands as sources of gene expression noise. Variation in noise among CpG island promoters can be partially attributed to differences in island size, in which short islands have noisier gene expression. Building on these findings, we investigate the potential for short CpG islands to act as fast response elements to environmental stimuli. Specifically, we find that these islands are enriched amongst primary response genes in SWI/SNF-independent stimuli, suggesting that expression noise is an indicator of promoter responsiveness. CONCLUSIONS: Thus, through the integration of single-cell RNA expression profiling, chromatin landscape and temporal gene expression dynamics, we have uncovered a role for short CpG island promoters as fast response elements

Bilateral Facial Spasm Following Guillain–Barré Syndrome

Background: We report a patient who developed lower facial muscle spasm at rest and bilateral facial synkinesis several months after treatment of Guillain–Barré syndrome (GBS); this finding, to our knowledge, is hitherto unreported. Phenomenology Shown: Bilateral synkinesis, facial muscles spasm at rest, bilateral postparalytic facial syndrome. Educational Value: Aberrant regeneration of nerve fibers post GBS, resulting in facial muscles spasm at rest, bilateral synkinesis