26 research outputs found
Leave No Charter Behind: An Authorizer Guide to the Use of Growth Data
The purpose of this brief is to guide the reader in the effective use of data for measuring student academic growth. It explores the use of different measurement models in school accountability systems. While targeted to the authorizers of charter schools, the brief is helpful to anyone who evaluates the performance of a portfolio of schools
Risk factors for Coronavirus disease 2019 (Covid-19) death in a population cohort study from the Western Cape province, South Africa
Risk factors for coronavirus disease 2019 (COVID-19) death in sub-Saharan Africa and the effects of human immunodeficiency virus (HIV) and tuberculosis on COVID-19 outcomes are unknown. We conducted a population cohort study using linked data from adults attending public-sector health facilities in the
Western Cape, South Africa. We used Cox proportional hazards models, adjusted for age, sex, location, and comorbidities, to examine the associations between HIV, tuberculosis, and COVID-19 death from 1 March to 9 June 2020 among (1) public-sector “active patients” (≥1 visit in the 3 years before March 2020); (2) laboratory-diagnosed COVID-19 cases; and (3) hospitalized COVID-19
cases. We calculated the standardized mortality ratio (SMR) for COVID-19, comparing adults living with and without HIV using
modeled population estimates.Among 3 460 932 patients (16% living with HIV), 22 308 were diagnosed with COVID-19, of whom 625 died. COVID19 death was associated with male sex, increasing age, diabetes, hypertension, and chronic kidney disease. HIV was associated with
COVID-19 mortality (adjusted hazard ratio [aHR], 2.14; 95% confidence interval [CI], 1.70–2.70), with similar risks across strata of
viral loads and immunosuppression. Current and previous diagnoses of tuberculosis were associated with COVID-19 death (aHR,
2.70 [95% CI, 1.81–4.04] and 1.51 [95% CI, 1.18–1.93], respectively). The SMR for COVID-19 death associated with HIV was 2.39
(95% CI, 1.96–2.86); population attributable fraction 8.5% (95% CI, 6.1–11.1)
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Genetic and environmental influences of maternal psychosocial and antisocial tendencies on the development, stability, and continuity of problem behaviors in adoptees from the Texas Adoption Project: a life course investigation of risk, resilience, and vulnerability
Utilizing a 30 year longitudinal investigation of 300 adoptive families, the influence of
both general and specific maternal psychological functioning on the development,
stability, and continuity of problem behaviors was investigated. In the first part of the
investigation, biological and adoptive mothers’ scores on eight subscales from the
Minnesota Multiphasic Personality Inventory were investigated to discover whether
general psychosocial functioning, defined as the number of elevated subscales scores, or
specific subscales were related to problem behavior development during childhood,
adolescence, and adulthood. Based on earlier findings from the Texas Adoption Project
(Loehlin, Willerman, & Horn, 1982, 1987), it was predicted that birth mothers’ general
psychosocial functioning would predict problem behavior development in their adopted
away offspring during adolescence and adulthood, but that the adoptive mothers’ general
functioning would predict behavior problems during childhood. I also predicted that the
birth mothers’ specific subscales, namely the psychopathic deviate scale, would be the
strongest predictor of adoptee behavior problems across the entire life span. These
hypotheses were generally supported. In the second part of the investigation, the stability
and continuity of problem behaviors were assessed to explore whether mean and intraindividual
trends in behavior, from childhood through middle-adulthood, differ as a
function of gender, adoptive status, and relative risk status. Genetic and shared
environmental influences on problem behavior development and continuity were also
investigated using correlations between biologically related and non-related sibling pairs.
Trends in both mean behavioral stability and intra-individual continuity were found to
differ between groups and genetic effects were found for the development of, but not
continuity in, problem behaviors. Finally, individual and family environmental
characteristics were investigated as potential risk or protective factors for two groups of
adoptees that varied in the amount of genetic risk they faced for problem behavior
development. Findings from the investigation highlight the necessity for using genetically
informative, longitudinal samples to investigate the influence of maternal psychological
functioning on the development of problem behavior. The importance of conducting
analyses of the influences of genetics and environmental factors separately for males and
females, as well as for Higher-Risk individuals, is also addressed.Psycholog